Betaine HCl
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
Betaine HCl
Hey guys,
After some experimenting with anti histamines(allagra and Zantac). I have not seen much improvement in digestion or symptoms. Can this take awhile? All I notice is extreme thirst on top of everything else. However, I did try Betaine HCl with a protein heavy meal( 1 pill). Did not have any discomfort and the burning in my throat went away. Gonna up it to two pills and so forth until discomfort appears. I think Gabes mentioned supplementing with this. Has anyone else had any luck and how did you do? The relentless fatigue and dizziness is I'm guessing from malabsorption due to low stomach acid, low SIgA, Zinc? All intertwined of course. I go to bed most nights wondering if I'll wake up. I hope I'm on to something here. Still taking my med with lactose in it because insurance blahblahblah. I also need to check for H. Pylori as well. Is endoscopy the only way to test this accurately?
After some experimenting with anti histamines(allagra and Zantac). I have not seen much improvement in digestion or symptoms. Can this take awhile? All I notice is extreme thirst on top of everything else. However, I did try Betaine HCl with a protein heavy meal( 1 pill). Did not have any discomfort and the burning in my throat went away. Gonna up it to two pills and so forth until discomfort appears. I think Gabes mentioned supplementing with this. Has anyone else had any luck and how did you do? The relentless fatigue and dizziness is I'm guessing from malabsorption due to low stomach acid, low SIgA, Zinc? All intertwined of course. I go to bed most nights wondering if I'll wake up. I hope I'm on to something here. Still taking my med with lactose in it because insurance blahblahblah. I also need to check for H. Pylori as well. Is endoscopy the only way to test this accurately?
Vanessa
- Gabes-Apg
- Emperor Penguin
- Posts: 8332
- Joined: Mon Dec 21, 2009 3:12 pm
- Location: Hunter Valley NSW Australia
Vanessa,
Firstly, you can edit posts...(edit button top right of the post...)
Ok.... I wish I had a black or white answer to your question..... Like a lot of things in MC world the answer is 'it depends'
What I have learnt since doing all the reading/research on methylation is that each person reacts to animal protein differently.
For some, yes, Betaine will help.
For others it won't -
I purchased some Betaine, and just as I was going to start taking it, then got my dna/methylation results and it highlighted that Betaine was not necessarily the answer for me.
My suggestion is, if anti histamines have not helped, try the Betaine with animal protein meals, and see how things go. Give it a couple of weeks.
If no improvement, and you have the $90, do the dna testing, get methylation reports from the web and use that info to adjust eating/supplement plan to optimise wellness...
Yep, it is tiring and overwhelming that there are no easy answers... I can assure you that as time goes on, the trial and error process does reduce, and once you know what works for you, life in MC world does get easier, less complicated...
Firstly, you can edit posts...(edit button top right of the post...)
Ok.... I wish I had a black or white answer to your question..... Like a lot of things in MC world the answer is 'it depends'
What I have learnt since doing all the reading/research on methylation is that each person reacts to animal protein differently.
For some, yes, Betaine will help.
For others it won't -
I purchased some Betaine, and just as I was going to start taking it, then got my dna/methylation results and it highlighted that Betaine was not necessarily the answer for me.
My suggestion is, if anti histamines have not helped, try the Betaine with animal protein meals, and see how things go. Give it a couple of weeks.
If no improvement, and you have the $90, do the dna testing, get methylation reports from the web and use that info to adjust eating/supplement plan to optimise wellness...
Yep, it is tiring and overwhelming that there are no easy answers... I can assure you that as time goes on, the trial and error process does reduce, and once you know what works for you, life in MC world does get easier, less complicated...
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
Vanessa,
We have several members who have seen improvement in their digestion/symptoms by taking Betaine HCL. Hopefully some of them will see your post and respond.
If antihistamines are going to help, usually you will see benefits almost immediately, IOW in a day or less.
