Presentation and looking for advice

[Gabes-Apg]

So I believe that, for my case, the stabilization issue is very important, do you guys agree? I think both of you are going on that direction, aren't you?
ongoing inflammation triggers the immune system
Treating the root cause of what is inflaming the body, histamine, toxins, stress, wrong food ingredients is one aspect
Fixing nutritional deficiencies that are causing imbalance, and that are required for the body to detox and heal are very important

Healing the body is like renovating a house - if you dont fix the root cause issues that are under the floor, in the walls etc then it may look ok but it won't stand test of time
the suggestions we are making are foundational steps to wellness

Regarding blood analysis of nutrients like B Group zinc etc

1. current testing via blood protocols are not an 'accurate' indicator of levels in the body. (muscle testing is only accurate way albeit not readily available nor affordable)
2. blood testing indicators are reliant on supplementation stopping at least 48 hours before testing
3. you may have these items in the body, but is the body USING the nutrients properly.
(like the Vit D3 magnesium relationship all nutrients have cofactors)


regarding dosages
Dosage requirements are VERY individual especially for things like zinc
depends on if you are male or female, age, other health issues, diet and lifestyle, even factors such as where you grew up and were you exposed to toxins that deplete things like zinc

Example; the current recommended daily RDI for zinc is 11mg for men and 8mg for women.
in my functional wellness journey I have determined that a) I was born with high levels of toxic metals and have been zinc deficient my whole life b) immune issues my whole life. c) have a health issue that depletes zinc and P5P (active form of B6).
when we first figured this out - my zinc dosage was 120mg to correct the deficiency, now my maintenance dose is about 90mg per day

Other people with same issue may only need 40mg or 60mg of zinc as maintenance dose, it all depends on the factors I mention above
male or female, age, other health issues, etc

My advice 'listen to your body'. start with 20mg or 30mg of zinc piconolate. do that for 8 weeks see if there is an improvement
there is a good Thorne active B's supplement that has active form of B12. B6 etc take the recommended dose of that

For my case with the zinc, it took me 3 years to clear the cells of the toxic metals that had 'hogged' the space that zinc was meant to hold in the cell
once we cleared the toxins, the body could absorb the zinc and start using it properly.
First time in my life I have healthy strong nails. (if they start to break I increase the zinc) I have learnt to listen to my body, what the niggling symptoms mean, what the good things like hair and nails are indicating

Basic nutritional deficiencies take about 8 weeks of good dosages to fix
medium level deficiencies take 10 - 20 weeks.
long term deficiencies can take longer. It took me 9 months of oral and dermal magnesium to fix that deficiency, as I mentioned about 3 years to get the right zinc balance and know what my maintenance dose should be
There is no 'one size fits all' solution

I used various functional approaches to assess the issues, and fix them.
hair analysis, genetic analysis, methylation cycle analysis, functional testing and assessment, LOADS of research
I purchased nutritional text books to understand what depletes the nutrients, what cofactors are needed to help the body use them etc

[Gabes-Apg]

Functional article that may assist with the topics I mention above

https://www.westonaprice.org/health-top ... #gsc.tab=0
Adrenal Fatigue
All chronic illness includes chronic fatigue and adrenal fatigue, whether you feel tired or not. A lot of my patients will say, “Oh, I have lots of energy,” but they do not or they would not be chronically ill. There is no conventional medical treatment for adrenal fatigue unless you have reached the point of total failure, at which time you are put on cortical supplements for the rest of your life. Therefore, like the issue of toxic metals, if adrenal fatigue is not tested for, it is not discussed.

These two problems—adrenal fatigue and toxic metal buildup—are strongly related because you cannot excrete metal without good adrenal function. Adrenal function needs to be pretty close to normal or you will start retaining metals, because the adrenal glands have such a big part to play in the proper handling of metals in the body.



Local Variations
What happens next depends on many variables— the types of metals to which you are exposed, and how much, and even where you live. I find very interesting variations in the hair tests, depending on where people live. In California, for instance, I primarily see aluminum toxicity; apparently there is a lot of aluminum in the area. Aluminum is a very common metal, comprising up to 14 percent of the earth’s crust, so it is in the dust and in the air.

