What do you think???

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tex
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Post by tex »

Yes, you obviously produce some level of IgA. Even those who have selective IgA deficiency produce some level of immunoglobulin A — they just aren't capable of producing an amount that is considered to be "normal", which causes IgA-based testing to yield erratic results.

In order to get a valid celiac blood test, you would have to eat gluten for at least 5 or 6 months (not the 1 or 2 months that many doctors clam is adequate), in order to cause enough small intestinal damage to trigger a positive test result. How could the results possibly be worth the misery?

On the other hand, it would be good to verify whether or not you have selective IgA deficiency, because if you do, it can contribute to various other health issues. And also, if you have selective IgA deficiency, the celiac blood tests are worthless anyway, so you would be doing a gluten challenge for nothing.

Also, remember that with or without selective IgA deficiency, some of us produce more immunoglobulin A than others, IOW antibody results will vary by the individual. All that the test to rule out selective IgA deficiency does is to verify that an individual is capable of producing a level of immunoglobulin A that is within an arbitrarily defined "normal" range. As Dr. Fine points out, antibody levels are not correlated with degree of sensitivity (because not everyone produces antibodies at equivalent rates).

When you do the colonoscopy, that will provide a good opportunity for biopsy evaluation, not only to check the status of your MC, but to include a stain for mast cells, also.

Love,
Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by Deb »

Tex, will you ever try dairy again? If not, why? Deb
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Post by tex »

Deb wrote:Tex, will you ever try dairy again? If not, why?
No, because I produce antibodies against casein. I never could verify that it contributed to my osteoarthritis, but I have a hunch that the reason why I couldn't is because it's such a long-term effect that it's difficult to measure without carefully calibrated lab testing.

I won't say that I don't miss it, but I have no problem living without it.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Kari
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Post by Kari »

Thanks for the clarifications and recommendations Tex. I have just switched health care providers, so I will be seeing a new GI doc. My GCP (who is open minded and supportive) recommended her, so I have some hope that she will be helpful.

Love,
Kari

P.S. LOL about the prep for the celiac test. At this point in time I would have to be slightly insane to purposely eat gluten :lol: .
"My mouth waters whenever I pass a bakery shop and sniff the aroma of fresh bread, but I am also grateful simply to be alive and sniffing." Dr. Bernstein
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