Off topic - Lynch syndrome

Tor · Post by **Tor** » Sun Nov 08, 2015 5:00 pm

On my mothers side of the family 3 generations have had a lot of colorectal cancer incidents. There are also a lot of adenomas - both with and without high-grade dysplacia.

Analyzing my 23andMe results in Promethease and Livewello, I see the following risk genes:
rs1800734(A;A)
rs1800937(C;T)
rs1800935(C;T)
rs17420802(A;G)

All of these seem to be linked to Lynchs syndrome. Does anybody know if this is sufficient to qualify for Lynch syndrome? Tex?

Sorry for being off topic, but I know there are some knowledgeable people here. Thanks!

-- Tor

Post by **tex** » Sun Nov 08, 2015 5:12 pm

Tor,

I'm sorry, but I have no knowledge about Lynch syndrome nor the genetic predispositions associated with it.

Anything that has anything to do with health, or living with medical issues is right on topic on this particular message board, so please feel free to post anything you want.

Tex

Sheila · Post by **Sheila** » Mon Nov 09, 2015 2:35 pm

Wow, Lynch syndrome. Very good friends who are originally from Long Island, NY are part of the Lynch syndrome study. My dear friend, Kerry Lynch, died after having both colorectal cancer and pancreatic cancer. His entire family seems to have been dealt this terrible fate. His three children are to date, unaffected.

If you're interested, I can contact Kerry's wife and ask about the study.

Sheila W

Tor · Post by **Tor** » Mon Nov 09, 2015 2:47 pm

Sheila wrote:If you're interested, I can contact Kerry's wife and ask about the study.
Sheila W

Thanks, Sheila, but I don't think that's necessary. The question is probably too detailed. I'll bring this up on my next appointment with the GI specialist.

-- Tor

Sheila · Post by **Sheila** » Mon Nov 09, 2015 3:55 pm

I didn't find out much, Tor. The syndrome is named for Dr. Henry Lynch, a doctor at the Univ. of Nebraska. People are missing specific cancer-fighting genes. Men seem to get colorectal cancer and women get ovarian cancer.

Good luck,
Sheila W