Why Magnesium and VitD are important

[Gabes-Apg]

there was an article on the old forum board that explained this very well - I have done some digging on the web and can not find the original article

I did find this presentation - not too much science but it explains why Vit D3 and magnesium are important.
you need good magnesium levels to effectively use the Vit D3

https://d347awuzx0kdse.cloudfront.net/a ... 31eb402e4e

this is proven from peer reviewed studies
__________________________________________

Improved Mg status leads to an increase in
Vitamin D binding protein, and in turn, an
elevated transport of Vitamin D to the liver
and 25 (OH)D to the kidney.
https://bmcmedicine.biomedcentral.com/a ... 015-11-187

Mg is required for the binding of Vitamin D
to its transport protein, Vitamin D binding
protein. Also, conversion of Vitamin D by
hepatic 25-hydroxylation and renal 1alphahydroxylation into the active, hormonal
form, Calcitriol (1,25(OH)2D is Mgdependent.
https://www.ncbi.nlm.nih.gov/pmc/articl ... rients-07-
05388.pd


My personal experience, and observations after being part of this forum for 11 years, for may people the medication and/or diet will have limited scope of success if you are deficient in Vit D3 and magnesium.

[Gabes-Apg]

https://www.nutraingredients.com/Articl ... -effective

due to copyright i can not copy key points from this article
please take 5 mins to have a read

[Gabes-Apg]

https://www.healthbyprinciple.com/blogs ... une-system

Vitamin D goes through a series of reactions in order to become an active substance in the body; it picks up oxygen, changes its structure, and travels to different parts of the body. As it moves through the process, it receives help from a number of different biological molecules, including magnesium.

Magnesium acts as a co-factor in the vitamin D activation reactions that take place in the liver and kidneys. It appears that all of the enzymes needed to metabolize vitamin D require magnesium to do so.

And it seems that the assistance goes both ways. Some studies have seen that vitamin D may stimulate the intestinal absorption of magnesium, helping the magnesium to take effect in the body. Therefore, magnesium derives some of its immune system benefits partly from its influence on vitamin D activity

[Gabes-Apg]

and thanks to Covid - the importance of Magnesium and Vit D3 for the immune system is getting some mainstream coverage!
us here at this forum have known this for years, but more mainstream medicine organisations are putting time and money into this research

https://www.saintlukeskc.org/about/news ... infections

Another study tested 40 COVID-19 patients who were asymptomatic or mildly symptomatic. Some took vitamin D supplements for two weeks until they achieved a healthy blood level, others took a placebo. After three weeks, three times as many patients in the vitamin D group tested negative for COVID-19 than those who took the placebo.

Low levels of magnesium and vitamin D are a common characteristic in a majority of patients with COVID-19. Getting these levels back into the normal range is a safe and inexpensive over-the-counter treatment that can strengthen immune function. Dr. DiNicolantonio’s and Dr. O’Keefe’s paper concluded that magnesium and vitamin D should get special consideration in the general population during the pandemic.

[tex]

Excellent, and right on target. This information is vital for anyone who is trying to control any autoimmune disease. And it's especially important for dealing with microscopic colitis and other IBDs.

Great job, Gabes.

Tex

[jennifer]

WOW!!! Thank you Gabes, that was super informative!
I dont know why dr's refuse to ignore something so vital to the human body.
But, like you said, with Covid, maybe now it will start to grab their attention.
Jen

[Gabes-Apg]

Dosages
(thanks Tex I copied some of your text from the other discussion)

The vitamin D dose needed will depend on your particular circumstances, such as how much sun exposure you get, and your stage of healing. The average individual uses 5000 IU per day of vitamin D, but most of us need more, when we begin our recovery, because we're deficient. MC depletes vitamin D and magnesium. We can get vitamin D from food and sunlight, but almost everyone has to take a supplement in order to get enough these days, because we don't spend anywhere near as much time out in the sun, as our ancestors did. A few months after you begin taking vitamin D, it's a good idea to have your level checked, to determine whether you need to take more or less, in the future.


The recommended RDA for magnesium is a good place to start for most of us. That would be 400 mg for men, and 320 for women.
medication, hormones, coffee deplete magnesium so you may need more each day than the RDA

some of us can't tolerate oral magnesium when we're recovering from MC, because too much of it can trigger diarrhea for those of us who are extra-sensitive to it. So those of us in that situation have to use magnesium oil or lotion on our skin. Alternatively, we can do foot soaks in Epsom salts / magnesium chloride , or we can add a cup of Epsom salts to our bathwater and soak for 15 or 20 minutes several times a week.
If you can tolerate oral magnesium supplements, that's by far the easiest. We've found that the best oral supplement for magnesium is magnesium glycinate, but don't take it all in one dose, because we can only absorb a limited amount at any given time. I take 300 mg of magnesium glycinate daily, divided up as one tablet after each meal.

If you are deficient in either or both Vit D3 / magnesium - it can take 8-30 weeks to resolve deficiencies.