Hi Wayne,
I hope you are well, sorry about the moaning on my last post but was really felling like S... i stopped taking all the meds and i am just taking the Aloe Vera tabs now, and just a couple of pain killers for the carpol tunnel.
Wayne seeing as you are the most inteligent person i know where meds are concerned i was wondering if you could let me know if you know anything about a steriod called PRENISALONE. I have been looking it up on the net and i dont like what im reading i might be wrong. The reason i want to know is that my niece is on her fourth try at IVF and the doctor is so called baffeled as to why she has'nt fell pregnant, as she already has an eight year old son and is desperate for another child. She has already tried 3 times, now the doctor is going to put her on this steriod which he is saying cannot fail, but from what i have read it is mainly people who suffer with astma that take this steroid.
I would really appreciate your opinion on this.
Thanks
God bless,
Love Bobbie.
question for Wayne
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Hi Bobbie,
Please remember that I'm not a medical professional, so anything that I tell you is strictly unofficial, and would need to be reviewed with a doctor, before you consider acting on any of this information.
Having said that, frankly, I don't see why any doctor would be willing to put one of his or her patients at such considerable risk, in order to help induce pregnancy, unless all alternative possibilities have been exhausted, and the patient thouroughly understands, and accepts, all the risks involved. I assume that you're referring to prednisolone, and using a powerful drug such as that, is a rather risky way to accomplish the goals. True, it might be effective, but there are much safer ways to accomplish the desired results.
Prednisolone is the active drug found in prednisone, and it is just as risky, as far as patient health is concerned. It is the same stuff used to treat Crohn's disease, arthritis, and various other autoimmune issues, such as asthma, which you mentioned.
Prednisone is rapidly converted in the liver to prednisolone. Except in cases of severe liver disease, the drugs are considered to be equivalent.
Here is a quote describing some of the risks involved, for this type of use:
"Women of childbearing age invariably mix with other women with young children, thus exposing themselves to chicken pox and measles – these can be fatal if contracted while taking Prednisalone! As if that were not enough the drug can enhance the effects of hypothyroidism and cirrhosis. It can induce mood swings, personality changes, severe depression and frank psychotic manifestations. Anyone with ulcerative colitis should take care as ulcer perforation risk is increased. Recorded side effects include sodium retention, fluid retention, congestive heart failure, potassium loss, hypertension, pancreatitis, latent diabetes and decreased carbohydrate tolerance and convulsions. Menstrual irregularities, headaches, increased sweating and abdominal distention only add to the misery."
The quote comes from this website:
http://www.epc-odx.com/articles/Prednisalone.htm
The site suggests some alternative, safer ways to accomplish the desired goal.
Apparently the use of prednisolone for this purpose is based on very recent research. (the website article sites a Brittish news release dated June 21, 2005). I'm guessing that it will probably be a somewhat popular treatment for a while, until reports of all the serious side effects of prednisolone start pouring in, and it becomes obvious that the the risks are too great to justify the use of prednisolone for this purpose.
Here's why prednisolone sometimes helps to allow a pregnancy to be successful. The treatment helps in cases where an overactive immune system is causing the death of the fetus. The immune system is designed to hunt down and kill foreign invaders, or anything that it perceives as ‘non-self’. A fetus is partially ‘non-self’ (as it is derived, at least in part, from the father). Therefore, in order to allow the fetus to grow and develop, the immune system switches from a state known as Th1, to Th2, (Th2 is a state reserved for wound healing and pregnancy). Constant immune activation reverses this switching ability, which leaves the fetus at the mercy of the Th1 type immunity. IOW, if the mother has an overactive immune system, the fetus is vulnerable to being destroyed by an autoimmune reaction, unless the overactive immune system is suppressed.
I guess the bottom line depends on how much risk your neice is willing to accept for her own health and safety, in order to become pregnant.
I hope you're feeling much better than you were the last time you were here.
Love,
Wayne
Please remember that I'm not a medical professional, so anything that I tell you is strictly unofficial, and would need to be reviewed with a doctor, before you consider acting on any of this information.
Having said that, frankly, I don't see why any doctor would be willing to put one of his or her patients at such considerable risk, in order to help induce pregnancy, unless all alternative possibilities have been exhausted, and the patient thouroughly understands, and accepts, all the risks involved. I assume that you're referring to prednisolone, and using a powerful drug such as that, is a rather risky way to accomplish the goals. True, it might be effective, but there are much safer ways to accomplish the desired results.
Prednisolone is the active drug found in prednisone, and it is just as risky, as far as patient health is concerned. It is the same stuff used to treat Crohn's disease, arthritis, and various other autoimmune issues, such as asthma, which you mentioned.
Prednisone is rapidly converted in the liver to prednisolone. Except in cases of severe liver disease, the drugs are considered to be equivalent.
Here is a quote describing some of the risks involved, for this type of use:
"Women of childbearing age invariably mix with other women with young children, thus exposing themselves to chicken pox and measles – these can be fatal if contracted while taking Prednisalone! As if that were not enough the drug can enhance the effects of hypothyroidism and cirrhosis. It can induce mood swings, personality changes, severe depression and frank psychotic manifestations. Anyone with ulcerative colitis should take care as ulcer perforation risk is increased. Recorded side effects include sodium retention, fluid retention, congestive heart failure, potassium loss, hypertension, pancreatitis, latent diabetes and decreased carbohydrate tolerance and convulsions. Menstrual irregularities, headaches, increased sweating and abdominal distention only add to the misery."
The quote comes from this website:
http://www.epc-odx.com/articles/Prednisalone.htm
The site suggests some alternative, safer ways to accomplish the desired goal.
Apparently the use of prednisolone for this purpose is based on very recent research. (the website article sites a Brittish news release dated June 21, 2005). I'm guessing that it will probably be a somewhat popular treatment for a while, until reports of all the serious side effects of prednisolone start pouring in, and it becomes obvious that the the risks are too great to justify the use of prednisolone for this purpose.
Here's why prednisolone sometimes helps to allow a pregnancy to be successful. The treatment helps in cases where an overactive immune system is causing the death of the fetus. The immune system is designed to hunt down and kill foreign invaders, or anything that it perceives as ‘non-self’. A fetus is partially ‘non-self’ (as it is derived, at least in part, from the father). Therefore, in order to allow the fetus to grow and develop, the immune system switches from a state known as Th1, to Th2, (Th2 is a state reserved for wound healing and pregnancy). Constant immune activation reverses this switching ability, which leaves the fetus at the mercy of the Th1 type immunity. IOW, if the mother has an overactive immune system, the fetus is vulnerable to being destroyed by an autoimmune reaction, unless the overactive immune system is suppressed.
I guess the bottom line depends on how much risk your neice is willing to accept for her own health and safety, in order to become pregnant.
I hope you're feeling much better than you were the last time you were here.
Love,
Wayne
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Thanks Wayne
I know your not a doctor but to me you are very intelegent and you have confirmed what i have been reading, my niece was told that the steriod would lower her imune system as her body was rejecting the eggs but i dont think she has been told any of the side effects which to me sound horrific. so thanks for that wayne i will tell my sister and put the ball in her court and then it is up to her if she decides to tell her daughter.
God bless,
And thanks again
Bobbie
God bless,
And thanks again
Bobbie