Great Histamine gut explanation-link to explore more

[Erica P-G]

https://factvsfitness.com/what-causes-h ... lerance%3F

(excerpt from factvsfitness.com)
So What Is A Histamine Intolerance Anyway.....
Overall, histamine intolerance comes down to an imbalance in your internal histamine levels.

Histamine levels in the body are simply higher than they should be and, much like during an allergic reaction, these high levels of histamine are causing a response which you’re experiencing as histamine intolerance symptoms.

Although many factors contribute to determining internal histamine levels, there are 4 major factors involved in the underlying cause of histamine intolerance.

What Causes Histamine Intolerance? Four Major Factors:
Level of Histamine Consumption - histamine is consumed mainly through food, but also through environmental and plant exposures.
Amount of Bacterial Production of Histamine - Bacteria produce histamine by converting the amino acid histidine into histamine. Even your probiotics can actually contribute to higher histamine levels - so, ensure you are taking a histamine safe probiotic with bacteria that won't produce more histamine.
The Amount of Histamine Released from Mast Cells - Histamine is typically released from mast cells in response to allergens, however if mast cells are unstable, histamine can be released at higher-than-normal levels.
The Rate of Enzymatic Degradation - Histamine is degraded by specialized histamine degrading enzymes such as diamine oxidase (DAO) and histamine N-methyltransferase (HNMT). Low levels of these enzymes due to genetic or other factors can result in a slower-than-normal rate of histamine degradation.
In a perfect digestive system, the levels of histamine consumption, production and release will balance with the levels of histamine degradation.

However... in a compromised digestive system, such as that of people with IBS or gut issues, factors such as bacterial imbalances and enzyme insufficiencies can throw off this balance, resulting in extremely high levels of histamine.

These high histamine levels can cause inflammation that can impact the bowel, therefore producing or exacerbating digestive issues and creating food sensitivities.

Additionally, a histamine intolerance may be behind seemingly unrelated symptoms such as skin rashes, headaches, fatigue, respiratory symptoms or even symptoms that mimic allergic responses like hives and congestion.