I got a copy of my biopsy results: "Sections show multiple fragments of colonic os of intact crypt architecture. Focally a few neutrophils infiltrate some crypts. Much of the remaining fragments are unremarkable. Granulomas, dysplasia or malignancy are not seen."
This doesn't even sound very significant at all & is it just me, or if that description SUPER vague!? "A few neutrophils infiltrate some crypts"...seems very nonspecific. The provider told me I have microscopic colitis and put me on Lialda for at least 6 months. I am getting a second opinion today. Any feedback?
Biospy Results?
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
Pathologists tend to use vague terminology. Focusing on (or citing) a few lines of findings from the pathology report rather than considering the entire report can be misleading.
The neutrophils can be a good sign (they're a protective lymophocyte) or a bad sign (excessive numbers can be associated with Cronn's disease or ulcerative colitis). Sometimes they are associated with MC, but otherwise it is indeed an unremarkable observation. The fact that your crypt architecture is intact rules out Crohn's disease or UC. There should be some mention of an elevated count of other lymphocytes or thickened collagen layers in the lamina propria to justify a diagnosis of MC. At least that's my strictly unprofessional opinion.
Tex
The neutrophils can be a good sign (they're a protective lymophocyte) or a bad sign (excessive numbers can be associated with Cronn's disease or ulcerative colitis). Sometimes they are associated with MC, but otherwise it is indeed an unremarkable observation. The fact that your crypt architecture is intact rules out Crohn's disease or UC. There should be some mention of an elevated count of other lymphocytes or thickened collagen layers in the lamina propria to justify a diagnosis of MC. At least that's my strictly unprofessional opinion.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.