Vitamin D and zinc

[charlie fh]

Hi tex thanks for looking over them. still think ill go with thorne when i get some more dosh .
Sorry i have another question for you or gabes regarding B vits etc if you dont mind.
Do you think that good methyl B vits can help regulate motility after a period of time of taking them? im starting to think one of the main reasons i cant acheive the hyperthetical "perfect stool" is because i have slightly fast motility. Every time i have imodium i seem to have a much better , more firmed stool. I just had a thought that because motility is nerve related and the B's help the nerves it could be a missing part of the puzzle.

anyhow, all the best.

charlie

[tex]

Here's my opinion. Gabes may have a different opinion, of course, because I'm just guessing. The B vitamins primarily help to alleviate neurological symptoms. That said, they should certainly be capable of altering the functioning of our digestive system, because if we need folate (the active form of folic acid), then yes, they should help with our digestion and metabolism in general. Motility is controlled by the enteric nervous system, so from that viewpoint, the active forms of the B vitamins might help with the regulation of motility. So it should be worth a try.

A few members here have successfully regulated motility by taking small (10 mg) doses of amitriptyline. But if you consider trying that, don't take more than 10 or 15 mg of amitriptyline, because when you get up closer to the normal treatment dose (50 to 75 mg), amitriptyline become very, very addictive, and you will have a bigger problem than you have now.

Tex

[Gabes-Apg]

based on my limited understanding - methylation cycle and B vitamins are also key for the detox function and liver support.
this may mean for some people your body starts to clear toxins from the cells. this may be a 'factor' but not only reason for loose stools.

my suggestion is let go of the goal of perfect stool. I can have months with no symptoms but my poop slightly changes day to day.
so long as there is no urgency, no accidents, not going more than 2-3 times a day - I am happy.
My poop can can change due to work stress, or a change in routine.

[charlie fh]

Thankyou .
Tex, funny you should say that because i was on amitriptyline for year after my DR put me on them after i first developed MC symptoms. before my diagnosis. Its nasty stuff even on 10mg... it works at calming the nerves but it creeps up on you and i developed anxiety and nervous sensations so tapered off. which was also nasty.

anyhow thank you for the advice much apreciated . and Gabes thanks ..from what i can tell B1 seems to be the one that could help with vagus nerve function which may help molilty issues..
its really hard to find functional doctors this side of the pond. i would love to run my gene variations by someone who has a better understanding . Dunt suppose anyone knows anyone on here?

All the best!

[Gabes-Apg]

as I am in Australia I am not able to suggest practitioners to you

when I first learnt about methylation, and was reviewing my full methylation profile based on DNA results, I did quite a bit of reading on the Amy Yasko website and a few others and got information about each of the SNPS that are part of the methylation profile

from memory it was that research that I learnt about the Vitamin D receptor within the cell, and importance of magnesium for the body to use Vit D properly

https://www.livingwithmthfr.org/genetic ... genes/comt
if you can find chat groups/support groups and maybe ask participants for recommendations of practitioners in your area

I set up a methylation area of the forum back in 2015. not sure if any of the links still work but if you google the names and key words you will get correct links
viewtopic.php?t=21059

[charlie fh]

Hi Gabes thanks for this info ill check it out

I found this guy called Ben lynch who seems interesting . He wrote a book called dirty genes and has a load of videos on youtube. hes a bit deep though so scrambles my brain a bit.

This new approach to health gives me hope for the future. Most of my problems were cause by ignorant doctors who dished out antibiotics and PPI's that i didnt really need. My GP is still trying to stop me taking vitamin d for having raised levels.. its crazy. Anyhow sorry rant over.


cheers!

[charlie fh]

Hello tex and gabes! Just a quick question completly off topic regarding this vit d zinc page.

How often if at all do you have an odd bad day regarding your gut. Im talking very loose WD bad days. I know it can happen to anyone even with the healthiest gut in the world but its different for people with MC. I seem to have the odd bad day once or twice every 2 months . Ive had one today unfortunately and the worry instantly kicks in that im in a flare or something . Im starting to wonder maybe i just detox things sometimes in an extreme way..
I know a little hyperthetical question but just curious if you guys have similar days.

