Has anyone had any success taking these drugs on a maintenance level in controlling CC? I am currently tapering budesonide, taking 6 mg a day, while maintaining a low fiber, GF and dairy free diet. Mixed success. I recently talked to an ulcerative colitis sufferer who achieved complete remission by using mesalamine suppositories for six weeks. Anybody tried suppositories? I know—yucky. But if effective, maybe worth it.
Thanks for your responses!
Mesalamine taken with cholestryamine
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charliemudcat
- Posts: 18
- Joined: Wed Sep 20, 2017 4:02 pm
- Location: Minnesota
Hi Katie,
I see that no one has responded to your post. That may be because these days not many members here seem to use mesalamine any more. They usually maintain a safe diet and taper off the budesonide very, very slowly so as not to trigger a relapse because of the rebound effect that normally follows ending a budesonide treatment regimen.
Suppositories work well for UC primarily because UC inflammation is concentrated at the distal end of the colon (from the Sigmoid colon to the rectum). By contast, MC inflammation is usually found in scattered patches from the rectum all the way to the terminal ileum. In fact, it often predominantly affects the ascending colon and the terminal ileum, so suppositories would probably be far less effective for CC.
But that's just my strictly unprofessional opinion.
Tex
I see that no one has responded to your post. That may be because these days not many members here seem to use mesalamine any more. They usually maintain a safe diet and taper off the budesonide very, very slowly so as not to trigger a relapse because of the rebound effect that normally follows ending a budesonide treatment regimen.
Suppositories work well for UC primarily because UC inflammation is concentrated at the distal end of the colon (from the Sigmoid colon to the rectum). By contast, MC inflammation is usually found in scattered patches from the rectum all the way to the terminal ileum. In fact, it often predominantly affects the ascending colon and the terminal ileum, so suppositories would probably be far less effective for CC.
But that's just my strictly unprofessional opinion.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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charliemudcat
- Posts: 18
- Joined: Wed Sep 20, 2017 4:02 pm
- Location: Minnesota
Thanks, Wayne. I am continuing my slow withdrawal from budesonide along with my diet changes. Still looking for a fallback that isn’t steroidal in the event of another onset, once i’m Off the budesonide.
I appreciative your lay opinion as you’re more knowledgeable than most professionals in my experience.
Katie
I appreciative your lay opinion as you’re more knowledgeable than most professionals in my experience.
Katie
Katie
Thanks, I appreciate your kind words.
For some members, taking an antihistamine each day for a couple of weeks (or as long as you feel it is necessary), starting when the budesonide treatment ends, helps to maintain remission during this critical period.
Wayne
For some members, taking an antihistamine each day for a couple of weeks (or as long as you feel it is necessary), starting when the budesonide treatment ends, helps to maintain remission during this critical period.
Wayne
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
I reread your thread. You may need to stay on 6 mg for awhile. Don't rush it. Some folks are on 6 mg for 2-3-4-5-months.
If you are having mixed success hang out on 6 mg longer to allow more healing to take place.
Too fast of taper=high incidence of relapse.
Very long slow taper gives much higher success rate of getting off of budesonide.
If you are having mixed success hang out on 6 mg longer to allow more healing to take place.
Too fast of taper=high incidence of relapse.
Very long slow taper gives much higher success rate of getting off of budesonide.