Butyrate supplement

Feel free to discuss any topic of general interest, so long as nothing you post here is likely to be interpreted as insulting, and/or inflammatory, nor clearly designed to provoke any individual or group. Please be considerate of others feelings, and they will be considerate of yours.

Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh

Post Reply
Billy
Little Blue Penguin
Little Blue Penguin
Posts: 28
Joined: Thu Jul 15, 2021 10:12 am

Butyrate supplement

Post by Billy »

Just curious has anyone here tried a Butyrate supplement? Just curious.
User avatar
Gabes-Apg
Emperor Penguin
Emperor Penguin
Posts: 8332
Joined: Mon Dec 21, 2009 3:12 pm
Location: Hunter Valley NSW Australia

Re: Butyrate supplement

Post by Gabes-Apg »

My observation from my time being part of this group (11 years) and what I have learnt in the functional medicine fields

Supplements /herbs to help promote good bacteria will have limited scope of success while there is ongoing inflammation in the gut.

the priority for good quality healing in MC world is to calm the inflammation cycle.
Gabes Ryan

"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
Billy
Little Blue Penguin
Little Blue Penguin
Posts: 28
Joined: Thu Jul 15, 2021 10:12 am

Re: Butyrate supplement

Post by Billy »

It’s not an herb. Here is some more info I pasted the link below.

What is butyrate and how is it made?
Interest in the microbiome is growing daily, and yet, accessible and reliable information about its functions can be hard to come by, as is the case for butyrate. This journey of discovery starts with a basic introduction to the microbiome, short-chain fatty acids (SCFAs, remember?) and, finally butyrate.

The microbiome is an ecosystem of bacteria, yeasts and other microscopic beings that live in the gut. It performs many functions, including the production, regulation and break down of small molecules that complement the physiological functions of the human body. For example, our gut bacteria produce fatty acids, vitamins and amino acids that have a range of beneficial effects for the body, from promoting healthy immune system function to maintaining the integrity of the gut lining.
In particular, one of these functions is to break down dietary fibre that has travelled through the digestive tract, because the human body can’t. This process, known as fermentation, yields a variety of metabolites including butyrate, an organic compound that belongs to the group of “short-chain fatty acids”. These health-promoting molecules are an important energy source for the body, providing anywhere from 5% to 15% of a person’s daily caloric needs.

Gut bacteria produce fatty acids, vitamins and amino acids that have a range of beneficial effects for the body.
Butyrate is the main fuel for the cells that line the gut, known as “colonocytes”, providing up to 90% of their energetic requirements. In other words, butyrate helps these cells fulfil their functions correctly, thus maintaining the integrity of the gut lining, called “mucosa”. In fact, “several studies have linked impaired butyrate metabolism with mucosal damage and inflammation in patients with inflammatory bowel diseases including ulcerative colitis and Crohn’s disease”.

https://atlasbiomed.com/blog/what-is-butyrate/
User avatar
tex
Site Admin
Site Admin
Posts: 35067
Joined: Tue May 24, 2005 9:00 am
Location: Central Texas

Re: Butyrate supplement

Post by tex »

Hi Billy,

I'm sure opinions vary widely on this issue, but here's my opinion:

If you spend time surfing the Internet, you'll find plenty of reasons to believe that microbiome management by taking supplements or probiotics is the key to a long and healthy life, barely short of finding the holy Grail. But those of us who've managed to control our microscopic colitis symptoms by diet alone, recognize all that fluff as a sales pitch for something that not only do we not need, but is very likely to interfere with our recovery, or at the very least, complicate our recovery.

The problem is, our gut biome is determined by our diet, our degree of inflammation, and our environment. If we change our diet, our gut biome will change drastically to reflect the change in foods. And as the inflammation associated with MC increases, our ability to properly digest food is severely compromised, resulting in poorly digested, or partly digested foods. These foods then attract opportunistic bacteria to ferment them (which is a nice way of saying to rot them), resulting in a drastic change in our gut biome profile.

Attempts to change that profile with antibiotics, probiotics, probiotics, or standing on our head, will have virtually no long-term effect. Within a matter of a week or two,our gut biome will revert right back to where it wants to be, based on our diet and our degree of Inflammation. We can waste all the money we want, trying to treat SIBO or any other gut biome disruptions, but our gut biome is going to go right back to Where it wants to be, because of natural selection.

Even the American Gastroenterological Association Institute changed their opinion to agree with me, way back in December of 2015. Now they recommend against the use of probiotics when treating microscopic colitis, reversing their previous opinion. The problem with probiotics and prebiotics is that they enhance the propagation of bad bacteria, just as well as they enhance the development of good bacteria. Consequently, they are just as likely to interfere with our recovery from microscopic colitis as they are to benefit our recovery. I've said it many times, and I'll say it again, "Less is more when treating microscopic colitis." The fewer items we put into our mouths when trying to recover from this disease, the less likely we will be to cause additional information, and the faster we tend to recover, on the average.

After we're in remission, then yes, we can probably tolerate probiotics and prebiotics. But the point is, we won't need them then. Published research shows that they provide absolutely no benefit for the average individual in the general population, who's in good health. In other words, they're just a waste of money for most people, and especially for MC patients. Manufacturing and marketing probiotics and prebiotic supplements are a multibillion-dollar industry. The problem is, the science showing that it's actually beneficial for general health, doesn't exist outside of the specialized studies financed by the industry itself, that always conclude how great the products work. Impartial studies show no benefits.

Re: butyrate supplements, just because butyrate compounds are present in the intestines, and appear to be part of the inflammation regulatory process, does not imply that supplements will provide any actual benefits. Assumptions of that type are almost always wishful thinking. It's not that easy. Chemical processes that are carried out within the body are complex and poorly understood. Attempting to modify them by using supplements is a bit like trying to fool mother nature, and has about as much success potential, on the average.

The bottom line is, "If you like to waste your money on supplements, often uncommon or exotic supplements probably won't hurt you (although sometimes they will), but rarely will they provide any significant benefits, at least this is true when treating MC.

Again, note that this is just my opinion, and there are others who probably won't agree. And please note that this opinion is as impartial as I can make it, because I don't make any money out of this position, one way or another.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
brandy
King Penguin
King Penguin
Posts: 2909
Joined: Sun Oct 16, 2011 9:54 am
Location: Florida

Re: Butyrate supplement

Post by brandy »

Hi Billy,

Most of us do better with fewer supplements.
Billy
Little Blue Penguin
Little Blue Penguin
Posts: 28
Joined: Thu Jul 15, 2021 10:12 am

Re: Butyrate supplement

Post by Billy »

Thanks Tex and everyone. I try to research everything. Probably my own worst enemy. Funny how these YouTube videos can be so convincing. Especially when were soooo desperate. Someone always has the magic pill. Love this board and the knowledge you guys bring. Thanks again.
Post Reply

Return to “Main Message Board”