CC and broadspectred antibiotics

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Lilja
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CC and broadspectred antibiotics

Post by Lilja »

Hi,

I need some advice.

I'm currently on Entocort. I have today been to the dr who removed an abcsess in my arm. It was so infected that he had to remove it by knife and empty it (a lot of pus) , and then put a tampon in there, to be removed and taken care of tomorrow.

He insisted that I took a broadspectred antibiotic, called Diclocil (Dikloxacillin) here in Norway. I reminded him that I have CC and am currently on Entocort, but he said there was no way around it. (I need to say that I suspect that the root cause of my CC is/was overuse of antibiotics).

I am worried, and wonder if I will be brought back to square 1 as to my CC, if I take the Diclocil, 30 capsules in all. He said that it was even more important that I take the antibiotics now, since I'm on immunosuppresive medication.

What can I do to minimize the eventual harm that the Diclocil will do, other than taking lacto acid bacteria tablets?

I would appreciate to hear your opinion on this :sad:

Lilja

PS: My B12, D3 and thyroid levels were good. "It's rare to see such excellent values in a 67 year old person", he said. That is always something!
Collagenous Colitis diagnosis in 2010
Psoriasis in 1973, symptom free in 2014
GF, CF and SF free since April, 2013
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tex
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Post by tex »

Hi Lilja,

Unfortunately we are not immune to the same medical ailments that many other people have to deal with occasionally, so sometimes we have to choose to take treatments that we know may have bad consequences for MC, because not taking the treatment could be dangerous for our overall health.

You are doing about all that you can do under the circumstances. Be sure to continue to take the probiotic for at least 2 weeks after you have finished the antibiotic treatment.

If you have taken that probiotic before, and you tolerate it well, then that is probably the best that you can do. If it seems to cause you to react after you begin taking it, you might try another brand or another type of probiotic.

Good luck with this. I hope that it doesn't cause any major symptoms.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Lilja
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Post by Lilja »

tex wrote:Hi Lilja,

Unfortunately we are not immune to the same medical ailments that many other people have to deal with occasionally, so sometimes we have to choose to take treatments that we know may have bad consequences for MC, because not taking the treatment could be dangerous for our overall health.


Good luck with this. I hope that it doesn't cause any major symptoms.

Tex
Thank you, Tex. I was thinking out loud here, after the visit to the doctor:

1) The Staphylococcus aureus have been there for at least 2 years (discovered for the first time in a brain-scan, as "a water assembly" behind my right ear), a brain scan I wanted to do, due to my confusion and drunkman gait

2) I have autoimmune diseases (psorasis and CC)

3) The Staphylococcus aureus has until now been suppressed by my overactive immune system

4) Now that I'm taking immunosuppresive medications (Entocort), the Staphylococcus aureus is no longer suppressed by my overactive immune system, and it manifests itself in the form of a lump in my arm full of Staphylococcus aureus.

Is this a valid theory, in your opinion?

Lilja
Collagenous Colitis diagnosis in 2010
Psoriasis in 1973, symptom free in 2014
GF, CF and SF free since April, 2013
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Post by tex »

Lilja,

Your thinking is right in line with mine. Whenever we use immune system suppressants, we raise our risk of infections. Usually, we can get away with it, but sometimes we can't. This is the reason why the labels on the anti-TNF immune system suppressants warn against using them if a patient has tuberculosis or any infections, because those infections can only become worse as the immune system is suppressed.

Most of us carry Staph bacteria in our nose, for example, at one time or another, and many of us carry them at all times. And of course they are always looking for an opportunity to become better established.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Trigger2298
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Post by Trigger2298 »

I wish you the best lilja..antibiotics use just scares me and its all way above my knowledge which complicates things more for me... MC and what comes with is just so overwhelming to me and all of us but you sound like you have a good grasp on things and you're in good hands with Tex and all the other generous and knowledgeable posters giving their time here.
Lilja
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Post by Lilja »

Since it is Saturday and my dr is not working, I had to go to ER today to clean more pus out of the wound. The doctor there told me that they never give antibiotics in cases like mine. That was a big disappointment to me, but I guess my dr knows what he is doing, and maybe this one wasn't aware of the fact that I have Staph.

