Has anyone tried diet only instead of Budesonide? I am trying to do it without the med and I have osteoporosis?
Don't know how much to take if I go on it? For how long and how much is systemic? I sure there is something in the archive but have a hard time searching. I will book mark it because Tex taught me that.
The osteoporosis thing scares me as much as a flare does. I had a flare today from the same things I eat over and over. I am avoiding the list of sensitivities from enterolab.
Budesonide and osteoporosis
Moderators: Rosie, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
Hi Janie,
The reason why there is an increased risk of osteoporosis with taking a corticosteroid is because corticosteroids deplete magnesium and magnesium is absolutely necessary (along with vitamin D) in order to allow the body to use the calcium in the blood to strengthen bones. The risk can be avoided by taking an adequate magnesium supplement at all times.
The osteoporosis risk is rather slim with budesonide because only up to roughly 20 % of it is absorbed into the bloodstream. IOW, most of it stays in the gut, where it is needed.
The makers of Uceris insist that none of the budesonide in their product enters the bloodstream because it does not become activated until it has passed into the colon. Therefore, theoretically at least, it cannot contribute to osteoporosis.
Please be aware that according to published researched (this is referenced in my book, page 60), corticosteroid-naive patients (that is, patients who are taking a corticosteroid for the first time) have only a very minimal increased risk of osteoporosis as a result of the budesonide. However if the treatment is stopped and then started again, or if there is a prior history of taking a corticosteroid, then there is an increased risk of osteoporosis.
Maybe the reaction was caused by accidental cross-contamination or stress. Many of us here have never used budesonide, including me. We treat our MC by diet changes alone.
I hope that some of this is helpful.
Tex
The reason why there is an increased risk of osteoporosis with taking a corticosteroid is because corticosteroids deplete magnesium and magnesium is absolutely necessary (along with vitamin D) in order to allow the body to use the calcium in the blood to strengthen bones. The risk can be avoided by taking an adequate magnesium supplement at all times.
The osteoporosis risk is rather slim with budesonide because only up to roughly 20 % of it is absorbed into the bloodstream. IOW, most of it stays in the gut, where it is needed.
The makers of Uceris insist that none of the budesonide in their product enters the bloodstream because it does not become activated until it has passed into the colon. Therefore, theoretically at least, it cannot contribute to osteoporosis.
Please be aware that according to published researched (this is referenced in my book, page 60), corticosteroid-naive patients (that is, patients who are taking a corticosteroid for the first time) have only a very minimal increased risk of osteoporosis as a result of the budesonide. However if the treatment is stopped and then started again, or if there is a prior history of taking a corticosteroid, then there is an increased risk of osteoporosis.
Maybe the reaction was caused by accidental cross-contamination or stress. Many of us here have never used budesonide, including me. We treat our MC by diet changes alone.
I hope that some of this is helpful.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Budesonide and osteoporosis
Thanks Tex,
This disease is stressful. I take 800mg Magnesium glycinate and 8000u of Vit D. Also spray 100 mg mag. oil before bed.
I read your book and understand the restart of Budesonide can increase osteoporosis. Still don't understand how long to be on it and what dose and weaning down. All my GI Doc. says was 12 weeks. I pinned him down that it doesn't cure it though. He didn't say anything of weaning etc. I did call the office and asked for an order to stain for Mast cells on my slides.
Everyone on this site especially you and Gabes, are so helpful and reassuring to all us newbies.
This disease is stressful. I take 800mg Magnesium glycinate and 8000u of Vit D. Also spray 100 mg mag. oil before bed.
I read your book and understand the restart of Budesonide can increase osteoporosis. Still don't understand how long to be on it and what dose and weaning down. All my GI Doc. says was 12 weeks. I pinned him down that it doesn't cure it though. He didn't say anything of weaning etc. I did call the office and asked for an order to stain for Mast cells on my slides.
Everyone on this site especially you and Gabes, are so helpful and reassuring to all us newbies.
Janie
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Gabes-Apg
- Emperor Penguin
- Posts: 8330
- Joined: Mon Dec 21, 2009 3:12 pm
- Location: Hunter Valley NSW Australia
Janie
this disease is stressful at first... with time, when you have your safe eating plan figured out, and you have resolved magnesium deficiency, and some healing happens, then it is way less stressful.
it is early days for you in the journey, you are researching and asking questions which is great.
I never used budesonide. Diet is my main management tool.
Also there are other options other than budesonide. It is a bit of work in progress at the moment but there is a bit of a medication guide here
http://www.perskyfarms.com/phpBB2/viewtopic.php?t=22330
this disease is stressful at first... with time, when you have your safe eating plan figured out, and you have resolved magnesium deficiency, and some healing happens, then it is way less stressful.
it is early days for you in the journey, you are researching and asking questions which is great.
I never used budesonide. Diet is my main management tool.
Also there are other options other than budesonide. It is a bit of work in progress at the moment but there is a bit of a medication guide here
http://www.perskyfarms.com/phpBB2/viewtopic.php?t=22330
Gabes Ryan
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
Janie,
Here are my thoughts on tapering the dose of budesonide:
Ideally, dose reductions should not be made until stable remission has been the rule for a couple of weeks or so, or until constipation appears. Many members remain on a dose until they develop the signs of constipation and then they reduce the dose to the next level until they get down to 1 capsule (3 mg) per day. After reducing the dose to 1 capsule per day, some members here stay on that dose for 2 weeks, while others continue for up to 4 weeks. And they follow the same general pattern as they continue to lower the dose, to 1 capsule every other day, then 1 every third day, and some go to 1 every fourth day.
Others continue to taper to 5 or even 6 day intervals, especially if they have had problems withdrawing from budesonide successfully in the past. We all have different responses to medications and healing progress, so as Gabes says, we have to kind of listen to what our body is telling us, and modify our treatment program accordingly, as needed. In general, slower is better, but there's no way to be sure what is optimal in every case.
You're very welcome,
Tex
Here are my thoughts on tapering the dose of budesonide:
Ideally, dose reductions should not be made until stable remission has been the rule for a couple of weeks or so, or until constipation appears. Many members remain on a dose until they develop the signs of constipation and then they reduce the dose to the next level until they get down to 1 capsule (3 mg) per day. After reducing the dose to 1 capsule per day, some members here stay on that dose for 2 weeks, while others continue for up to 4 weeks. And they follow the same general pattern as they continue to lower the dose, to 1 capsule every other day, then 1 every third day, and some go to 1 every fourth day.
Others continue to taper to 5 or even 6 day intervals, especially if they have had problems withdrawing from budesonide successfully in the past. We all have different responses to medications and healing progress, so as Gabes says, we have to kind of listen to what our body is telling us, and modify our treatment program accordingly, as needed. In general, slower is better, but there's no way to be sure what is optimal in every case.
You're very welcome,
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
