Glutathione Deficiency

[Gabes-Apg]

My interpretation is that as some of the key amino acids are low ( glycine, glutamic acid and cysteine and Taurine) this is affecting the bodies ability to make glutathioine and leads to glutathionine deficiency.

with many people here having issues with 'low acid' and in Deb's post that she was deficient in Glutathioine - it was a hint at the root cause of the issues...
it reiterates the importance of amino acids and their linkage into the methylation cycle

taking this a step further..... this links provides a good explanation of the steps/process. Within it i found the quoted text below, it is another element to people having 'high B12' in blood tests but still feeling poorly...

http://phoenixrising.me/research-2/glut ... onynenburg

One of the jobs that glutathione normally does is to protect your supply of vitamin B12 from reacting with toxins. If left unprotected, vitamin B12 is very reactive chemically. If it reacts with toxins, it can’t be used for its important jobs in your body. A routine blood test for vitamin B12 will not reveal this problem. In fact, many people with CFS appear to have elevated levels of B12 in their blood, while their bodies are not able to use it properly. The best test to reveal this is a urine organic acids test that includes methylmalonic acid. It will be high if the B12 is being sidetracked, and this is commonly seen in people with CFS.

When your glutathione level goes too low, your B12 becomes naked and vulnerable, and is hijacked by toxins. Also, the levels of toxins rise in the body when there isn’t enough glutathione to take them out, so there are two unfortunate things that work together to sabotage your B12 when glutathione goes too low

[tex]

Lilia,

To add to what Gabes posted, remember that the goal of the digestion of food is to (ideally) break all food down to the individual amino acids. Amino acids are the building blocks used to create new tissue (both for healing and for growing). When digestion is compromised by chronic inflammation however, digestion is incomplete (because the small intestine is unable to produce adequate amounts of certain enzymes needed to complete the digestive process, and in some cases even the pancreatic enzyme output is compromised).

This can cause only partial digestion of many foods, resulting in short to moderate length chains of amino acids, rather than individual amino acids. These chains (which are sections taken out of molecules) are known as peptides, and it is these peptides that can leak into the bloodstream when leaky gut is active, and it is these peptides that cause the immune system to launch an autoimmune reaction against them (because peptides should never be in the bloodstream — only amino acids should be allowed to enter the bloodstream).

Anyway, the reason why we may be short on certain amino acids when MC is active is because of the incomplete digestion problem described above.

Tex