I am lost! Help!
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
I am lost! Help!
I just got back from a visit with my gi. I am looking at the test results I received from my last visit. Just some of them...I can't figure out what they mean. I know these and my biopsies got be to my cc diagnosis but, what does it mean something else could go wrong because I have some of the variants and inflammation markers? My doc explained in what I will sware was Latin and the more I Google the less I understand. Is there somewhere I can look these up that is understandable? Or is their someone I can ask? I am so lost I just want to cry. Any help will be greatly appreciated. Thanks!
Sure, I can read some "doctorspeak". I say "some", because every medical specialty seems to have it's own preferred lexicon and syntax. If you don't want to post it for public viewing, copy it into a PM and send it to me, or attach it to an email and send it to me. You can open a form to use for either one by clicking on the appropriate button at the bottom of this post.
Tex
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
It's these test results I don't get. I can't even tell if they should be meaningful to me but, somehow they seem to be important. But no one can explain them???? It might be because I am so overwhelmed right now but, I just can't seem to understand anything I am reading about them. Thanks for your help.
Result. Range
C reactive protein. 0.43 0.00-0.50
Sedimentation rate 16 0-20
Anti-A4-Fla2 lgG 48.8 <32.4
ELISA
VEGF. 403. <393
SAA 30.4 <22.9
EMC1 Variant Detected - Heterozygous rs3737240(C;T)
NKX2-3 Variant Detected - Heterozygous rs10883365(A;G)
STAT3 Variant Detected - Heterozygous rs744166(A;G)
there are more tests but they all came back with in range. I will gladly share them if they would help in understanding all this. Thank you for any insight.
Result. Range
C reactive protein. 0.43 0.00-0.50
Sedimentation rate 16 0-20
Anti-A4-Fla2 lgG 48.8 <32.4
ELISA
VEGF. 403. <393
SAA 30.4 <22.9
EMC1 Variant Detected - Heterozygous rs3737240(C;T)
NKX2-3 Variant Detected - Heterozygous rs10883365(A;G)
STAT3 Variant Detected - Heterozygous rs744166(A;G)
there are more tests but they all came back with in range. I will gladly share them if they would help in understanding all this. Thank you for any insight.
These first five are all measures of inflammation and the last three are gene mutations.
Your CRP result is normal (rarely is it elevated for an MC patient) and so is your SED rate. As I recall, my SED rate was slightly elevated at one point during my recovery.
The anti-A4-Fla2 test detects antibodies (IgG antibodies) to the particular flagellin named in the test (A4-Fla2). A flagellin is the whisker-like external appendage on many types of bacteria. They're made of a protein that causes an immune system reaction for many IBD patients, so it's not surprising that your result would be elevated.
VEGF stands for Vascular endothelial growth factor, which may be elevated for many types of IBDs, injury, infection, autoimmune disease, or tumors but it primary indicates inflammation.
SAA stands for Serum amyloid A, and it's just another way to detect tissue injury and inflammation and it's often elevated in IBD patients.
I don't know anything about the gene tests. Those results just represent certain SNPs. I would be surprised if they actually mean anything, because gene mutations simply affect risks, they don't really indicate any disease or a particular problem.
So really all these tests measure inflammation — they just confirm that you have an IBD. I don't understand why your doctor would order all these inflammation tests when he already knows that you have an IBD.
I hope this is helpful.
Tex
Your CRP result is normal (rarely is it elevated for an MC patient) and so is your SED rate. As I recall, my SED rate was slightly elevated at one point during my recovery.
The anti-A4-Fla2 test detects antibodies (IgG antibodies) to the particular flagellin named in the test (A4-Fla2). A flagellin is the whisker-like external appendage on many types of bacteria. They're made of a protein that causes an immune system reaction for many IBD patients, so it's not surprising that your result would be elevated.
VEGF stands for Vascular endothelial growth factor, which may be elevated for many types of IBDs, injury, infection, autoimmune disease, or tumors but it primary indicates inflammation.
SAA stands for Serum amyloid A, and it's just another way to detect tissue injury and inflammation and it's often elevated in IBD patients.
I don't know anything about the gene tests. Those results just represent certain SNPs. I would be surprised if they actually mean anything, because gene mutations simply affect risks, they don't really indicate any disease or a particular problem.
So really all these tests measure inflammation — they just confirm that you have an IBD. I don't understand why your doctor would order all these inflammation tests when he already knows that you have an IBD.
I hope this is helpful.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Thank you. Maybe the reason he did all the double speak that made no sense is these are tests that said what we already knew. You lifted a great weight from me. Thank you! I knew the more I stayed in my head with this the less sense anything I read was going to make. Now I can sleep. Thank you again!
