Feel free to discuss any topic of general interest, so long as nothing you post here is likely to be interpreted as insulting, and/or inflammatory, nor clearly designed to provoke any individual or group. Please be considerate of others feelings, and they will be considerate of yours.
This is the first study to find a positive association between antibiotic use and subsequent CD.
Antibiotic exposure was also linked to small-intestinal inflammation and to normal mucosa
with positive CD serology, both of which may represent early CD. The consistent association
between the multiple groups, the slightly stronger association between repeated use of
antibiotics compared with no use as well as the association with use of certain antibiotics
(e.g., metronidazole) and CD may suggest that antibiotic exposure, possibly through a
changed gut microbiota, plays a pathogenic role in early CD development. However, given
the lack of time-response effect, within the limited time window studied, we cannot rule out
non-causal explanations for our findings.
A severe reaction to an antibiotic prescribed for an ear infection precipitated MC. I imagine the celiac was triggered at the same time. I wonder why it happened that time and not years before when I took an antibiotic.
Sheila W
To get something you never had, you have to do something you never did.
A person who never made a mistake never tried something new. Einstein
Interesting. Some time ago I think I mentioned a study that found that kids who receive the most antibiotics for ear infections are at higher risk for developing IBDs. It's good that researchers are looking at antibiotics. Like Sheila, my MC/food sensitivities were precipitated by a 3 week course of an antibiotic (doxycycline) taken for suspected Lyme disease.
Sheila, not sure why. Maybe because different antibiotics target and wipe out different "good" gut bacteria. Or perhaps there is a "tipping point" that is reached, after which the bacteria can't recover to sufficient numbers.
Love,
Polly
Blessed are they who can laugh at themselves, for they shall never cease to be amused.
My daughter's first food reactions happened after a winter where she battled 4 bouts of strep throat. This past year, she only had strep and antibiotics once, and her pollen allergy and food reactions were much milder.
I think Polly is very probably right, our bodies reach a "tipping point" and flip the genetic switch for celiac and gluten intolerance into the on position.
When I was very young, about 65 years ago, when dinosaurs roamed the earth, I had my tonsils out. After the surgery I developed a mastoid infection which required penecillin shots every other day for a very long time. I was in agony with ear pain for most of summer school vacation and have had ear infections occasionally every since. I also had strep throat several times and pneumonia twice as a child requiring even more antibiotics. It was antibiotics for an ear infection that triggered the celiac and MC.
Sheila W
To get something you never had, you have to do something you never did.
A person who never made a mistake never tried something new. Einstein
Sheila, this is all very interesting. I had a lot of tonsil/strep throat issues as a child and asthmatic bronchitis.. My tonsils were removed when I was 16. I then, later, developed other auto-immune issues (eczema, endometriosis, allergies, MC, migraines, not sure if they're AI, etc.). I really wonder if I had eliminated gluten 50 years ago I may have avoided a lot of issues. Deb