There are at least 4 tests available for testing for H. pylori:
1. Blood antibody test.
2. Urea breath test.
3. Stool antigen test.
4. Stomach biopsy.
Obviously the stomach biopsy is the most invasive, and probably the most reliable, but you might ask your doctor for an opinion on the other options.
Tex
We have several members who have seen improvement in their digestion/symptoms by taking Betaine HCL. Hopefully some of them will see your post and respond.
If antihistamines are going to help, usually you will see benefits almost immediately, IOW in a day or less.
There are at least 4 tests available for testing for H. pylori:
1. Blood antibody test.
2. Urea breath test.
3. Stool antigen test.
4. Stomach biopsy.
Obviously the stomach biopsy is the most invasive, and probably the most reliable, but you might ask your doctor for an opinion on the other options.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Thank you so much guys! I'm am lost in a sea of trial and error. I have to admit that the methylation is really hard for me to grasp....can you take an anti histamine and Betaine?
All I can do is keep plugging away. And of course I didn't see all of the new posts on methylation until after I posted my questions. I am also sorry if I am frustrating anyone with my questions.....it's hard to think when you feel so poorly which you guys totally get. I have no words for the amount of gratitude I have for this forum and the people who belong to it.
All I can do is keep plugging away. And of course I didn't see all of the new posts on methylation until after I posted my questions. I am also sorry if I am frustrating anyone with my questions.....it's hard to think when you feel so poorly which you guys totally get. I have no words for the amount of gratitude I have for this forum and the people who belong to it.
Vanessa
As far as I'm aware there's no reason why one cannot take an antihistamine while using Betaine HCL. Betaine is said to have antihistamine effects, but I'm not sure how significant they are.
Please don't feel like the Lone Ranger. Methylation issues can be very complex. Anyone who claims to completely understand methylation issues almost surely significantly overestimates their abilities.
Tex
Please don't feel like the Lone Ranger. Methylation issues can be very complex. Anyone who claims to completely understand methylation issues almost surely significantly overestimates their abilities.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
- Gabes-Apg
- Emperor Penguin
- Posts: 8332
- Joined: Mon Dec 21, 2009 3:12 pm
- Location: Hunter Valley NSW Australia
Methylation is a fairly complex, technical thing. And there are many variables....
And I don't claim to be an expert, but I have been learning and am aware based the experience of people here, those that have struggled to get wellness, the methylation info has provided some info as to why.
Depending on what issues the individual has, there is no quick fix .... It takes time with the right diet/supplements to fix issues. I expect my wellness journey will take me 2-3 years.
Donna - pulling up the info and my notes to answer your question....
Will reply soon
And I don't claim to be an expert, but I have been learning and am aware based the experience of people here, those that have struggled to get wellness, the methylation info has provided some info as to why.
Depending on what issues the individual has, there is no quick fix .... It takes time with the right diet/supplements to fix issues. I expect my wellness journey will take me 2-3 years.
Donna - pulling up the info and my notes to answer your question....
Will reply soon
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
- Gabes-Apg
- Emperor Penguin
- Posts: 8332
- Joined: Mon Dec 21, 2009 3:12 pm
- Location: Hunter Valley NSW Australia
Donna
Betaine HCL and methylation cycle
(grab a cuppa and read with a clear head!!)
some of my notes I have not put the website where i found the info ( when I first got my results I read about 20 or more websites interpreting my results... and some of this info is from my note book as I read through various websites)
effectiveness of Betaine HCL has to do with the status of your BHMT (02 04 08) and CBS SNPS
BHMT is Betaine-Homocysteine Methyltransferase
(I am trying to think of a layperson description for this, but it depends on your status for MTR/MTRR and CBS and the combo of all three as to what issues are occurring...)
CBS - layperson description explains pro's and cons of how you process animal protein
In my case - I dont have low stomach acid, i have methylation issues. trying to boost acid via betaine HCL wont resolve the issues. (which is why it does not work for all people)
general stuff from my notes: (sources provided where I have them)
- HCL should only be taken when inflammatory markers are normal and diarrhea is no longer a problem.
