celiac/neurologic/brain connection

Feel free to discuss any topic of general interest, so long as nothing you post here is likely to be interpreted as insulting, and/or inflammatory, nor clearly designed to provoke any individual or group. Please be considerate of others feelings, and they will be considerate of yours.

Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh

Post Reply
Hopeful
Adélie Penguin
Adélie Penguin
Posts: 227
Joined: Mon Sep 08, 2014 5:24 pm

celiac/neurologic/brain connection

Post by Hopeful »

Fascinating article in the NY Times.
Excerpt:
Armin Alaedini, an immunologist now at Columbia University, found that antibodies directed at gliadin, a gluten protein, could cross-react with proteins in the brain. The finding suggests that, by some coincidence, certain proteins on neurons structurally resemble proteins in wheat. Meaning that, if your immune system attacks gluten, it might also inadvertently pursue brain tissue.

This discovery has helped revive an old idea about schizophrenia. Might an immune reaction to wheat contribute in some cases? In 2011, Johns Hopkins University scientists found that nearly one-quarter of serum samples from some 1,400 schizophrenia patients had anti-gliadin antibodies, compared with just 3 percent of healthy controls. Of the subset with those antibodies, one-fifth also had those antibodies to transglutaminase 6 linked with neurological dysfunction, compared with 6 percent of healthy controls.

Link to whole article:
http://www.nytimes.com/2014/10/12/opini ... egion&_r=0
User avatar
Gabes-Apg
Emperor Penguin
Emperor Penguin
Posts: 8332
Joined: Mon Dec 21, 2009 3:12 pm
Location: Hunter Valley NSW Australia

Post by Gabes-Apg »

The other link to this is leaky gut, toxins /metals are not cleared from the gut properly and end up via leaky gut in the blood stream and then the toxins/metals 'hang out' in the brain. (reason for brain fog, headaches, depression/anxiety, etc etc)

for those with Methylation issues (MTHFR Pyrrole) the cells are not equipped with the right nutrients/minerals to clear these metals from the brain.
(Things like Pyrrole gene mutation were found when psychiatrists were trying to figure out why medications were not working for schizophrenia. )

This is why alot of the depression/anxiety medications do not work for 10-20% of the population, the medication makes the toxin/metal toxicity in the brain worse.
(when the solution is change diet, fix the gut, get the right supps to clear the toxins/metals)

While ever people keep eating processed, high carb, high sugar, high fat foods, ignore IBS/IBD symptoms, the process of leaky gut, increased toxins/metals, increasing levels in the brain will continue to happen.

This is also why even if you dont have the celiac gene, gluten is a high inflammatory food that does cause damage to the gut, for those with other health issues, consuming gluten will increase the risk of neurological / nervous system issues.
Gabes Ryan

"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
User avatar
tex
Site Admin
Site Admin
Posts: 35071
Joined: Tue May 24, 2005 9:00 am
Location: Central Texas

Post by tex »

Hopeful,

That article presents the information as if it's a new/recent concept, but Dr. Hadjivassiliou (in England) is a pioneer in this field of research, and he was publishing research articles on the neurological effects of gluten over 12 years ago. Unfortunately most neurologists still continue to ignore it, but hopefully they will update their training procedures and become aware of this information within the next decade or 2. :lol: You might be interested in this article as background information:

Gluten sensitivity as a neurological illness

Thanks for the link.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
User avatar
Zizzle
King Penguin
King Penguin
Posts: 3492
Joined: Thu Jul 22, 2010 9:47 am

Post by Zizzle »

I think mental health treatment hospitals should serve GF/DF foods at all patients with schizophrenia, autism and related disorders.
1987 Mononucleosis (EBV)
2004 Hypomyopathic Dermatomyositis
2009 Lymphocytic Colitis
2010 GF/DF/SF Diet
2014 Low Dose Naltrexone
Post Reply

Return to “Main Message Board”