I Had An Epiphany, Tonight :shock:
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
I Had An Epiphany, Tonight :shock:
Hi All,
This is premature, and I can't post any details yet, (for one thing, I haven't worked out all the details, so it may not even pan out in the end), but I think that I may have figured out the primary cause of MC. And, of course, I have no way to prove it, so the best that I will be able to do is to develop a theory, but at the moment, it looks very promising, (of course, maybe I'm a bit biased. LOL ).
If it makes sense, after I consider all the "boundary conditions", I'm considering devoting the next to last chapter in the book to it.
Sorry to keep you hanging, but I can't afford to spill the beans prematurely, so it will probably have to appear in the book, first, before I can safely post it here, for all the world to see.
Love,
Tex
This is premature, and I can't post any details yet, (for one thing, I haven't worked out all the details, so it may not even pan out in the end), but I think that I may have figured out the primary cause of MC. And, of course, I have no way to prove it, so the best that I will be able to do is to develop a theory, but at the moment, it looks very promising, (of course, maybe I'm a bit biased. LOL ).
If it makes sense, after I consider all the "boundary conditions", I'm considering devoting the next to last chapter in the book to it.
Sorry to keep you hanging, but I can't afford to spill the beans prematurely, so it will probably have to appear in the book, first, before I can safely post it here, for all the world to see.
Love,
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
- MaggieRedwings
- King Penguin
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Well, that's certainly tantalizing to all of us. Is this a ploy to get us to buy the book? We were all interested in it before the carrot was dangled, of course.
I hope you will bounce your theory off of someone who can give an educated opinion, perhaps Polly.
Gloria
I hope you will bounce your theory off of someone who can give an educated opinion, perhaps Polly.
Gloria
You never know what you can do until you have to do it.
No, in fact, IMO, if this is the cause, then it just complicates the issue, and illuminates why the disease can be so difficult to control.Lesley wrote:If you know the cause do you know the cure too?
No. I'll definitely post all the info, once it's published. I realize that it could be published online, but the problem with distributing information online is that attributions tend to be quickly lost or diluted on the internet. When information first appears in a book, though, it's pretty tough to dispute who said what, first.Gloria wrote:Is this a ploy to get us to buy the book?
I would love to do that, but that's easier said than done. Unfortunately, Polly has her plate pretty full these days, and she really doesn't need any additional distractions. With her being currently unavailable, there really are no remaining options. I'm not aware of any GPs who know enough about the disease to even talk intelligently about it, let alone any who might be qualified to make a judgment about the validity of a theory of the etiology of the disease.Gloria wrote:I hope you will bounce your theory off of someone who can give an educated opinion, perhaps Polly.
I don't have access to Dr. Lewey, since I'm not a Colorado resident, and Dr. Fine seems to be burned out on MC research, and I'm sure that he wouldn't be willing to do it. So that leaves me high and dry. Can you imagine how virtually any other GI specialist would respond? My guess is that most of them would laugh me out of their office, and probably a few of them would steal the idea for their own. Maybe I'm looking at this wrong, but that seems like a blind alley, to me.
I'm not trying to imply that the theory is worth money, because it probably isn't. Treatments are worth money, but causes of a disease are not. Of course, knowing the cause, can certainly facilitate selecting a treatment, or even possibly preempting the development of the disease. At any rate, I'm just saying that it's intellectual property, and preserving the rights to intellectual property of this type is easier said than done.
The other point is that whenever a new concept is introduced in a medical or scientific environment, everyone and his dog in that profession will go out of their way to prove the theory wrong. Unfortunately, that's the name of the game, but it's the primary reason why creative thinkers get no respect from their peers. Anyone who rocks the boat, immediately has no friends, at least not in expert circles.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Hi Zizzle,
I'm trying to finish the chapter that I was writing when the inspiration hit me, so I still haven't had time to think through all the connections, but my initial impression is that the development of the disease may depend on a unique chain of events that is initiated by a common environmental phenomenon, and once the dominoes start to fall, the process may be self-perpetuating. Since I haven't thought through all the details, I'm not exactly sure if gluten has a primary or a secondary role in the scheme of things, but I'm pretty sure that it plays an important role - almost certainly much more important in some cases, than in others, but it may possibly be a vital ingredient in all cases.
I'll give you a big hint - if I'm right, it's the "missing link" in the development of not only MC, but very likely also celiac disease and the other IBDs, as well. Now I'm wondering whether to change the title, target audience, and layout of the book. It already contains a lot of celiac-related information that most celiacs probably aren't aware of.
Even though I provide documentation for virtually everything that needs documentation, the book is going to contain so many new concepts/observations/theories, etc., that almost everyone who reads the book will probably brand me as a kook. That's not a problem for me, though - I've always been different.
Though it isn't obvious on the surface, the link that you posted about the breast cancer connection with colonic histology changes that mimic MC, provided additional insight that supports my theory, and convinces me that I'm on the right track. Thanks.
Tex
I'm trying to finish the chapter that I was writing when the inspiration hit me, so I still haven't had time to think through all the connections, but my initial impression is that the development of the disease may depend on a unique chain of events that is initiated by a common environmental phenomenon, and once the dominoes start to fall, the process may be self-perpetuating. Since I haven't thought through all the details, I'm not exactly sure if gluten has a primary or a secondary role in the scheme of things, but I'm pretty sure that it plays an important role - almost certainly much more important in some cases, than in others, but it may possibly be a vital ingredient in all cases.