- HCL is needed by some to build up low stomach acid - those with multiple issues seem to need a lot of it
- Betaine can be a bit of a detoxer, so may cause D issues, which for a MC'er may seem like it is not working, when hence it is working it is detoxing!! I have read in quite a few sites that it is important to reduce toxins/metals first to boost cell health before doing high doses of any methyl donors (like active B12 etc)
I would recommend Molybdenum, Vit E, Magnesium, Vit C, Zinc to do this. It took me 6 months of high doses of these clearing toxins before I tolerated active form of B12.
- Betaine is a metabolite of choline, and is also known as trimethylglycine or TMG. Betaine hcl works by donating methyl (CH3) groups. This nutrient has the ability to convert homocysteine to methionine. Betaine hydrochloride means it is in combination with hydrochloric acid. Intake from foods is estimated at 0.5 to 2 grams a day. A methyl donor is simply any substance that can transfer a methyl group, a carbon atom attached to three hydrogen atoms, to another substance. Many important biochemical processes rely on methylation, including the metabolism of lipids, neurotransmitters, and DNA
REF: http://www.raysahelian.com/betaine.html
(in my case for my combo of SNP's having too many methyl donors causes MORE Issues than benefit. I had to clear away some of the toxins/metals, and get other nutrients in balance before I took anything in high doses that is classed as a Methyl Donor
(further layperson description - by converting homocysteine to methionine you are lowering histamine levels/intense histamine reactions... in my case for the myriad of things I have, I am taking methionine as a supplement to get balance (sort of short cut) and have noticeable improvement by doing this.
For those with low stomach acid then yes Betaine HCL is a good option to assist digestion.
If people are having ongoing issues (antihistamines and/or betaine is not working) why I suggest doing the testing and running the methylation reports.
If you are having issues digestion animal protein - it may not be because of low acid (or high acid). For some with certain mutations and combo of mutations, animal protein causes excess ammonia (which depletes BH4 which is linked to mast cell issues) and sulfite and sulfate (which stimulate excess cortisol) which causes excitotixicity, and hydrogen sulfide (linked to brain fog), all of this causes excess free radicals (causing cell damage increased inflammation) (mmmm over reactive stress reactions and issues with digestion, sounds like MC hey...)
If this is the case then betaine or TMG wont help
What will help.....
- limit intake of animal protein or take required items to balance the ammonia/sulfur
- you have to minimise sulfur intake (sulfur rich veges , sulfur supplements, sulfur drugs) this include NAC, avoid wine etc (and interestingly Magnesium is high in sulfur...) there is a list on the heartfixer website
- Molybdenum, Vit E will help reduce sulfur
- balance the excitoxicity with GABA
- reduce ammonia via supplementation - either Charcoal or Yucca or Carnitine
long story short - fixing the items mentioned above, will help with homocysteine balance and BH4 balance which will minimise histamine issues.
in my case, after 9 months of high doses of Molybdenum, Vit E etc, I notice I hardly ever need to take any anti-histamines (even if I have a high histamine meal!) I can be out in the paddock for hours where there is various grass and dust post mowing and not have any issues.
3 months ago I was using small doses of anti-histamine in those circumstances.
There is way more information about this at the heartfixer website - I have read the info there quite a few times and read articles by many others writing about Methylation (tim Jackson, Amy Yasko, Weston A Price, Nancy Mullen, etc ) there are so many complexities and each of them mention different points approaches. There is no simple black and white explanation for this and how to get it right. What I do know is there are three main things that apply to Methylation;
1. listen to your body.
2. and the tough one in MC world, D (or increase amount of BM's) is not always a bad thing. if you are detoxing you will have increased BM's and gut symptoms. Albeit you can not improve until the toxins are removed, so starting a supplement and then having D doesnt necessarily mean it is not working...
3. read and research and investigate options (and do more reading!). There are multiple way to fix acid issues. Problems digesting animal protein is not just about acid levels. Read blogs, ask questions. Like point 2 above, be prepared and know what may or may not happen when you start a certain supplement.
Like the MC healing process, it is a process, you cant rush steps or skip them.
