Microscopic colitis and fecal stream diversion

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gluten
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Microscopic colitis and fecal stream diversion

Post by gluten »

Hi, I found and interesting study. Type in the title of the post. They found that a noxious luminal factor is of pathogenetic importance. Jon
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tex
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Post by tex »

As discussed in my book, that old article (published almost 20 years ago) is rather misleading, since such surgery often does not work, due to small intestinal involvement in the reaction (the small intestine would also have to be removed to completely stop the reaction in those cases, and that would be fatal, of course). We have a member (actually her brother joined on her behalf) who allowed her doctors to talk her into having that surgery. The final result was no relief from the watery D, the added inconvenience of an ileostomy, and additional abdominal pain that didn't exist prior to the surgery (to say nothing of the risk involved and all the wasted money) — not exactly the outcome promised by that article.

The authors of more than a few of those old studies where such dramatically-successful results were obtained, apparently cherry-picked their subjects, in order to get the results they wanted to publish. :roll: The book also discusses several other misleading research reports (which interestingly, were also published during that same time frame).

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
gluten
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Post by gluten »

Hi Tex, Thanks for the information. I did not notice the date of the study until after I posted it. Jon
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Post by tex »

Jon,

I apologize. I didn't mean to imply that all older articles about MC are without merit, because that's certainly not true. Some of them are quite good. It may be just a coincidence that a number of research articles were published during the late 1990s that now appear to be very suspect (or downright wrong).

Even the the GI department of the Mayo Clinic advocates fecal stream diversion as a "cure" for refractory MC (MC that does not respond to treatment), but unfortunately, that particular research article appears to be the basis of their position, and that's a shame, because experience now shows that there is obviously a problem with the data used in the study, because the procedure does not bring anywhere near the success rate that is claimed in the article.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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