I'll give you a big hint - if I'm right, it's the "missing link" in the development of not only MC, but very likely also celiac disease and the other IBDs, as well. Now I'm wondering whether to change the title, target audience, and layout of the book. It already contains a lot of celiac-related information that most celiacs probably aren't aware of.
Even though I provide documentation for virtually everything that needs documentation, the book is going to contain so many new concepts/observations/theories, etc., that almost everyone who reads the book will probably brand me as a kook. That's not a problem for me, though - I've always been different.
Though it isn't obvious on the surface, the link that you posted about the breast cancer connection with colonic histology changes that mimic MC, provided additional insight that supports my theory, and convinces me that I'm on the right track. Thanks.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
It seems EVERYONE I know is coming down with either autoimmune disease, cancer, crazy allergies, and food intolerances, seemingly all in the last 10 years. I have 3 new GF friends as of this week!! I need to start charging for my advice!
My theory is headed this way--- we humans are simply parasitic hosts, which have become inhabited by one or several mutated/adapted bacteria and/or viruses that take up residence in our cells to survive. Overuse of antibiotics, pesticides, food manufuacturing practices, etc have forced our microbes to evolve so they can fly under the radar of antibiotics and other treatments. It's survival of the fittest, and we will all eventually succumb to one or many of our resident microbes. I'm beginning to think all inflammation and all cancer ultimately have a microbial cause at their root. It took decades to figure that out with HPylori and ulcers, or HPV and cervical cancer.
I'm also beginning to think that people with gluten intolerance share a common microbe - one that subsists on gluten. Maybe it's MAP, I don't know. If we feed it, it proliferates, and our body does what it can to attack it.
Am I all wet?
My theory is headed this way--- we humans are simply parasitic hosts, which have become inhabited by one or several mutated/adapted bacteria and/or viruses that take up residence in our cells to survive. Overuse of antibiotics, pesticides, food manufuacturing practices, etc have forced our microbes to evolve so they can fly under the radar of antibiotics and other treatments. It's survival of the fittest, and we will all eventually succumb to one or many of our resident microbes. I'm beginning to think all inflammation and all cancer ultimately have a microbial cause at their root. It took decades to figure that out with HPylori and ulcers, or HPV and cervical cancer.
I'm also beginning to think that people with gluten intolerance share a common microbe - one that subsists on gluten. Maybe it's MAP, I don't know. If we feed it, it proliferates, and our body does what it can to attack it.
Am I all wet?
There's plenty of evidence to suggest that you're right. If cats and dogs can train humans to take care of them, hand and foot, (and persuade humans to actually feel that they're the ones in charge, and that they are the ones benefiting from the arrangement) - just imagine what microbes can do. Microbes are well organized to work very efficiently in unison, even though they might be comprised of billions of individual members. Dogs and cats, on the other hand, typically operate as individuals, and rarely try to organize beyond a handful of individuals.Zizzle wrote:Am I all wet?
Speaking of antibiotics, did you see on the news where a research project showed that antibiotics have no useful effect on sinus infections? No wonder the treatments don't seem to be very effective. LOL. Lack of effectiveness hasn't prevented doctors from prescribing antibiotics for that use so far, though, so it will be interesting to see if this news will make any difference in their habits.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Yup, I read that. Although it seems they tested amoxicillin, and I'm guessing today's true bacterial sinus infections would need something more potent. (since, according to my theory, the microbes have figured out how to evade amoxicillin by now). I'm glad to hear the news though. My daughter suffered 2 weeks of insane snotty nose. Even her teachers were asking if she needed medicine. I eventually gave her Allegra to help the drips, and she naturally got over it...until the next cold, 2 weeks later.
I'm a big fan of sinus irrigation for sinus infections. Of course a couple of people died recently by irrigating with tap water with brain-eating ameobas in it!
Remember to boil first...
I'm a big fan of sinus irrigation for sinus infections. Of course a couple of people died recently by irrigating with tap water with brain-eating ameobas in it!
Remember to boil first...
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- Rockhopper Penguin
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Tex,
So glad to hear your writing a book and hope your enjoying the process. It must be quite interesting and enlightening as you research and sift through the dense jungle of tentacles and boundary conditions as you call them, associated with MC.
Happy writing and thank you!
Love,
Joanna
So glad to hear your writing a book and hope your enjoying the process. It must be quite interesting and enlightening as you research and sift through the dense jungle of tentacles and boundary conditions as you call them, associated with MC.
Can you re post this link of Zizzles?tex wrote: Though it isn't obvious on the surface, the link that you posted about the breast cancer connection with colonic histology changes that mimic MC, provided additional insight that supports my theory, and convinces me that I'm on the right track. Thanks.
Tex
Happy writing and thank you!
Love,
Joanna
THE GLUTEN FILES
http://jccglutenfree.googlepages.com/
http://jccglutenfree.googlepages.com/
Joanna,
Post subject: This is scary....
Metastatic Breast Carcinoma to the Colon Mimicking Microscopic Colitis.” Baishali Bhattacharya, MD, Ahmed Bedeir, MD
http://www.carislifesciences.com/media/ ... Poster.pdf
Post subject: This is scary....
Metastatic Breast Carcinoma to the Colon Mimicking Microscopic Colitis.” Baishali Bhattacharya, MD, Ahmed Bedeir, MD
http://www.carislifesciences.com/media/ ... Poster.pdf