The other thing discussed in Methylation treatments etc is that TMG (trimethylglicine) might be a better option instead of Betaine HCL.
(that is a whole other discussion on its own!!)
Again, considering TMG depends on the combo of your results in the methylation report namely your COMT/VDR status.
this is another area where my individual results gave the indicator that TMG was not a good idea for me
hope this answers your question (and helps more than it causes confusion)
Betaine HCL and methylation cycle
(grab a cuppa and read with a clear head!!)
some of my notes I have not put the website where i found the info ( when I first got my results I read about 20 or more websites interpreting my results... and some of this info is from my note book as I read through various websites)
effectiveness of Betaine HCL has to do with the status of your BHMT (02 04 08) and CBS SNPS
BHMT is Betaine-Homocysteine Methyltransferase
(I am trying to think of a layperson description for this, but it depends on your status for MTR/MTRR and CBS and the combo of all three as to what issues are occurring...)
CBS - layperson description explains pro's and cons of how you process animal protein
In my case - I dont have low stomach acid, i have methylation issues. trying to boost acid via betaine HCL wont resolve the issues. (which is why it does not work for all people)
general stuff from my notes: (sources provided where I have them)
- HCL should only be taken when inflammatory markers are normal and diarrhea is no longer a problem.
- HCL is needed by some to build up low stomach acid - those with multiple issues seem to need a lot of it
- Betaine can be a bit of a detoxer, so may cause D issues, which for a MC'er may seem like it is not working, when hence it is working it is detoxing!! I have read in quite a few sites that it is important to reduce toxins/metals first to boost cell health before doing high doses of any methyl donors (like active B12 etc)
I would recommend Molybdenum, Vit E, Magnesium, Vit C, Zinc to do this. It took me 6 months of high doses of these clearing toxins before I tolerated active form of B12.
- Betaine is a metabolite of choline, and is also known as trimethylglycine or TMG. Betaine hcl works by donating methyl (CH3) groups. This nutrient has the ability to convert homocysteine to methionine. Betaine hydrochloride means it is in combination with hydrochloric acid. Intake from foods is estimated at 0.5 to 2 grams a day. A methyl donor is simply any substance that can transfer a methyl group, a carbon atom attached to three hydrogen atoms, to another substance. Many important biochemical processes rely on methylation, including the metabolism of lipids, neurotransmitters, and DNA
REF: http://www.raysahelian.com/betaine.html
(in my case for my combo of SNP's having too many methyl donors causes MORE Issues than benefit. I had to clear away some of the toxins/metals, and get other nutrients in balance before I took anything in high doses that is classed as a Methyl Donor
(further layperson description - by converting homocysteine to methionine you are lowering histamine levels/intense histamine reactions... in my case for the myriad of things I have, I am taking methionine as a supplement to get balance (sort of short cut) and have noticeable improvement by doing this.
For those with low stomach acid then yes Betaine HCL is a good option to assist digestion.
If people are having ongoing issues (antihistamines and/or betaine is not working) why I suggest doing the testing and running the methylation reports.
If you are having issues digestion animal protein - it may not be because of low acid (or high acid). For some with certain mutations and combo of mutations, animal protein causes excess ammonia (which depletes BH4 which is linked to mast cell issues) and sulfite and sulfate (which stimulate excess cortisol) which causes excitotixicity, and hydrogen sulfide (linked to brain fog), all of this causes excess free radicals (causing cell damage increased inflammation) (mmmm over reactive stress reactions and issues with digestion, sounds like MC hey...)
If this is the case then betaine or TMG wont help
What will help.....
- limit intake of animal protein or take required items to balance the ammonia/sulfur
- you have to minimise sulfur intake (sulfur rich veges , sulfur supplements, sulfur drugs) this include NAC, avoid wine etc (and interestingly Magnesium is high in sulfur...) there is a list on the heartfixer website
- Molybdenum, Vit E will help reduce sulfur
- balance the excitoxicity with GABA
- reduce ammonia via supplementation - either Charcoal or Yucca or Carnitine
long story short - fixing the items mentioned above, will help with homocysteine balance and BH4 balance which will minimise histamine issues.
in my case, after 9 months of high doses of Molybdenum, Vit E etc, I notice I hardly ever need to take any anti-histamines (even if I have a high histamine meal!) I can be out in the paddock for hours where there is various grass and dust post mowing and not have any issues.
