What role do fungi and mycotoxins play in MC?

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Zizzle
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What role do fungi and mycotoxins play in MC?

Post by Zizzle »

I was reviewing this top 10 list of foods containing mycotoxins, and it reads like a MC intolerance list. Is it possible some cases of MC are CAUSED by or aggravated by fungal exposure?

http://articles.mercola.com/sites/artic ... foods.aspx
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tex
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Post by tex »

Zizzle,

As I posted a while back, (if I didn't, I apologize, because I intended to - sometimes I may get posting mixed up with something that I've written in the book), IMO, molds and fungi are the source of all of the histamines in food, and they are also the source of all of the mycotoxins in food, and as I explain in my book, they are almost surely connected with the development of MC, for most of us.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by Joefnh »

Tex do you feel that specific enterotypes make one more susceptible to mycotoxins?
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tex
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Post by tex »

Joe,

I don't know much about this, (I'm not sure that anyone knows a heck of a lot about it at this point), but apparently any microbiome deficient in Bacteroides is more likely to increase the risk of developing autoimmune diseases, (assuming that Dr. Fasano knows what he's talking about). Obviously, that doesn't necessarily apply directly to mycotoxins, but I would think that mycotoxins would be less likely to cause problems in microbial environments that are generally known to be more resistant to other health issues.

Incidentally, Zizzle posted about this topic yesterday:

http://www.perskyfarms.com/phpBB2/viewtopic.php?t=15807

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by Zizzle »

I just asked my doctor about mycotoxins and their relationship to GI and autoimmune diseases. He said not much is known about this yet, so he couldn't give an opinion. He said people would respond differently to them based on their specific genes and flora, so it's probably not a singular cause in any disease. However, he does treat patients with mycotoxicity -- these are people who truly are intolerant to mycotoxins. Perhaps there is a continuum in mycotoxin tolerance, as in many other things?
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Post by extremeelle »

I see that this post dates back to 2012, but I am extremely interested in opening up the dialog again to see if anyone has any additional information. I've dealt with MC symptoms for many years even though I was diagnosed with CC only a couple years ago. While getting better over the past 8 mo or so on my elimination diet (as supported by Enterolab results), remission is still not in sight. The only course of action my GI doctor wants me to pursue is budesonide. After standing my ground on the diet approach, she referred me to an integrative medicine doctor - where I had an ah ha moment.

I lived in a sick house for three years (2003-2006). While there, I demolished a bathroom shower where the back walls were a thick blanket of Stachybotrys. I was directly breathing it in and had it all over me for 2 days. A few months later my (until then) clear health history took a nose dive. It started with a nose polyp, then uterine fibroids, nearly 20 cases of anaphylaxis that stopped as soon as I moved out of the house and sold everything, multiple uterine polyps, gut issues (years later diagnosed as CC), miscarriage, and infertility. I was about 29-32 at the time. Interestingly, I always new the anaphylaxis was beginning because in every case I would not only have the classic swollen tongue and lips and itchy head/skin, but I also started vaginal bleeding and had fecal incontinence. I asked multiple doctors about the latter two and they couldn't explain it. Now it is clearly that the toxins were working on my digestive and reproductive tracts too. The anaphylaxis also happened a lot on my runs so my allergist felt it was exercise induced. This angered me bc I had been running long distance for years with no issues. Now I know that the running and sweating process helps to detox so my system I was probably detoxing the most during my runs and the toxins were too much for my body.

I attributed all of these health issues to the mold except the gut issues. Now I realize that there are reports out there of Stachybotrys toxins negatively impacting the gut lining, etc. With the timing and all the other health issues I've struggled with post the mold exposure I'm certain that this was my MC trigger. I'm upset that I'm just now making the connection, but I finally feel that I am on the right path.

The integrative medicine doctor referred me to an environmental illness specialist to see if I still have a mycotoxin burden that is continuing to suppress my immune system. It will be an out-of-state phone consultation so I want to research before setting up an appointment. She'll probably start with mycotoxin testing from somewhere like Great Plains Labs to ensure that this is still an underlying factor. I have also learned that my genetics are such that I don't methylate or detox well (about six homozygous and heterozygous mutations in each profile), have a higher likelihood of celiacs disease, and am prone to IBS.

If anyone else has a similar mold exposure story that they feel was their trigger I would love to hear from you. In addition to mycotoxin testing and subsequent detox, I'm looking into EM 1, methylation treatment and other related topics that I would love to hear more about. My chiropractor has said that some of her methylation patients that have autoimmune diseases and are poor methylators have indeed gone into remission after the treatment started.
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