Ok I think I need to better understand something in this dept.
It appears something affects Motility in one way or another....
Food sensitivties
Medicine
Environment
Physical body receptors acceptance or un-acceptance
I have now noticed that when I get stressed or have overstimulated my brain/body (and it doesn't matter how it gets that way - gardening, a great debated discussion, sex...) then it doesn't take long for the gut to respond and make me go to the bathroom numerous times.
BUT
I can take a sumatriptan Migraine Pill and the motility comes to a screeching halt. Once the med has potentially done its job and worked itself out of my system the gut appears to revert back to freaking out over other unknown (or known if testing fate) then 'things' I'll call them because I can't for the life of me figure out what they continue to be for me at this time. My Bristol continues to hover around 6 mostly and I'll be ooied if it attempts a 5 once in a while.
The Immune system must be working on the migraine pill invader and therefore is semi ignoring the fact that the gut isn't as important..correct?
I feel everytime the body has an unusual disturbance the gut gets a reprieve...how can we get to this reprieve status more often?
Perplexed
Erica
Motility 101
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
Motility 101
To Succeed you have to Believe in something with such a passion that it becomes a Reality - Anita Roddick
Dx LC April 2012 had symptoms since Aug 2007
Dx LC April 2012 had symptoms since Aug 2007
Erica,
Sumatriptan works by cerebral vasoconstriction. IOW it narrows blood vessels around the brain and this tends to preempt migraines by minimizing the possibility of spasms in those vessels.
Interestingly, that is pretty much exactly what caffeine does. And nicotine also constricts blood vessels. Presumably that may have something to do with the reason why smoking after sex was so popular before it became politically incorrect (smoking, not sex
).
But it's not easy to visualize coffee "preventing" a trip to the bathroom.
Of course coffee contains many other ingredients besides caffeine.
So have you by any chance ever noticed a similar effect from caffeine?
Tex
Sumatriptan works by cerebral vasoconstriction. IOW it narrows blood vessels around the brain and this tends to preempt migraines by minimizing the possibility of spasms in those vessels.
Interestingly, that is pretty much exactly what caffeine does. And nicotine also constricts blood vessels. Presumably that may have something to do with the reason why smoking after sex was so popular before it became politically incorrect (smoking, not sex
).But it's not easy to visualize coffee "preventing" a trip to the bathroom.
Of course coffee contains many other ingredients besides caffeine.So have you by any chance ever noticed a similar effect from caffeine?
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
HI Tex,
Potentially when I drink my Mtn Dew I 'never' have to run to the bathroom....I say this because usually I am eating food with it. But caffeine seems to be a part of migraine relief products along with the pain reliever part in them too.
I have been able to drink Mtn Dew alone with no problem....gads that sound so strange, because of the sugar but I don't drink gobs of it either. Maybe I should
but then I'm not looking for a caffeine high either.
I'm basically trying to figure this puzzle piece out about the med interfering with the motility...and I can't put my finger on it yet. I take a 100mg Sumatriptan and in 12 hours if it doesn't quite relieve me I take another one. So far this go around yesterday to today I have only had to take 200 mg total. Unfortunately in another day I can expect to have a bathroom running kind of day.
During this time my motility slows enough that my BM's are practically 5 and consistent but I sure do not like the high feeling I have while on this med...so would not care to take this med with this kind of side effect for a long term basis.
Potentially when I drink my Mtn Dew I 'never' have to run to the bathroom....I say this because usually I am eating food with it. But caffeine seems to be a part of migraine relief products along with the pain reliever part in them too.
I have been able to drink Mtn Dew alone with no problem....gads that sound so strange, because of the sugar but I don't drink gobs of it either. Maybe I should
but then I'm not looking for a caffeine high either.I'm basically trying to figure this puzzle piece out about the med interfering with the motility...and I can't put my finger on it yet. I take a 100mg Sumatriptan and in 12 hours if it doesn't quite relieve me I take another one. So far this go around yesterday to today I have only had to take 200 mg total. Unfortunately in another day I can expect to have a bathroom running kind of day.
During this time my motility slows enough that my BM's are practically 5 and consistent but I sure do not like the high feeling I have while on this med...so would not care to take this med with this kind of side effect for a long term basis.
To Succeed you have to Believe in something with such a passion that it becomes a Reality - Anita Roddick
Dx LC April 2012 had symptoms since Aug 2007
Dx LC April 2012 had symptoms since Aug 2007
This is strange Erica. I could understand it If the meds relaxed you, but this is quite the opposite....
I'm starting to think an anxiety med would benefit me. Too bad one doesn't exist without side effects. Sadly I can't be on "vacation" everyday.