3 months ago I was using small doses of anti-histamine in those circumstances.
There is way more information about this at the heartfixer website - I have read the info there quite a few times and read articles by many others writing about Methylation (tim Jackson, Amy Yasko, Weston A Price, Nancy Mullen, etc ) there are so many complexities and each of them mention different points approaches. There is no simple black and white explanation for this and how to get it right. What I do know is there are three main things that apply to Methylation;
1. listen to your body.
2. and the tough one in MC world, D (or increase amount of BM's) is not always a bad thing. if you are detoxing you will have increased BM's and gut symptoms. Albeit you can not improve until the toxins are removed, so starting a supplement and then having D doesnt necessarily mean it is not working...
3. read and research and investigate options (and do more reading!). There are multiple way to fix acid issues. Problems digesting animal protein is not just about acid levels. Read blogs, ask questions. Like point 2 above, be prepared and know what may or may not happen when you start a certain supplement.
Like the MC healing process, it is a process, you cant rush steps or skip them.
The other thing discussed in Methylation treatments etc is that TMG (trimethylglicine) might be a better option instead of Betaine HCL.
(that is a whole other discussion on its own!!)
Again, considering TMG depends on the combo of your results in the methylation report namely your COMT/VDR status.
this is another area where my individual results gave the indicator that TMG was not a good idea for me
http://www.heartfixer.com/AMRI-Nutrigenomics.htm#BHMT: Betaine-Homocysteine MethyltransferaseBHMT (Betaine Homocysteine Methyl Transferase) directly methylates homocysteine back in to methionine, serving as a “back door” pathway to “pull” homocysteine away from the CBS “sulfate drain”. Thus if you bear CBS or BHMT abnormalities, it makes sense to support BHMT function. DMG (dimethylglycine) and TMG (trimethylglycine) stimulate BHMT, and can be utilized if you are not overly sensitive to methyl group supplementation (based upon you COMT/VDR status). Phosphatidylserine stimulates BHMT (and we also use it to moderate elevated cortisol levels), as does phosphatidylcholine (which we use to treat atherosclerosis). Phosphatidylcholine can be admixed with EDTA (detoxifies metals), creating a quite useful supplement.
hope this answers your question (and helps more than it causes confusion)
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
- Gabes-Apg
- Emperor Penguin
- Posts: 8332
- Joined: Mon Dec 21, 2009 3:12 pm
- Location: Hunter Valley NSW Australia
the tough part about the digestion system is that there are no easy affordable tests per say that will give us 'exact' information as to what is going on (or what is not going on) type thing...
especially when multiple things can cause the same symptom.... and a symptom can mean multiple things...
I am glad that it makes some sense,
Vanessa - What are your main symptoms? and are you keeping a food/activity/symptom diary?
ie can you tell if a meal with animal protein causes you more issues?
for years the Rice protein shakes that i use, have always settled easier/better. looking at my methylation results and some of what i discuss above reiterated to me why they settle better.
Also keep in mind, we cant avoid all triggers and do everything perfectly.. in my case, Magnesium might be classed as being high in sulphur, but I was deficient in Magnesium and my body needs it. with this information I know that i need to keep taking Molybdenum and Vit E to balance the extra sulphur that having the magnesium creates....
and once the deficiencies are corrected, cell health is optimised and methylation is ticketyboo, (running as it should), my reactions to these things will reduce
You might like to try the betaine HCL, expect that the D or frequent BM's may continue (as you are detoxing) but if the other symptoms reduce then there is a good chance it is working for you...
