More On Fecal Transplants For IBDs

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tex
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More On Fecal Transplants For IBDs

Post by tex »

Hi All,

Another study has been released showing that fecal transplant therapy is ineffective for ulcerative colitis.
Fecal microbiota transplantation was not more effective compared with placebo in patients with active ulcerative colitis, according to research presented at the 10th Congress of ECCO in Barcelona, Spain
FMT not effective in active UC patients

This supports my long-held opinion that fecal transplants are not likely to be effective for MC, unfortunately.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Gabes-Apg
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Post by Gabes-Apg »

the more I read about methylation and cell health - not only would you need both the donor and the recipient need to have good dental health, reasonable gut health, minimal leaky gut etc, both would need to be free of excess toxins/metals, minimal deficiencies in their cells etc. to optimise any success with something like this ....
Gabes Ryan

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Post by nerdhume »

what about this:
http://www.medicalnewstoday.com/articles/289085.php
it would be interesting to know why the fecal transplant caused obesity.
Theresa

MC and UC 2014
in remission since June 1, 2014

We must all suffer one of two things: the pain of discipline or the pain of regret. ~Jim Rohn
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tex
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Post by tex »

Hi Theresa,

That happened because a certain strain (or strain) of bacteria from the donor managed to attach to the intestinal wall of the recipient and establish a thriving colony. Research data were published several years ago describing how certain gut bacteria are able to promote obesity. Of course no one knows exactly how they do this, but they may do it by producing enzymes that are capable of expressing certain hormonal receptors that can alter the response of genes associated with thyroid function (which controls metabolism) or by altering metabolism directly. At any rate, they are apparently capable of altering metabolism to promote obesity, and they can frustrate diet plans.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by Vanessa »

Just as I was getting sick with CC a year ago, I was set to be a fecal donor for my brother who was suffering with antibiotic induced c-diff. Since I had not been diagnosed yet and was not having problems until the week of the transplant, it was set to go and it took care of his c-diff that very day. He had a very bad acute case of diverticulitis that required surgery, and of course the ten rounds of antibiotics to try and correct the problems that ensued. I'm still fascinated that I was a fecal donor and now I feel sick as hell! I tease him that I want my poop back :lol: it is also interesting to note that ever since, my gas has not had a smell and my brother tells me that he now has my "brand" of gas. I tell him it's pay back for all of the big brother things he did to me. :pigtail: he also noted that over the course of the week he received my donation,the eczema on his hands cleared up like they never had before. I worry down the road that he will develop my disease. Hopefully since it has been over a year and he has had no problems we're in the clear!
Vanessa
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Post by tex »

Vanessa,

That's an interesting post, especially the observation about the eczema responding. I'm guessing that the treatment worked so rapidly because your immune system was in overdrive at the time, so presumably some of those antibodies to gut pathogens in your stool were transferred to him, and they kicked his immune system up a notch or 2 also.

Hopefully, that early in the development of MC, your antibody levels to your current food sensitivities were not high enough to trigger a response from his immune system. Of course with similar genetics, it's always possible that he might someday develop MC, but if that happens, it probably won't be because of that treatment.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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