Aluminum is also an additive in anti-perspirants. I have a theory that in warm climates, where people use a lot of anti-perspirants, they are exposed to a lot more aluminum than people living in colder climates.

On the East Coast, I see more problems with cadmium, mercury and lead, the heavy metals. On the West Coast, if someone shows mercury, you can bet they have been eating fish twice a week and have been for a while. If they aren’t eating fish, they don’t show mercury even if it is in their mouth. I don’t know why, but that is what I have found.

Interesting Facts About Zinc
Zinc is rapidly lost under stress.
Zinc is essential for protein synthesis. Low zinc status leads to problems with hormone production, healing and growth.
Zinc is rapidly used up after injury or surgery as it is needed for protein synthesis.
Because they are growing so rapidly, teenagers are very prone to zinc deficiencies.
Zinc deficiency affects the immune system. Zinc kills a lot of viruses on contact. Those deficient in zinc may be susceptible to viruses.
Zinc is a sedative and calming mineral for the mind. GABA, which is an inhibitory calming neurotransmitter, is zinc dependent.
The body needs zinc to build protein so the skin and nails very often reveal zinc status. Stretch marks are always a sign of low zinc, at least at the time when they were formed.
Zinc is essential for production of adrenal cortical hormones, especially aldosterone and cortisol.
Zinc is critical for normal appetite, smell and taste. A sign of zinc deficiency is lack of appetite in the morning, or even nausea.
When zinc is low and copper is high, the body will dump copper with consumption of meat, a high-zinc food. For some vegetarians, the copper dump can be so strong, they literally throw up any meat they try to eat. People in this situation will first need to lower their copper levels before they can eat meat. Then they will need to begin with very small amounts of white chicken meat and only very gradually introduce red meat.
The ideal ratio of copper to zinc is 1:8 in favor of zinc.
Some plant foods contain zinc, but when they do, it is usually accompanied by a lot of copper. Animal foods are the only good source.

[tex]

Cauliflower, brocolli, and kale are not normally classified as hike histamine foods. So I suspect you get the impression that they're causing a histamine reaction simply because once histamine reactions begin, they tend to typically reoccur on a daily basis (often at similar times of the day(. This pattern of reactions can go on for weeks as histamine levels slowly decline in your body, despite the fact that you are not ingesting any high histamine foods.

Could I being reacting to my own microbiota?

Not likely, unless you're taking a probiotic.

Tex

[dps231]

DAO depends on vitamin B6 to function. If there is shortage of B6, the enzyme is practically useless.

you may have these items in the body, but is the body USING the nutrients properly.

So Gabes are you saying that DAO could be useless despite being at correct levels? iteresting

I'll try active's B supplements then.

Tex:

So I suspect you get the impression that they're causing a histamine

Yes, maybe you're right

Not likely, unless you're taking a probiotic.

No, I'm not taking any probiotic right now, but I've been trying this year, 3 months ago.

---
I want to share with you some very complete stool analysis I made at Jan21. They cost a fortune.
I want to point that I was taking NAC (to stabilize mast cells), Zinc (without copper... ), VitD, Calcium and Mg.
I undestand zinc and calcium levels were high because of supplementation.
But something nobody talked about was Sn levels, they are no sense!. Where it come from? I hypothesis of mine is that I passed years eating canned food every day... I don't know.


I'm starting to think about these nutrients having something to do with my tendon issues:
I work out, and after that every tendon I used during the session feels too tight and painful, it lasts days.

stools.jpg (194.83 KiB) Viewed 623 times

[tex]

Were you taking a calcium supplement? The calcium level of that sample was very high. Taking calcium supplements raises the risk of cardiovascular issues. If you want to absorb more calcium, take vitamin D and magnesium, not calcium. There's more than enough calcium in your diet. If your blood level shows low calcium, you're simply not absorbing it because of a vitamin D or magnesium deficiency.