With any supplement type thing, start low dose, and work gradually up to full dose. if there is deficiency of nutrient/mineral it can take a minimum of 8 weeks of full dose to correct deficiency, so it may take 8 weeks before you can fully gauge if it is really working for you.
obviously when in this process if symptoms get worse or the D is really bad, stop. now is not the time for that particular supplement.
especially when multiple things can cause the same symptom.... and a symptom can mean multiple things...
I am glad that it makes some sense,
Vanessa - What are your main symptoms? and are you keeping a food/activity/symptom diary?
ie can you tell if a meal with animal protein causes you more issues?
for years the Rice protein shakes that i use, have always settled easier/better. looking at my methylation results and some of what i discuss above reiterated to me why they settle better.
Also keep in mind, we cant avoid all triggers and do everything perfectly.. in my case, Magnesium might be classed as being high in sulphur, but I was deficient in Magnesium and my body needs it. with this information I know that i need to keep taking Molybdenum and Vit E to balance the extra sulphur that having the magnesium creates....
and once the deficiencies are corrected, cell health is optimised and methylation is ticketyboo, (running as it should), my reactions to these things will reduce
You might like to try the betaine HCL, expect that the D or frequent BM's may continue (as you are detoxing) but if the other symptoms reduce then there is a good chance it is working for you...
With any supplement type thing, start low dose, and work gradually up to full dose. if there is deficiency of nutrient/mineral it can take a minimum of 8 weeks of full dose to correct deficiency, so it may take 8 weeks before you can fully gauge if it is really working for you.
obviously when in this process if symptoms get worse or the D is really bad, stop. now is not the time for that particular supplement.
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
I have been keeping a journal and the only thing that stands out is every two weeks during hormonal times, my digestion has a real bad day. The stomach burning at night comes and goes and I'm sure it is the lactose in the pill I take at night which I'm in the process of getting compounded. Its not something I can just go off of without withdrawal. Its been 3 days on 2400 mg of the Betaine and have noticed feeling better, but we'll see. I just could be on my "good" week. I need to study a lot more but the heartfixer website is a good one. My accupuncturists seems to be well versed so I will show her my methylation report. Where I get stuck is the +/- situations. I am +/+ for VDR Taq and CBS A360A.
I am +/- for COMT V158M, COMT H62H, and MTRR A66G.
Can you pay this website to interpret your results for you? I looked but couldn't see a spot to do so.
It seems if one is present the other one cancels it out. I may have the sulpher issue as well. My mother is allergic to sulpha medications Thank you sooo much for your insight. I know that just decoding your own health is a full time job. Do you see a naturopath or are you doing this all on your lonesome? I was also not aware of the detox Betaine HCl could have so I will go slower. Not knowing that could have really messed me up. Great job on your progress! Cheers!
I am +/- for COMT V158M, COMT H62H, and MTRR A66G.
Can you pay this website to interpret your results for you? I looked but couldn't see a spot to do so.
It seems if one is present the other one cancels it out. I may have the sulpher issue as well. My mother is allergic to sulpha medications Thank you sooo much for your insight. I know that just decoding your own health is a full time job. Do you see a naturopath or are you doing this all on your lonesome? I was also not aware of the detox Betaine HCl could have so I will go slower. Not knowing that could have really messed me up. Great job on your progress! Cheers!
Vanessa
- Gabes-Apg
- Emperor Penguin
- Posts: 8332
- Joined: Mon Dec 21, 2009 3:12 pm
- Location: Hunter Valley NSW Australia
Interpreting the methylation reports etc, I have been doing it myself via various websites.
On the Livewello web site, there is a different methylation report, and they have a listing of practitioners that can interpret reports and provide guidance on supplement regime. Quite a few of them offer Skype sessions, so they don't have to be local. They are 'reasonable' cost wise when compared to other practitioners. $100-$300 for 1.5hr session and some are subsidised by insurance.
I did see one website of a group in the USA, and they charged $1200 to do interpretation and provide ongoing supplement advice.
Had I not seen improvement, then I would have considered doing one or two sessions with one of the practitioners from the livewello site.
