I've just noticed that my mother takes sulfasalazine, which from what I understand is an anti inflammatory for her colitis. I've noticed that Entocort has been much spoken about on this website. Is it still an anti inflammatory or does it work in a different way.
It's strange just having something sitting there that could offer me some relief and yet not being able to touch it.
As a final question is the water in watery diarrhea acidic, I'm trying to account for why my rectum is so tender and my haemorrhoids so easily aggravated since all this diarrhea.
Sulfasalazine is it as effective as Entocort
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Gabes-Apg
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thats ok - that is why i mentioned it
i think this post would answer most of your questions
http://www.perskyfarms.com/phpBB2/viewt ... fasalazine
i think this post would answer most of your questions
http://www.perskyfarms.com/phpBB2/viewt ... fasalazine
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
Jim,
Here is some basic information on sulfasalazine:
Sulfasalazine is a prodrug, that is to say, it does not become active in the digestive system until it is broken down by bacteria in the colon, into 5-aminosalicylic acid, (5-ASA), and sulfapyridine. While sulfapyradine has a therapeutic effect for rheumatoid arthritis, no beneficial effect from sulfapyradine has been observed for treating inflammatory bowel disease. Since many people tend to react adversely to sulfa drugs, sulfasalazine has mostly been replaced with mesalamine, (sometimes referred to as mesalazine, to further confuse the matter), in the treatment of IBDs.
Mesalamine contains the active moiety of sulfasalazine, known as 5-aminosalicyclic acid, while eliminating the sylfapyradine. Mesalamine is a derivative of salicylic acid, which means that it is related to NSAIDs. For many people who have an inflammatory bowel disease, NSAIDs have been shown to stimulate leukotriene production, which can cause inflammation and D. Therefore, virtually anyone subject to an IBD flare because of NSAIDs, will also react adversely to mesalamine and/or sulfasalazine.
Unless you have rheumatoid arthritis, mesalamine is a much safer drug to use, with regard to side effect risks, because many people with MC cannot tolerate sulfa drugs. However, sulfasalazine has been around for a long time, and is cheap to manufacture, so it's priced much lower than mesalamine.
IMO, (and this is strictly my unprofessional opinion), Entocort is far more effective, and generally safer, (especially after the dosage is tapered down to a low maintenance dose), than either sulfasalazine or mesalamine. Mesalamine is known to cause pancreatitis in a few cases, especially with long-term use, and the pancreas is not a good organ to inflame, because of it's vital digestive system functions.
I hope that some of that is helpful.
Tex
Here is some basic information on sulfasalazine:
Sulfasalazine is a prodrug, that is to say, it does not become active in the digestive system until it is broken down by bacteria in the colon, into 5-aminosalicylic acid, (5-ASA), and sulfapyridine. While sulfapyradine has a therapeutic effect for rheumatoid arthritis, no beneficial effect from sulfapyradine has been observed for treating inflammatory bowel disease. Since many people tend to react adversely to sulfa drugs, sulfasalazine has mostly been replaced with mesalamine, (sometimes referred to as mesalazine, to further confuse the matter), in the treatment of IBDs.
Mesalamine contains the active moiety of sulfasalazine, known as 5-aminosalicyclic acid, while eliminating the sylfapyradine. Mesalamine is a derivative of salicylic acid, which means that it is related to NSAIDs. For many people who have an inflammatory bowel disease, NSAIDs have been shown to stimulate leukotriene production, which can cause inflammation and D. Therefore, virtually anyone subject to an IBD flare because of NSAIDs, will also react adversely to mesalamine and/or sulfasalazine.
Unless you have rheumatoid arthritis, mesalamine is a much safer drug to use, with regard to side effect risks, because many people with MC cannot tolerate sulfa drugs. However, sulfasalazine has been around for a long time, and is cheap to manufacture, so it's priced much lower than mesalamine.
IMO, (and this is strictly my unprofessional opinion), Entocort is far more effective, and generally safer, (especially after the dosage is tapered down to a low maintenance dose), than either sulfasalazine or mesalamine. Mesalamine is known to cause pancreatitis in a few cases, especially with long-term use, and the pancreas is not a good organ to inflame, because of it's vital digestive system functions.
I hope that some of that is helpful.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.