Tex, what is an Iga immune response?

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mcnomore
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Tex, what is an Iga immune response?

Post by mcnomore »

I was speaking with a functional doc that I am thinking of seeing and I told her I had an abnormal bm that was loose and yellowish. She said it sounded like an Iga immune response. I should have asked her what she meant, but she's not my doc yet so I didn't take up her time.

Hoping and suspecting you will know the answer. Thanks
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Leah
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Post by Leah »

Tex will give you a better, more thorough response, but when you are intolerant to a food, your body will produce IgA antibodies to help "fight off the invader". Too many antibodies sets off an inflammatory response. You know when some of us have done the Enterolab tests? The lab is looking for elevated IgA antibodies in the stool.
Does that help?

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tex
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Post by tex »

As Leah said, the type of antibodies that are related to digestive system reactions are known as IgA antibodies. These antibodies trigger the release of certain inflammation mediators in the gut, including the killer T cells that infiltrate the mucosa of the intestines. The presence of an elevated level of these T cells are used as diagnostic markers for LC. IgA antibodies can be found in stool, and in biopsy samples taken from the mucosa of the intestines. It typically takes the immune system several hours to a day or so to produce a significant IgA antibody response to a food sensitivity. IgA antibodies are used as the basis for the food sensitivity tests offered by EnteroLab.

IgE antibodies, by contrast, are involved with classic allergic responses, and these antibodies are produced within seconds to minutes of exposure to an allergen. IgE antibodies are found primarily in the skin and in the upper respiratory tract, and they typically trigger the release of histamine, cytokines, leukotrienes, etc., to cause upper respiratory responses, watery eyes, runny nose, throat congestion, rashes, hives, and in severe cases, anaphylactic symptoms.

When allergic reactions that result in IgE responses are allowed to continue on a long-term basis, they often result in the production of IgG antibodies. Therefore, IgG antibodies are considered to be a marker of a "mature" reaction.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by mcnomore »

My thanks to both you.
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Post by mcnomore »

I guess it means that I am still eating something I shouldn't. Why would I have this sort of reaction only once every 10 days or so?
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Post by Leah »

I would keep a food diary for a few weeks. Maybe a pattern will emerge
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Post by tex »

mcnomore wrote:Why would I have this sort of reaction only once every 10 days or so?
My MC reactions cycled about every 10 to 15 days, or so. Or maybe the reactions are due to a histamine buildup. At any rate, as Leah suggested, keeping a food diary might reveal some clues.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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