The hiccup to consulting with a practitioner is the MC factor.... The eating plan we follow and how our body reacts is very unique. Some of their recommendations would not work for a MC'er. So I would still research and review any recommendation before starting...
Mmmm hormone reactions affecting digestion, another reason to fix methylation issues. Clearing toxins/metals helps to settle hormone issues
If it was me, with the combo of snp's you have, the hormone issues, I would start molybdenum and Vit E first.... This will help balance sulfur, help to clear toxins, gently...
This will start to help and won't trigger methyl donors... I would start them one at a time, work up to full dose over a couple of weeks. and take them at full dose for 8 weeks before you start anything else.
(Moly 150mcg is good start - 250mcg would be better, I take 300mcg per day).
(Vit E 800iu is good start - I take 1200iu per day)
As you are clearing toxins, there maybe an increase in BM. If the increase of BM is too much reduce the dose a bit...
Also with the VDR Taq, snp are you taking D3 daily.
On the Livewello web site, there is a different methylation report, and they have a listing of practitioners that can interpret reports and provide guidance on supplement regime. Quite a few of them offer Skype sessions, so they don't have to be local. They are 'reasonable' cost wise when compared to other practitioners. $100-$300 for 1.5hr session and some are subsidised by insurance.
I did see one website of a group in the USA, and they charged $1200 to do interpretation and provide ongoing supplement advice.
Had I not seen improvement, then I would have considered doing one or two sessions with one of the practitioners from the livewello site.
The hiccup to consulting with a practitioner is the MC factor.... The eating plan we follow and how our body reacts is very unique. Some of their recommendations would not work for a MC'er. So I would still research and review any recommendation before starting...
Mmmm hormone reactions affecting digestion, another reason to fix methylation issues. Clearing toxins/metals helps to settle hormone issues
If it was me, with the combo of snp's you have, the hormone issues, I would start molybdenum and Vit E first.... This will help balance sulfur, help to clear toxins, gently...
This will start to help and won't trigger methyl donors... I would start them one at a time, work up to full dose over a couple of weeks. and take them at full dose for 8 weeks before you start anything else.
(Moly 150mcg is good start - 250mcg would be better, I take 300mcg per day).
(Vit E 800iu is good start - I take 1200iu per day)
As you are clearing toxins, there maybe an increase in BM. If the increase of BM is too much reduce the dose a bit...
Also with the VDR Taq, snp are you taking D3 daily.
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
I hope this is not a dumb question. I have been reading so much and trying to understand and comprehend all the facts of this disease. What are the symptoms of methylation issues? I think I gathered from all of the above messages that low stomach acid is one so I'm guessing heartburn? Are there other symptoms? How would you know?
Jari
Diagnosed with Collagenous Colitis, June 29th, 2015
Gluten free, Dairy free, and Soy free since July 3rd, 2015
Diagnosed with Collagenous Colitis, June 29th, 2015
Gluten free, Dairy free, and Soy free since July 3rd, 2015
Hi Jari,
That's actually a very good question, though it's not necessarily easy to answer, because methylation is a rather complex, and poorly understood phenomenon, and research has only barely scratched the surface of this topic. Here are some of my reflections on the issue:
Why I Believe Methylation Issues Are Associated With MC
How Methylation Issues Have Affected Me
And Gabes has some informative posts in that category also:
Attn those with MTHFR - Pyrrole - Methylation issues
Medications that affect methylation
interpreting Methylation Report
and of course there are others at: Methylation Issues
I hope that some of this is helpful,
Tex
That's actually a very good question, though it's not necessarily easy to answer, because methylation is a rather complex, and poorly understood phenomenon, and research has only barely scratched the surface of this topic. Here are some of my reflections on the issue:
Why I Believe Methylation Issues Are Associated With MC
How Methylation Issues Have Affected Me
And Gabes has some informative posts in that category also:
Attn those with MTHFR - Pyrrole - Methylation issues
Medications that affect methylation
interpreting Methylation Report
and of course there are others at: Methylation Issues
I hope that some of this is helpful,
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.