MC and SIBO dx behind IBS study!

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JLH
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MC and SIBO dx behind IBS study!

Post by JLH »

DISCLAIMER: I am not a doctor and don't play one on TV.

LDN July 18, 2014

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Zizzle
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Post by Zizzle »

Out of 132 IBS patients, only 3% (4 people) had MC?? That's surprisingly low. I tested borderline/negative for SIBO back when I got the MC diagnosis, but never got the actual results. Makes me wonder if we should get re-checked periodically??
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tex
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Post by tex »

Here's the original paper:

http://www.revmedchir.ro/pdf/RMC3_2012/18_mip_ao.pdf

The study was done in Romania. I don't understand why it was published as a pediatrics article, when the average age of subjects was 46.

Their diagnosis of MC may have been artificially low because they took biopsy samples from "normal" areas of mucosa, avoiding any areas that showed any indications of inflammation. IOW, they don't know how to diagnose MC.
During colonoscopy at least four biop-sies of normal mucosa from different re-gions of the colon were taken. Minimal macroscopic lesions (erythema, edema or superficial ulcers of mucosa) were noticed.
Areas of inflammation associated with MC are indeed visible, during a colonoscopy, contrary to the official description in the literature. Those ares are just not as prominent as areas of inflammation associated with Crohn's or UC. If they avoided those areas, then it's no wonder that they didn't discover many cases of MC. :roll:

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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