Diverticulitis and MC

[humbird753]

Hi - I tried doing a search on diverticulitis but didn't find the answer I was looking for.

I am wondering if diverticulitis/diverticulosis is associated with MC.

Any comments are appreciated.

Paula

[humbird753]

Tex - Is this "possible" connection noted in your book? I am reading it but am not done yet.

Thank you.

Paula

[tex]

Hi Paula,

I don't recall that I mentioned it in the book, (but I could be wrong — my memory certainly isn't perfect).

It's difficult to say that diverticulitis is directly associated with MC, but interestingly, it presents with the same type of inflammation pattern as LC, namely an increase in the number of mast cells, and increased lymphocytic infiltration. Of course, this is the same inflammation pattern that initiates celiac disease, and the other IBDs also, except that with the other IBDs, eosinophils are also present in large numbers.

http://www.docguide.com/role-colonic-ma ... ase?tsid=5

http://www.ncbi.nlm.nih.gov/pubmed/18347509

You're most welcome,
Tex

[Deb]

Paula, I've had issues with this and they have definitely improved as I've gone gluten-free. No more waking up in the middle of the night with pain. Deb

[JLH]

The pain from diverticulosis was the second thing that finally persuaded me to have my first colonoscopy four years ago.
I
have just recently been having that pain again and attribute it to not being able to have much fiber.