I'm so lucky to have you guys to guide me!

Lots of thank you and hugs to all of you, especially to Tex :grin:

Lilja
Collagenous Colitis diagnosis in 2010
Psoriasis in 1973, symptom free in 2014
GF, CF and SF free since April, 2013
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Post by tex »

Lilja

Maybe your doctor is just being cautious.

When I was recovering from abdominal surgery a few years ago, a few days after my stitches were removed, I bent over to pick up something that had fallen on the floor. About 3 cm of the partially-healed incision popped open, and a lot of foul-smelling bloody juice ran out. When I called the surgical followup team, they told me to come to the hospital, and they would check it. Since the rest of it seemed to be healing OK, they showed me how to pack the cavity with gauze, and then cover it with a loose bandage (just to keep the fluids from getting on my clothes). I did that twice a day for a couple of weeks (first thing in the morning, and again at bedtime), and then for about a week I only repacked it at bedtime, and the cavity slowly grew smaller and smaller, until finally it was too small to pack. It healed fine.

No one ever mentioned an antibiotic.

Thanks for the hugs. I hope you're feeling better today.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by tex »

Lilja

Maybe your doctor is just being cautious.

When I was recovering from abdominal surgery a few years ago, a few days after my stitches were removed, I bent over to pick up something that had fallen on the floor. About 3 cm of the partially-healed incision popped open, and a lot of foul-smelling bloody juice ran out. When I called the surgical followup team, they told me to come to the hospital, and they would check it. Since the rest of it seemed to be healing OK, they showed me how to pack the cavity with gauze, and then cover it with a loose bandage (just to keep the fluids from getting on my clothes). I did that twice a day for a couple of weeks (first thing in the morning, and again at bedtime), and then for about a week I only repacked it at bedtime, and the cavity slowly grew smaller and smaller, until finally it was too small to pack. It healed fine.

No one ever mentioned an antibiotic.

Thanks for the hugs. I hope you're feeling better today. :grouphug:

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Lilja
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Post by Lilja »

tex wrote:Lilja

Maybe your doctor is just being cautious.

When I was recovering from abdominal surgery a few years ago, a few days after my stitches were removed, I bent over to pick up something that had fallen on the floor. About 3 cm of the partially-healed incision popped open, and a lot of foul-smelling bloody juice ran out. When I called the surgical followup team, they told me to come to the hospital, and they would check it. Since the rest of it seemed to be healing OK, they showed me how to pack the cavity with gauze, and then cover it with a loose bandage (just to keep the fluids from getting on my clothes). I did that twice a day for a couple of weeks (first thing in the morning, and again at bedtime), and then for about a week I only repacked it at bedtime, and the cavity slowly grew smaller and smaller, until finally it was too small to pack. It healed fine.

No one ever mentioned an antibiotic.

Thanks for the hugs. I hope you're feeling better today. :grouphug:

Tex
Thank you, Tex.
They gave me a water-syringe, to fill with water and clean the wound twice a day, and then cover it with gauze. Since the tampon they removed was quite stuck and hard to pull out, I think that the wound is healing already and that the pus has disappeared. They said I could use tap water (yes we have good water, but come on... ), but I think I will add some Klorhexidine to it, to be on the safe side. Loose bandage is smart, to let air into it and let the wound "breathe".

So far so good!

Remains to be seen how my body reacts to 8 days of Diclocil, but that is a worry I will deal with when/if it raises.

