According to Dr. Ritchie Shoemaker, a leading biotoxin researcher with a medical degree from Duke University, Chronic Inflammatory Response Syndrome (CIRS), is the result of chronic inflammation produced by exposure to biotoxins (toxins produced from living organisms) that come from mold (mycotoxins), tick-borne infections like Babesia, dinoflagellates, blue-green algae, some reef fish, and the brown recluse spider. The most common trigger of CIRS is usually the combination of mycotoxins, bacteria, VOCs, chemicals, and other damaging pathogens found within water damaged buildings [1].
.24% of the population is genetically susceptible to getting very sick from biotoxins. This can be determined by a very simple HLA-DR blood test. Dr. Shoemaker, leading expert in CIRS, explains that for these genetically susceptible individuals, biotoxins can’t be “tagged” by the body, and so the body then responds the only way it can: with fierce inflammation. But animals have also become very sick in water damaged buildings, so it’s not 100% necessarily, that the genetically susceptible that are at risk; though they are much more prone to developing chronic issues
http://thelowhistaminechef.com/the-mold-histamine-link/