I hope you can figure it out! Do you get gas or nausea associated with it? If so, it's possible it's histamine related.
I'm starting to think an anxiety med would benefit me. Too bad one doesn't exist without side effects. Sadly I can't be on "vacation" everyday.
I hope you can figure it out! Do you get gas or nausea associated with it? If so, it's possible it's histamine related.
Martha E.
Philippians 4:13
Jul 2008 took Clindamycin for a Sinus infection that forever changed my life
Dec 2014 MC Dx
Jul 15, 2015 Elimination Diet
Aug 17, 2015 Enterolab Test
Dec 2015 Reflux
Sept 2016 IC
Philippians 4:13
Jul 2008 took Clindamycin for a Sinus infection that forever changed my life
Dec 2014 MC Dx
Jul 15, 2015 Elimination Diet
Aug 17, 2015 Enterolab Test
Dec 2015 Reflux
Sept 2016 IC
Erica,
The key is that the triptans are selective serotonin receptor agonists, meaning that triptans work by stimulating serotonin. And the intestines contain approximately 95 % of the body's supply of serotonin.
Tex
The key is that the triptans are selective serotonin receptor agonists, meaning that triptans work by stimulating serotonin. And the intestines contain approximately 95 % of the body's supply of serotonin.
The Gut-Brain Link: How Your Headaches Might Stem From Your DigestionSerotonin: Not just for depression anymore
It is believed that the digestive system is very complex in terms of its production of neurotransmitters, including serotonin. The gut has specialized cells that release serotonin, which is a key neurotransmitter in the migraine world. In fact, it is believed that most of our serotonin is produced in the gut. (8) FYI, this is the neurotransmitter linked to the success of triptan medications, the largest class of FDA-approved abortive medications for migraine.
Triptan medications work on serotonin receptors to help with migraine pain. Interestingly, many patients who had not gotten relief from traditional irritable bowel syndrome treatment responded well to antidepressants that work on serotonin. In fact, the gut has at least seven different receptors that respond to serotonin. [9]
With all of this information, a few years ago I began asking patients to not only discuss their neurological complaints that affected their brains, but also the complaints that affected their digestion. I was shocked to learn how many of them had been suffering with digestive issues for years before their headaches began. Of course, most never thought that the gut and its often zany antics could affect the brain.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
That was an enlightening article Tex, in your opinion or your suggestion how do we help our gut get proper Serotonin? To me that is the key to the lock behind the mystery because I can't deal with the side effects of the 'don't give a damn attitude' I get while on sumatriptans, lol.
Martha,
Can't say I get any gas or nausea from the sumatriptan...been watching that histamine rather closely lately too
Martha,
Can't say I get any gas or nausea from the sumatriptan...been watching that histamine rather closely lately too
To Succeed you have to Believe in something with such a passion that it becomes a Reality - Anita Roddick
Dx LC April 2012 had symptoms since Aug 2007
Dx LC April 2012 had symptoms since Aug 2007
Erica,
As Gabes often emphasizes, the "B" vitamins, especially vitamin B-6 is important for maintaining health of the neurological system. And folic acid, vitamin D and magnesium are also essential for serotonin production. Recommended foods include greens, fish, poultry, and lean beef. Grain substitutes that are relatively high-protein carbs, such as amaranth, buckwheat, millet, and quinoa are claimed to help, but some of us have problems with some of these, possibly due to cross-contaminated flour.
The tryptophan in turkey, sunflower and pumpkin seeds is a precursor to serotonin. But it's claimed that eating protein with carbs is counterproductive for serotonin production. I have a hunch though that this claim refers to serotonin production in the brain, not in the gut.
Here's a link to an article that appears to offer a fairly thorough discussion of the issue:
Understanding Our Bodies: Serotonin, The Connection Between Food and Mood
Tex
As Gabes often emphasizes, the "B" vitamins, especially vitamin B-6 is important for maintaining health of the neurological system. And folic acid, vitamin D and magnesium are also essential for serotonin production. Recommended foods include greens, fish, poultry, and lean beef. Grain substitutes that are relatively high-protein carbs, such as amaranth, buckwheat, millet, and quinoa are claimed to help, but some of us have problems with some of these, possibly due to cross-contaminated flour.
The tryptophan in turkey, sunflower and pumpkin seeds is a precursor to serotonin. But it's claimed that eating protein with carbs is counterproductive for serotonin production. I have a hunch though that this claim refers to serotonin production in the brain, not in the gut.
Here's a link to an article that appears to offer a fairly thorough discussion of the issue:
Understanding Our Bodies: Serotonin, The Connection Between Food and Mood
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.