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In a statement Monday, Abigail Bozarth, a spokeswoman for AstraZeneca, which makes Nexium, said the company believes all its proton pump inhibitors "are generally safe and effective when used in accordance with the label. This has been established through human data studies and more than a decade of real world clinical use." It said AstraZeneca was not consulted during the research and could not comment further.
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
In a statement Monday, Abigail Bozarth, a spokeswoman for AstraZeneca, which makes Nexium, said the company believes all its proton pump inhibitors "are generally safe and effective when used in accordance with the label.
AstraZeneca wisely labeled their product for a maximum of 2-weeks of use. But hardly anyone stops after 2 weeks, because 2 weeks is sufficient for the body to build up a dependence based on the fact that when the drugs are discontinued, there's a rebound effect that's worse than the original symptoms. Consequently, doctors unwisely continue to prescribe the drugs for long-term use (which amounts to off-label use of course).
The list of adverse side effects for PPIs is beginning to become rather long.
Thanks for the link.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
You're closer than I was. Either I had it confused with another product, or they've changed the label. The current label shows that it can be used for up to 8 weeks, and re-prescribed for another 8 weeks if needed:
And you're right of course that not only AstraZeneca but all pharmaceutical companies encourage long-term use of virtually all of their products. They don't make much from a short treatment regimen, but they get rich by hooking patients for life.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Of course! I just don't like how they wash their hands of any evidence against their products. Basically implying that long term with side effects are misusing the product.
If only they used it according to our recommendation that we basically encourage doctors to ignore.
I know this is how the system works, it just bothers me.
Remember when most of the otc proton pump inhibitors were mostly by prescription only? If you had a malady of some sort (perhaps a bit facetious) the ordering physician claimed you need nexium or whatever. Some physicians will tell you that an elevated cholesteral number made you a recruit for a lipid reducer pill too! After an alotted amount of time the generics are allowed to come out and further entice physicians and patients alike; by that time, the drug manufacturers have come out with a more powerful better formulated version of what you now can by at your local drugstore or Walmart.
I just came from a pcp visit as I need a colonoscopy and he says: "well, your cholesterol is a bit high." Ok it's 220 but I am trying and without eating my dairy I truly am trying to stay on the healthy side. It's almost like you are frightened to mention you pass gas, belch or that your hiatal hernia bugs you sometimes not to mention my aching lower back. This is what keeps our doctors in business and the pharmaceutical companies for crying out loud!
That's my two cents worth and it cost me another co-pay to hear this today and now I'm loading it onto all you PO'd people! Tomorrow will be better...
220 is not high for total cholesterol. That's propaganda from the pharmaceutical reps promoting statin sales.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