High levels of trace elements/heavy metals, such as tin' are often due to deficiencies of other vital vitamins or minerals. When certain mineral ratios get out of balance, such as the zinc/copper ratio, for example, it tends to cause other deficiencies or excess levels. Certain minerals have to be kept in balance. It's difficult to say where the high Sn level originates. For all I know, we may all have the problem, because that's one thing that we never, ever check. But It could be due to a genetic defect. I have no idea how common levels in that range might be, but your theory may be correct: that you slowly accumulated it, because you are unable to eliminate it from your body normally.

Gabes is probably better acquainted with issues such as heavy metal accumulation, but I get the impression that it's usually due to a vitamin or mineral deficiency, or a mineral ratio imbalance. Sorry that I couldn't be more helpful.

Tex

[dps231]

Regarding calcium, that's funny because always I take budesonide doctors also put me on vit D plus calcium, if fact its a pill with both of them together. We aren't in good hands omg!

[dps231]

A fast search on google and yes, tin seems to interfere with zinc and copper absortion.
This has reminded me that when I was a child (10 years) I had a lot of grey hair. In fact this was a big complex for me, which led to psychological problems after a while. Is grey hair and copper related?

Let see if Gabes can throw light on this.

[Gabes-Apg]

If these results are based on poop - it is what your body is clearing. It is not an accurate indicator of what is happening in the body

zinc might be high because you are not absorbing it all -

There is no one technique to clear all heavy metals. and no one test will show all heavy metals
some heavy metals are best assessed via urine, some hair, others blood or muscle testing.
I am not familiar with Tin as excess heavy metal so am limited as to what info I can share

quick google
the most common source of tin compound that can cause toxicity is toothpaste ingredient Stannous Flouride, and it can also be soaps, colouring agents, food additives. It is also part of plastic manufacture (so if you are reheating food in plastic container in microwave you could be getting additional amounts of tin)
Tin can also be in soils and ground water depending on where you have grew up and lived.
Also remember you can be born with toxic metals so review where your parents grew up and worked.

[tex]

As you're probably aware, the reason doctors prescribe calcium with vitamin D when they prescribe budesonide is because budesonide is associated with osteoporosis. But the reason budesonide is associated with osteoporosis is because it's almost always prescribed to patients who have IBD's, and budesonide depletes vitamin D and magnesium. I have little doubt that virtually every patient who has an IBD is also sensitive to gluten, and that's the reason why they are at risk of developing osteoporosis.

And doctors are finally beginning to realize that vitamin D is needed to allow the body to absorb calcium, although they're still not cognizant of the fact that magnesium is required to activate the vitamin D, so that it can increase calcium absorption in people who are magnesium deficient.

But the bottom line is that if you are carefully avoiding gluten, and keeping your vitamin D and magnesium levels up, then you're eliminating the reason for the increased risk of osteoporosis, so you do not need extra calcium in your diet — virtually everyone's diet already contains more than enough calcium, if they have adequate vitamin D and magnesium levels, so that they can absorb it. If they don't have adequate vitamin D and magnesium, then they can take all the magnesium they want, but it will do them little good, because it will simply go right through them into the toilet.

Tex

[Gabes-Apg]

premature greying hair is generally related to B12 deficiency and zinc deficiency

[dps231]

Gabes, I looked at Thorne's B supplement and it has an absurd amount of b12! In the past I was taking a similar active B supplement from Lamberts and after a month I started to experience insomnia. I'm scared of B group since then.

Tex. Do you take b6 with C,Mg and Zn also?

Do I have to take b6/p5p with the whole group?

[dps231]

I've being reading about Zinc and glutamatergic system. As you know I have tendency to insomnia. Some things that triggers that are L-glutamine or Glycine.

