I think there is a couple of factors that have contributed to external symptoms;
- alcohol depletes magnesium and interrupts methylation cycle (ie disrupts use of B6 by the body)
- found the info below, and in line with your candida, the imbalance in your gut could be contributing to the increased histamine/DAO etc
https://paleoleap.com/histamines/
The biggest nonfood source of histamines in most people’s bodies, though, is their gut flora. Some kinds of bacteria produce histamines, while others degrade them. Too many histamine-producing bacteria can fill up your “sink” faster than DAO can empty it. If you think about it, this makes perfect sense: it’s the same reason why fermented foods are off the table, only the reaction is happening internally instead of externally.
The importance of gut flora in creating and destroying histamine can give rise to a sudden onset of histamine intolerance later in life, if you take antibiotics or make a drastic change to your diet. When the gut flora start growing back after this kind of trauma, the environment is ripe for bacterial overgrowth problems, and a predominance of histamine-producing bacteria might be just one of those issues. And in a cruel coincidence, the probiotic fermented foods that you eat to heal your gut are all high in histamine, so they only make the problem worse.
And the gut problems don’t stop there. DAO, the “emergency drain” in the histamine sink, is mainly produced by the mucous lining the intestinal wall. If the lining of the gut is irritated (by inflammatory foods like grains and legumes), DAO production decreases, and the symptoms of histamine overload only get worse.
GEESH!!! my jeans are killing me at work today because my last wheal erupted right at the bend in my hip/leg near the pelvic.....ARGH that hurts to sit today.
Hello! This is my very first post (I think), and I need help! I am a Type1 Diabetic and for the past several days have been in a MAJOR flare of MC. Everything that is good for DM (diabetes) is terrible for MC, and vice versa. Yesterday my blood sugar dropped to 48 (WAY TOO LOW, RANGE IS 80-120), and things I would normally eat to bring it back up to a normal range sent me running to the bathroom.
