Ketogenic diet appears to prevent cognitive decline in mice, study finds"While diet modifications, the Ketogenic Diet in particular, has demonstrated effectiveness in treating certain diseases, we chose to test healthy young mice using diet as a potential preventative measure," Lin said. "We were delighted to see that we might indeed be able to use diet to mitigate risk for Alzheimer's disease."
Interestingly, according to the original article, the ketogenic diet reduces some of the known risk markers of Alzheimer's. Here's a quote of the conclusion reached in the original research article and a link to the full article:
Neuroimaging Biomarkers of mTOR Inhibition on Vascular and Metabolic Functions in Aging Brain and Alzheimer’s DiseaseConclusion
In this review, we discussed the neuroprotective effects of mTOR inhibition in aging and AD. Specifically, rapamycin is a preventative, and possibly a treatment, for the effects of the AD phenotype observed in APOE4 and hAPP(J20) transgenic mouse models of AD; CR and KD can enhance brain vascular functions and shift metabolism in young healthy mice; and CR can preserve brain metabolic and vascular functions in aging. We summarize these findings in Figure 1. As the quantitative PET and MRI neuroimaging methods used in these studies in animal models can be translated into human studies, they will be greatly useful in future studies to examine the effects of these mTOR-related interventions in preventing brain function declines associated with aging and neurodegeneration in clinical trials.
And if a diet very low in carbohydrates helps to preserve the health of the brain, it doesn't take much of a stretch of the imagination to recognize that carbohydrates in the diet almost surely play a part in the development of various brain diseases that lead to cognitive and memory impairment. Remember, these diseases originated with the neolithic period in our history, when agriculture was developed.
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