Tex
This Just Dawned On Me :shock:
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Thanks. Now I remember you mentioning that previously. I was just wondering if doc Fasano had considered genetic restraints. Apparently he probably did. If he had pronounced you a celiac in the absence of one of the main celiac genes, that would have been a real eye-opener.
Tex
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
I completely agree with "enterocolitis". In fact, the gastroscopy that I had last spring because of symptoms in my throat revealed oral thrush, esophagitis, and esophageal spasms a few months before I started developing abdominal pains and diarrhea. I am convinced that it is all connected.
Medscape just had information about IBD this week: Inflammatory Bowel Disease: More than a Gut Feeling
Unfortunately, very disappointing information, nothing alluding to diet.
Microscopic colitis is a chronic, inflammatory colon disease characterized by chronic watery diarrhea. It has 2 subtypes, collagenous and lymphocytic,[10,11] with estimated annual incidences of 1.1-5.2 and 3.1-5.5 per 100,000, respectively.[12] Mean age at diagnosis of microscopic colitis is ~65 years. There is a female preponderance, apparently more pronounced in lymphocytic than in collagenous colitis. In addition to the chronic watery diarrhea,[10] microscopic colitis is associated with fecal urgency, incontinence, nocturnal episodes and abdominal pain. There may be weight loss from fluid loss or decreased oral intake. Colonoscopy usually shows normal mucosa. The diagnosis is established by means of histology. Collagenous colitis is characterized by a colonic subepithelial collagen band greater than 10 µm in diameter (shown). Lymphocytic colitis is characterized by ≥20 intraepithelial lymphocytes (IELs) per 100 surface epithelial cells.[10] Crypt architecture is usually not distorted, but focal cryptitis may be present.
Antidiarrheals may be used alone in patients with mild diarrhea. Budesonide 9 mg/day is the treatment of choice for patients with microscopic colitis who have active disease. In patients who do not respond to budesonide, concomitant therapy with cholestyramine or bismuth subsalicylate alone can be administered. Anti-TNF agents are indicated for refractory disease.[13] Surgery is reserved for patients with microscopic colitis that is refractory to medical therapy.
Medscape just had information about IBD this week: Inflammatory Bowel Disease: More than a Gut Feeling
Unfortunately, very disappointing information, nothing alluding to diet.
Microscopic colitis is a chronic, inflammatory colon disease characterized by chronic watery diarrhea. It has 2 subtypes, collagenous and lymphocytic,[10,11] with estimated annual incidences of 1.1-5.2 and 3.1-5.5 per 100,000, respectively.[12] Mean age at diagnosis of microscopic colitis is ~65 years. There is a female preponderance, apparently more pronounced in lymphocytic than in collagenous colitis. In addition to the chronic watery diarrhea,[10] microscopic colitis is associated with fecal urgency, incontinence, nocturnal episodes and abdominal pain. There may be weight loss from fluid loss or decreased oral intake. Colonoscopy usually shows normal mucosa. The diagnosis is established by means of histology. Collagenous colitis is characterized by a colonic subepithelial collagen band greater than 10 µm in diameter (shown). Lymphocytic colitis is characterized by ≥20 intraepithelial lymphocytes (IELs) per 100 surface epithelial cells.[10] Crypt architecture is usually not distorted, but focal cryptitis may be present.
Antidiarrheals may be used alone in patients with mild diarrhea. Budesonide 9 mg/day is the treatment of choice for patients with microscopic colitis who have active disease. In patients who do not respond to budesonide, concomitant therapy with cholestyramine or bismuth subsalicylate alone can be administered. Anti-TNF agents are indicated for refractory disease.[13] Surgery is reserved for patients with microscopic colitis that is refractory to medical therapy.
TNF drugs...interesting. More evidence that MC is autoimmune.
Patricia, how are you treating the thrush? I recently took a couple months of Nystatin pills for intestinal candidiasis, and my daughter has just begun, but from what I read it will be a long, complex journey trying to keep the yeast under control.
Patricia, how are you treating the thrush? I recently took a couple months of Nystatin pills for intestinal candidiasis, and my daughter has just begun, but from what I read it will be a long, complex journey trying to keep the yeast under control.
1987 Mononucleosis (EBV)
2004 Hypomyopathic Dermatomyositis
2009 Lymphocytic Colitis
2010 GF/DF/SF Diet
2014 Low Dose Naltrexone
2004 Hypomyopathic Dermatomyositis
2009 Lymphocytic Colitis
2010 GF/DF/SF Diet
2014 Low Dose Naltrexone
I was not even aware of the oral thrush at the time (I could not see it myself, I think it must have been pretty far back in my mouth/top of the esophagus). When I asked them what caused it, they thought that it was the combination of Nasonex (for the seasonal allergies in spring) and the PPI that they had put me on for a week to see if my "lump in my throat feeling" would go away. When the PPI did not do anything at all for me they decided on the gastroscopy and found the thrush and the other things (also polyps in my stomach, that they thought were also due to the PPI). The gastroenterologist prescribed Fluconazole (Diflucan), 100 mg tablets, for the thrush. I had to take 2 tablets the first day, 1 tablet on days 2 through 10. My gastroenterologist said that this would take care of it and I wouldn't need to do anything else. I hope it took care of it, but I honestly don't know since I was never able to see it myself.