CC and LC differences

birdlover3 · Post by **birdlover3** » Sun Jan 20, 2013 3:25 pm

Is CC 'worse' than LC or vice versa? I've read up on it but nothing that really tells me if one is 'worse' than the other.

Post by **tex** » Sun Jan 20, 2013 3:38 pm

They're just different forms of the same disease. The clinical symptoms are the same, and the treatment is the same. The only difference is the way they are diagnosed. Everyone who has MC has increased mucosal lymphocytic infiltration, but those diagnosed with LC have a higher level of lymphocytic infiltration (IOW, a lymphocyte count that exceeds 20 lymphocytes per 100 enterocyte cells).

Those diagnosed with CC have increased thickness of collagen bands in their intestinal walls, (collagen bands that exceed 10 microns in thickness). With LC, collagen band thickness remains normal (IOW, below 10 microns in thickness). With CC, the lymphocyte count may or may not exceed 20 lymphocytes per 100 enterocytes — it's irrelevant, because the diagnosis of CC is based on the increased collagen band thickness.

In addition to LC and CC, there are at least 10 other forms of MC that most GI specialists have never even heard of.

Tex

birdlover3 · Post by **birdlover3** » Sun Jan 20, 2013 4:04 pm

WOW. Lots of language that I don't understand, but it appears that I don't need to ;)
Thanks for the knowledge.

Doug · Post by **Doug** » Sun Jan 20, 2013 5:26 pm

Yes it can be somewhat complex when you read up on it. Too much medical jargon.

Julie · Post by **Julie** » Mon Jan 21, 2013 4:25 pm

Thanks Tex!

I finally understand the difference now.

Julie