Researching bone density in mc recently and came across this research done last year ... Members may find this informative...
http://www.biomedcentral.com/content/pd ... -11-58.pdf
Angy
Low bone mass in microscopic colitis
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Hi Angy,
That's a good article. It would have been a lot more meaningful if they had separated users of corticosteroids, and non-users, but instead, they excluded anyone from the MC group who had taken Budesonide within the previous 6 weeks, but excluded any Crohn's patients who had used a corticosteroid with in the past year. MC subjects had to be in remissionll at the start, and Crohn's subjects had to have been in remission for a year. That's a strange way to go about it. It appears that they mistakenly assume that budesonide taken prior to the six week limit has absolutely no effect on bone density, (which is obviously wrong), and they mistakenly assume that any corticosteroid discontinued more than a year before the trial does not affect bone density, (as if bone density loss will be rebuilt during that year without corticosteroids
). Again, that's obviously incorrect, so the data have to be slanted, but still it confirms what most of us have suspected, (namely that MC and Crohn's both are associated with gluten-sensitivity, which leads to loss of bone density. Of course, they conveniently never mentioned diet in the report, (if they did, I completely overlooked it).
It's a good start, though, and it provides more circumstantial evidence that gluten-sensitivity and it's effects on bone-loss are indeed associated with MC, (even though they failed to even consider that point).
Thanks, Angy,
Tex
That's a good article. It would have been a lot more meaningful if they had separated users of corticosteroids, and non-users, but instead, they excluded anyone from the MC group who had taken Budesonide within the previous 6 weeks, but excluded any Crohn's patients who had used a corticosteroid with in the past year. MC subjects had to be in remissionll at the start, and Crohn's subjects had to have been in remission for a year. That's a strange way to go about it. It appears that they mistakenly assume that budesonide taken prior to the six week limit has absolutely no effect on bone density, (which is obviously wrong), and they mistakenly assume that any corticosteroid discontinued more than a year before the trial does not affect bone density, (as if bone density loss will be rebuilt during that year without corticosteroids
). Again, that's obviously incorrect, so the data have to be slanted, but still it confirms what most of us have suspected, (namely that MC and Crohn's both are associated with gluten-sensitivity, which leads to loss of bone density. Of course, they conveniently never mentioned diet in the report, (if they did, I completely overlooked it).It's a good start, though, and it provides more circumstantial evidence that gluten-sensitivity and it's effects on bone-loss are indeed associated with MC, (even though they failed to even consider that point).
Thanks, Angy,
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
