Originally thought IBS ,stool test suggests IBD please help

[jlbattin]

I had the side pains until I cut out gluten, dairy, soy, and eggs, and eventually they went away. They only creep back now when I eat something I shouldn't (either by accident or because I'm trying a new food). The bloating and pains were surreal until I made the diet changes.

Speaking of gluten, here's an interesting article on why you should avoid gluten with all autoimmune diseases: http://eatlocalgrown.com/article/15097- ... html?c=JER

[kenvh]

My Calprotectin is 412 which as I understand it is very high.

I think this calprotectin level is low for Crohns and UC, but a bit on the high side for MC. I had half your level at the time of diagnosis for Collagenous colitis, and often the calprotectin isn't raised at all. I think you need a colonoscopy to get tonthe bottom of this. Be sure to tell the gastroenterologist to take at least 6 biopsies of the colon in order to rule MC in or out.

But you're right, calprotectin levels above 50 are strongly indicative of IBD, not IBS.

-- Tor

often the calprotectin isn't raised at all??
Is this true?
why isnt the calprotectin not always positive in MC?
I feel i have some inflammation.
My first test was 107. my second was <15. so he said.. U have PI-IBS.
Im still in a mind struggle and i really dont know if i have post infectious IBS or MC.
I just had 2 biopsies that are negative. But2 biopsies isnt a lot.
I wont do another colonscopy either.
So if the calprotectin isnt always positive, how the hell can i know??
Why wouldnt the calprotectin be positive in MC?

greets ken

[Tor]

Danish researchers have investigated calprotectin levels in CC, and found that they aren't always raised: http://journals.lww.com/eurojgh/Abstrac ... _in.9.aspx.

A very thorough European consensus article cites the article above and states that calprotectin levels are contradictory in MC: http://www.ncbi.nlm.nih.gov/pubmed/22704658.

I don't know the reason for this, but my guess is that the inflammation levels in MC can wax and wane.

On the other hand, other researchers have shown that calprotectin levels over 50 usually are pathological, and not "IBS". There are a lot off sources for this.

The only test diagnostic for MC is biopsies with a thickened collagen band and/or increased lymphocyte count. The collagen band and inflammation in MC are usually patchy, and at least 6 biopsies is recommended. The free consensus article cited above is a good source for this information.

--Tor

[Jimbo1968]

I guess like any test it will produce false positives and false negatives