This certainly is not the most earth-shattering question I've asked here, but I want some opinions.
I recently tried Nortriptyline to see if it managed my motility issues as well as Amitriptyline (it didn't). On Nortriptyline I was in a better mood and more relaxed, but my gut was rocking and rolling. I ended up taking an Imodium or two just to slow down the motility action, 3 times in 9 days. That seemed silly to continue that way so I went back to Amitriptyline (trying a smaller dosage).
On Nortriptyline I had a lot of gurgling. I know one time was the result of eating Tostitos and I figured maybe the grease was getting to me. But it made me wonder..... am I still reacting to something and the Amitriptyline is masking it?
Or am I quieter on Amitriptyline just because motility is slowed.
Is it possible to still be reacting and Amitriptyline is masking it?. I really dont' want that. Probably this summer when I'm not working I may just stop Amitriptyline and see how I am without any med.
Carol
BTW-- I have felt very good this week. Minimal gurgling, quiet gut, Norman shows up every day. I'm hoping I'm finally over the soy 'poisoning' I had due to supplements and the lower Amitriptyline dosage is better for me.
Gurgling is a sign of _____?
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
Gurgling is a sign of _____?
“.... people will forget what you said, people will forget what you did, but people will never forget how you made them feel.” Maya Angelou
Carol,
That's a very good question, and I wish I knew the answer.
I would be inclined to think that rather than the amitriptyline masking a food problem, the nortriptyline was probably causing a drug-induced reaction. As you're well aware, nortriptyline is a second generation tricyclic antidepressant — it's a metabolite of amitriptyline. I'm not sure how it compares with amitriptyline regarding it's antihistamine properties, but perhaps it's too much of a good thing.
Or maybe it's missing something that makes amitriptyline effective for you.
And as always, there's a good chance that the reaction might be caused by one or more of the inactive ingredients.
Still, you shouldn't need a medication for normal BMs, so there's certainly a possibility that the amitriptyline might be masking something, and there's a good chance that histamine is involved, since the tricyclic antidepressants are such powerful antihistamines.
Tex
That's a very good question, and I wish I knew the answer.
I would be inclined to think that rather than the amitriptyline masking a food problem, the nortriptyline was probably causing a drug-induced reaction. As you're well aware, nortriptyline is a second generation tricyclic antidepressant — it's a metabolite of amitriptyline. I'm not sure how it compares with amitriptyline regarding it's antihistamine properties, but perhaps it's too much of a good thing.
Or maybe it's missing something that makes amitriptyline effective for you.And as always, there's a good chance that the reaction might be caused by one or more of the inactive ingredients.
Still, you shouldn't need a medication for normal BMs, so there's certainly a possibility that the amitriptyline might be masking something, and there's a good chance that histamine is involved, since the tricyclic antidepressants are such powerful antihistamines.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Thanks Tex. As I get past spring allergies and off work in early June, I do think I'll just stop the Amitriptyline and see what happens. Polly and I had theorized that my motility issues might be histamine or even mast cell related. If I get the Amitriptyline out of the way I might be able to sort this out probably with a good old fashioned food log. As we all know, stress is the wild card. I think I can do better detective work when I have a little more control over my schedule. I know that at this point the full dose of Amitriptyline seems like too much and it slows my motility too much.
thanks, as always, for your thoughts.
Carol
thanks, as always, for your thoughts.
Carol
“.... people will forget what you said, people will forget what you did, but people will never forget how you made them feel.” Maya Angelou