Lilja

PS: Thank you for advising me to continue the probiotic regime after having stopped the Diclocil medication. I think that is a very good idea :smile:
Collagenous Colitis diagnosis in 2010
Psoriasis in 1973, symptom free in 2014
GF, CF and SF free since April, 2013
Lilja
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Post by Lilja »

Hi,

I wonder why the pain in my legs, hips, groin and lower back have come back again. I can't remember that I had them after restarting Entocort in October. Could it be the Diclocil antibiotics I started last Friday?

If so, would that be a sign of the antiobiotics fightingt an (unknown) inflamation in my legs etc., or do the Entocort and the Diclocil "sabotage" each other?

Ohhh, I wish the pain would go away! It is so debilitating, and I need to be pain free now that December is approaching (as we all do).

Does anyone have a clou?

Lilja
Collagenous Colitis diagnosis in 2010
Psoriasis in 1973, symptom free in 2014
GF, CF and SF free since April, 2013
BearcatRx
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Post by BearcatRx »

It is my professional opinion that Entocort would most likely NOT be the cause of S. aureus growing out of control and this serious infection to show up. It's an enteric coated capsule with minimal systemic absorption. This means only a small amount actually gets into the blood stream. If you were taking a systemic corticosteroid such as prednisone on a daily basis then I would definitely point thing finger at that.
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Post by BearcatRx »

Lilja wrote:Hi,

I wonder why I the pain in my legs, hips, groin and lower back have come back again. I can't remember that I had them after restarting Entocort in October. Could it be the Diclocil antibiotics I started last Friday?

If so, would that be a sign of the antiobiotics fightingt an (unknown) inflamation in my legs etc., or do the Entocort and the Diclocil "sabotage" each other?

Ohhh, I wish the pain would go away! It is so debilitating, and I need to be pain free now that December is approaching (as we all do).

Does anyone have a clou?

Lilja
Lilja,

I've never heard of nor seen an antibiotic actually causing any sort of pain or discomfort aside from the typical GI upset, diarrhea, nausea, etc. At least not in this drug class. There are a few antibiotic that can cause tendon rupture and muscle aches as a side effect, but this is not one. Dicloxacillin is a form of penicillin active against MSSA. Also, running an interaction report shows no DDI between Entocort and Dicloxacillin.
Lilja
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Post by Lilja »

BearcatRx wrote:
Lilja wrote:Hi,

I wonder why I the pain in my legs, hips, groin and lower back have come back again. I can't remember that I had them after restarting Entocort in October. Could it be the Diclocil antibiotics I started last Friday?

If so, would that be a sign of the antiobiotics fightingt an (unknown) inflamation in my legs etc., or do the Entocort and the Diclocil "sabotage" each other?

Ohhh, I wish the pain would go away! It is so debilitating, and I need to be pain free now that December is approaching (as we all do).

Does anyone have a clou?

Lilja
Lilja,

I've never heard of nor seen an antibiotic actually causing any sort of pain or discomfort aside from the typical GI upset, diarrhea, nausea, etc. At least not in this drug class. There are a few antibiotic that can cause tendon rupture and muscle aches as a side effect, but this is not one. Dicloxacillin is a form of penicillin active against MSSA. Also, running an interaction report shows no DDI between Entocort and Dicloxacillin.
Thank you BearcatRX. If it is not Entocort or Diclocil, it is perhaps the food. But, I have not changed my diet or had any "mishappenings".

One of life's (or illness') mysteries. :smile:
Lilja
Collagenous Colitis diagnosis in 2010
Psoriasis in 1973, symptom free in 2014
GF, CF and SF free since April, 2013
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tex
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Post by tex »

Hi Lilja,

I agree with Bearcat's post about your recently resuming taking Entocort not being the likely cause of your staph infection. However, since research shows that up to 19 % of the budesonide in Entocort can be absorbed into the bloodstream, that's enough to eventually cause systemic issues. The reason I mention this is because I don't recall how long you took Entocort back when it was first prescribed, but it's possible that if you took it for several months or more, that might have contributed to a previous episode where Staph bacteria became better established, thereby making it easier for them to establish a secondary infection. But still, I doubt that you have been taking Entocort long enough to cause that problem with your current treatment program.