And know I've found this interesting article:
Zinc in the Glutamatergic Theory of Depression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790399/

[tex]

Here are a few facts to consider:

1. Type A personalities tend to over-think every issue, and worry about everything. They're unable to just let go of anything they view as a problem.
2. Most MC patients have type A personalities.
3. Stress is a major trigger for MC.
4. When I first developed MC, I only took a few, cheap, vitamins, and those were in the inactive form. Fast-forward about 10 years, and I began to have balance problems and other neurological issues such as TIAs. I was diagnosed with Parkinson's disease, as a result.
5. When I began to research those health issues, I realized that I was deficient in vitamin B12, vitamin D, magnesium, etc.
6. After taking the methylated forms of numerous vitamins for a few months, I was undiagnosed with Parkinson's disease.
7. When I developed MC, I began to have insomnia problems.
8. As I age, the insomnia problems seem to be more persistent.
9. Usually, I can get at least a few hours of sleep before I wake up and can't get back to sleep. I simply get up, and start the day, and the next night I'll be able to sleep.

Tex. Do you take b6 with C,Mg and Zn also?

Every morning, among others, I take one capsule of Thorne Methyl Guard Plus, one capsule of Solaray 1000 mg time release vitamin C, 300 mg of Doctors Best Magnesium Glycinate (actually, it's divided up during the day as a 100 mg tablet after each of three meals) and one capsule of Solaray zinc/copper in the proper ratio.

I worry about nothing. My mother was a nervous wreck all her life, because she worried about everything. I'm sure she had MC, because she had the same symptoms I had when my MC was active, but back in those days, none of us had any idea what was going on, and her doctors certainly didn't have a clue, even though she had to go to the emergency room occasionally because of a severe potassium deficiency, and the older generation didn't talk about issues such as diarrhea. So she suffered in silence. I swore that would never happen to me, and although it took years, today, I worry about nothing. When an issue comes up, I research it, think about it for a few hours, act on it (if action is warranted), and then forget about it.

I'm 81 now, and my routine blood test results make my doctor smile, because they're exemplary.

Tex

[dps231]

Most MC patients have type A personalities.

I agree, at least talking about me

When you guys say to be deficient in all these vitamins and minerals, do you really have blood analysis where this is shown?
I mean, I've never been officially deficient at any.
I know about magnesium not been correctly measured, but I don't know nothing about the rest of them.
I want to do it right, and not create new problems or waste money.

For example, this is from April21 (not always include these parameters):
Calcio 9.6 mg/dl (8.6 - 10.0)
Hierro 116 μg/dl (33 - 193)
Vitamina B12 618 pg/ml (197 - 771)
Ácido Fólico 5.77 ng/ml (3.89 - 20)

[tex]

Some of those tests I've had, some I don't even recognize. Here's the problem with vitamin tests — they're set up for normal people, and we're not normal. Consequently, we have no way to judge whether the results are correct, or not. I recall receiving vitamin B12 results at the upper limit of the normal range, or above, when I was so vitamin B12 deficient that I was having serious neurological symptoms.

Over half of us have MTHFR gene mutations of various types, which compromises our ability to absorb certain important vitamins, and prevents our bodies from being able to convert many vitamins into the active forms, so that our immune system can use them. Consequently, many vitamin tests will show certain vitamin test results to be normal, or above range, when our body is actually starving for the active form of vitamins, because we're unable to use the vitamins in our system.if we're in good health, excess vitamins and minerals will be eliminated in our urine. If were not in good health, it's probably because were deficient in certain vitamins or minerals. These days, I've found that I'm way ahead if I just take my vitamins, and don't worry about the medical tests that are supposed to accurately evaluate their levels, because I have too many MTHFR gene mutations for those ordinary tests to be of much value.

The only time I recall any vitamin or mineral supplements failing me, was about 10 years ago when I was taking a magnesium supplement that was supposed to be highly absorbable, when it wasn't. It was a private label product that was supposed to contain magnesium glycinate. A lawsuit against it proved that it contained 50% magnesium oxide, which basically cut the effective labeled dose in half. I switched to Doctors Best Magnesium Glycinate, and I've been fine ever since.

Our recommendations are based on vitamin and mineral types and amounts that seem to work best for most of us, based on many years of data in our archives. They are definitely not medical community recommendations, because the medical community is unable to successfully treat MC for the long-term. But here's how to resolve your apparent dilemma: we offer our advice freely, with no obligation to use it. If you don't feel comfortable with these recommendations, then simply disregard them. Why belabor the details? That just generates unnecessary stress, and none of us needs additional stress.

Tex