Anyone's symptoms worse at night? or morning?

[Toritagg]

Currently-- I seem to be "ok" during the day...although I sort of feel a bit of C the whole day.... First thing in the morning I have D and then the rest of the day goes well until night time about an hour before I sleep-- the bloating builds and builds all day and evening and then I have horrible bloating and horrible gas. :( Then the entire sequence starts again the next day. Is this normal? And I am worried about taking budesonide bc I don't want it to make the C even worse... and if the D is only in the morning... do I need the budesonide?

[nerdhume]

My symptoms seem worse at night when I am trying to sleep, seems like it builds during the day.

[CathyMe.]

Currently-- I seem to be "ok" during the day...although I sort of feel a bit of C the whole day.... First thing in the morning I have D and then the rest of the day goes well until night time about an hour before I sleep-- the bloating builds and builds all day and evening and then I have horrible bloating and horrible gas. :( Then the entire sequence starts again the next day. Is this normal? And I am worried about taking budesonide bc I don't want it to make the C even worse... and if the D is only in the morning... do I need the budesonide?

Hi there,
When I was at my worst, the explosive D happened throughout the day but was worst 1st thing in the morning. I would also have an "episode" 4-5 times a week after work while walking my dogs. It's up to you whether you want/need to take budesonide. I had no choice as my W and ED was making it difficult to leave my house without worrying about having an accident. It was a lifesaver to me and I never got to the point of C.

[Zizzle]

I'm generally worse at night, but I think that's because I have my largest meal of the day at night when I'm home, so I tend to pig out!

[Gabes-Apg]

In line with some of the other responses;

I only have issues during the night if I have a large meal after 5pm or if I eat too close to going to bed.
even prior to the MC Dx, having my main meal in the middle of the day meant I slept better.

MC wise, mornings are the best time for me ( it is the Fibromyalgia and other health issues that create symptoms in the AM)

If I happen to have a particularly stressful day at work etc, then there would be MC Mud issues around 6pm.

If you keep a food/activity/symptom journal this may help to identify the activity or reason for exacerbated symptoms.

[coryhub]

I'm always on the toilet in the morning. The rest of the day and evening go by better. As for Budesonide, when I have a flare I can't get under control and I find myself frustrated in tears - then it's time to get on the pills.
Cory

[Sheila]

Yes, I seem to be more bloated, gassier at night than during the day. The bm's start 5-6 a.m., Normans for the most part, and I'm done for the day by about 7 a.m. While on budesinide I also had more gas and belching at night after dinner. Last night for the first time since stopping budesinide, I was doubled over with gas pains immediately after finishing dinner. Several huge belches later, the pain was gone. I'm re-evaluating all my food choices and keeping a food diary again. I'm seriously thinking of taking the Enterolab test again to see if anything has changed. I would love to be able to eat eggs again.

I don't take a budesinide when I'm in a flare because, as Tex informed us recently, the more frequently you take budesinide the more likely you are to have bone loss. It doesn't seem to cause much loss the first time it is taken but when taken repeatedly, bone loss occurs.

Sheila W

[tex]

Hi Sheila,

I may have not done a good job of explaining, and consequently you may have misunderstood what I was trying to say. Yes, the free pass only applies to the first time we use budesonide, but after that, any reuse should carry basically the same risk of bone loss, the risk does not increase with repeated uses. And the main point is that the potential for bone loss is always much lower with budesonide, than it is when compared with any other corticosteroid.

Also, remember that bone loss is a dosage and time-dependent event (that is, the potential for bone loss depends on the budesonide dose and on the length of the treatment program). IOW, short-term exposure to budesonide should result in an insignificant risk of bone loss. It's extended treatment periods, at higher dosage rates, that carry a significant risk of bone loss, and even then, as I mentioned, that risk is still much lower than it would be with prednisone, for example.

The greatest risk with repeated retreatments is a possible progressively-declining efficacy with subsequent treatment regimens.

Tex

[Sheila]

Thank you, Tex. I certainly did misunderstand your explanation. Going back on budesinide is not something I want to do despite the very low dose, 3 mg every third day. There is a very definite improvement in overall well-being for me when on budesinide. I didn't realize just how much it protected me from the small amount of soy or dairy that slipped into my diet. I could eat a few tablespoons of parmesan cheese and have no reaction while on budesinide. However, injesting a steroid, no matter how small a dose, is not a good idea over the longterm unless there is no other option. I'm hoping things will get better over time.

Thanks again, Tex for the clarification.

Sheila W