Impairment Of Intestinal Glutathione Synthesis With IBDs

Post by **tex** » Fri Apr 30, 2010 1:10 pm

http://gut.bmj.com/content/42/4/485.abstract

Zizzle · Post by **Zizzle** » Wed May 23, 2012 10:48 am

Tex,
I started reading about Glutathione for anti-aging properties, and was surprised to see the link to IBDs. Connie mentioned in a post that L Glutamine serves as a precursor to L Glutathione, but I'm not seeing much to support this. Are there other ways to increase our Glutathione levels safely? I'd love to look more youthful in the process too!! ALternatively, would a potent antioxidant like Asthaxanthin help with MC?

Here's what one supplement-maker has to say about Glutathione:

http://www.xtend-life.com/popup/ingredi ... hione.aspx

All this pill-popping makes me wish I could design my own MC supplement. I think it would contain:

calcium and magnesium citrate
D3
curcumin
l glutamine
zinc
ester-C
b-complex
fish oil or DHA supplement
Vit E maybe? Beta carotene?
and some potent antioxidant -- but which one??

Post by **tex** » Wed May 23, 2012 12:22 pm

We may become deficient in glutathione because of malabsorption issues that eventually lead to a deficiency of certain "B" vitamins, especially B-6, B-9, and B-12. Here's one individual's opinion on how to increase one's glutathione level:

http://inflammation911.com/7-natural-wa ... roduction/

Here's a more detailed discussion (that mentions B vitamins):

http://www.immune-health-solutions-for- ... hione.html

Tex

Zizzle · Post by **Zizzle** » Wed May 23, 2012 1:42 pm

Interesting. I suppose my L-glutamine powder is the only option right now, other than eating more green vegetables like broccoli, asparagus, avocado (staples of mine anyway). Never heard of the ammonia problem from storage before. New to you? Is taking capsule form safer than powder??

■Glutamine is an amino acid found in abundance in our body. It is tremendously beneficial to the body and is easily found in a healthy diet. Also, supplemental glutamine must be kept absolutely dry or it will degrade into ammonia, a toxin to the body. Due to its abundance in a healthy diet and the risks of storing it, glutamine is not an ideal supplement.

Post by **tex** » Wed May 23, 2012 1:51 pm

Hmmmmmm. No, I wasn't aware of a storage problem, but if it should begin to deteriorate, the odor should be obvious when you open the container. I don't have any experience with using or storing it, but I would think that capsules in a tightly closed bottle should remain a bit more stable than loose powder in the same bottle, due to the second barrier. It may not be a major problem -- Connie lives in the PNW (where it's almost always wet), and she's never complained of an ammonia problem.

Tex

Zizzle · Post by **Zizzle** » Wed May 23, 2012 1:58 pm

Yes, L-glutamine is odorless and tasteless, so I should be able to notice any changes. Makes me wish I hadn't just bought a huge tub! Maybe I'll store in multiple smaller containers. I suspect the avarage bodybuilder is not taking this into account either...

Zizzle · Post by **Zizzle** » Wed May 23, 2012 2:03 pm

Check out this totally unverifiable source of info. If all these things are true, everyone should be taking L-Glutamine!! The wetness factor is mentioned too.

http://www.sundancevideoonline.com/glutamine.html

Supplemental glutamine must be kept absolutely dry or the powder will degrade into ammonia and pyroglutamic acid.

Post by **tex** » Wed May 23, 2012 5:42 pm

That article appears to be valid. It's a shame that no references or even ID are listed.

Tex

wonderwoman · Post by **wonderwoman** » Wed May 23, 2012 11:47 pm

I have a large container of LG powder that I keep in the freezer. I transfer small amounts to another small container. I have never noticed an amonia smell. Don't know if it helps or not but I just keep taking it daily because I have it. The naturopath recommended it two years ago.