And of course Bearcat is quite correct that the antibiotic you are taking isn't likely to be causing the pains that you are experiencing. However, that doesn't mean that the Entocort couldn't be causing those pains. You may have mistakenly assumed that after reading his posts, but that's not what he said. He just said that it isn't likely that the antibiotic is responsible for causing those symptoms. Here is a relatively comprehensive list of the possible side effects known to be associated with taking Entocort. I have highlighted in red, all the listings for pain.
You should check with your doctor immediately if any of these side effects occur when taking budesonide:
More common


Bruising easily
chills
colds
cough or hoarseness
fever
flu-like symptoms
sneezing
sore throat

Less common

Abdominal or stomach pain
bladder pain
bleeding after defecation
bloody or cloudy urine
blurred vision
burning while urinating
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain
convulsions
cough producing mucus
decreased urine
diarrhea
difficult or labored breathing
difficult or painful urination
dizziness
dry mouth
eye pain
fast, irregular, pounding, or racing heartbeat or pulse
feeling of warmth
general feeling of discomfort or illness
headache
heartburn
increase in body movements
increased thirst
increased urge to urinate during the night
irregular heartbeat
joint pain
loss of appetite
lower back or side pain
mood changes
muscle aches and pains
nausea or vomiting
nervousness
numbness or tingling in the hands, feet, or lips
pain or discomfort in the chest, upper stomach, or throat
pounding in the ears
rectal bleeding
redness of the face, neck, arms, and occasionally, upper chest
runny nose
severe constipation
shakiness in the legs, arms, hands, or feet
shivering
slow or fast heartbeat
stomach cramps
sweating
swelling of the legs and feet
swelling or puffiness of the face
tightness in the chest
trouble sleeping
uncomfortable swelling around the anus
unusual tiredness or weakness
upper abdominal or stomach pain
waking to urinate at night
weight gain
weight loss

Incidence not known

Bulging soft spot on the head of an infant
change in the ability to see colors, especially blue or yellow
difficulty with swallowing
hives
itching
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
skin rash

Some of the side effects that can occur with budesonide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
More common

Acid or sour stomach
belching
blemishes on the skin
heartburn
indigestion
pain or tenderness around the eyes and cheekbones
pimples
rounded or moon face
stomach discomfort, upset, or pain
stuffy nose

Less common

Accumulation of pus
agitation
blistering, crusting, irritation, itching, or reddening of the skin
bloated or full feeling
change in hearing
changes in vision
cracked, dry, or scaly skin
cracks in the skin at the corners of mouth
difficulty having a bowel movement (stool)
difficulty with moving
dizziness or lightheadedness
ear drainage
earache or pain in the ear
excess air or gas in the stomach or intestines
feeling of constant movement of self or surroundings
hair loss or thinning of the hair
increased appetite
increased hair growth, especially on the face
lack or loss of strength
loss of memory
muscle pains or stiffness
nervousness
pain, swelling, or redness in the joints
passing gas
pinpoint red or purple spots on the skin
pressure in the stomach
problems with memory
redness, swelling, or soreness of the tongue
sensation of spinning
skin rash
skin rash, encrusted, scaly, and oozing
sleepiness or unusual drowsiness
sleeplessness
soreness or redness around the fingernails and toenails
swelling of the abdominal or stomach area
swollen joints
unable to sleep
uterine bleeding between menstrual periods
Entocort EC Side Effects

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
BearcatRx
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Post by BearcatRx »

tex wrote:But still, I doubt that you have been taking Entocort long enough to cause that problem with your current treatment program.
Correct indeed. I wouldn't put a time limit on it, but generally speaking you don't see any major side effects from corticosteroids for at least several weeks and potentially even longer for immunosuppression.
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