Hope your good

[tex]

For me, maybe about a dozen or so times per year, but I can almost always pin it to eating too much salt, because I eat a lot of tortilla chips and Fritos. Fritos are too salty, so if I overdo them, too much salt causes diarrhea. Other than that, the only problems I ever have occur maybe once every year or so, if I happen to catch a "stomach virus" of some kind that's going around.I don't recall having any idiopathic reactions in years. But I'm guessing that my situation is rather unusual among MC patients, because I got tired of reacting to cross-contaminated food, so I never, ever eat out, any more, and I eat a very limited diet.

Tex

[charlie fh]

HI tex thanks for that speedy reply. Good to know in a way we all have these bad days. you dont get worried or concern when these arise? i think i always worry or pani too instantly... when the next day things are usually fine. unless its a bug or something like you say. interesting you say about salt as ive increased my uptake a bit recently. sea salt that is. Ive also been a bit heavy on the fibre so suspect that. still trying to find the sweet spot.

If only life was simple ay!

[tex]

No, I don't worry, because once we learn how to control this disease, we can almost always figure out what we need to do, if we have a reaction — even if we have to go back to square one, because we can't figure out the specific cause of the problem, at the moment. And we're fortunate, because since were controlling our disease by diet, alone, we don't have to wait forever to get a doctors appointment, or seek help from anyone else — we already know what we need to do, to get back on track. And if we're not sure what to do, we can always ask here.

Tex

[Gabes-Apg]

my poop is semi normal 5 days out of 7

by the end of the working week (I get quite fatigued and there is a bit of stress with my job) I sleep more Friday night, sleep in a bit on a Saturday.
Then about 9am it is like all the tension leaves my body via messy poop. the stools are looser (almost MC mud) and I will go about 3 times within an hour.

Stress has always been one of my triggers, so I am not surprised.

on the days you have the looser stools, look at the previous 24 hours, is there anything different to other days?

[charlie fh]

Thank you. really good to know that a few bad days dont mean a full on flare is on the way and that you guys have them too. i know that sounds idiotic but i was more inclined to think that way.

I think stress is a big one for me also . I also think i still have a leaky gut which isnt helping matters. I get the odd random reaction to a food thats usually ok. Any tips on leaky gut... i havnt really tried bone broth. i read all these different things its hard to know where to start. apart from correct diet obviously.

MAny thanks !

[tex]

Here's a link to a Microscopic Colitis Foundation Newsletter that contain some information on bone broth, and it also contains Gabe's recipe for bone broth:

https://www.microscopiccolitisfoundatio ... h_2023.pdf

Tex

[jbrohlr]

The excess salt causing diarrhea is interesting. I'm in the category of having to take my Mg topically because even ingesting Mg glycinate causes watery stool. Could it be that if your gut is "sensitive" to Mg that even moderate amounts of salt (NaCl) can draw water into your large intestine? It would make sense since salt is hydrophilic like magnesium salts are.

For quite a while now I have been averaging 2 BMs a day (from 0 to 3, the median is probably 2 as well). My stools are either solid or watery (with some solids mixed in). I have not had anything in between (#5s, MC Mud, etc.) for a few months. I had some steatthoria for a couple of weeks in late May/early June but that has subsided.

The other question: can you draw water into and increase motility in the small intestine as well?

Leastways, I am going to cut down on salt and see what happens.

John R.

[tex]

To answer both questions, sodium is an electrolyte (so is magnesium), and all segments of intestine from duodenum to distal colon have mechanisms for both absorbing and secreting water and electrolytes. Diarrhea originates in the small intestine, when sodium and water is drawn into it. The colon is just an innocent bystander that gets caught up in the fun, so it infuses additional water and electrolytes, in order to do its part to assist the diarrhea/purging process.

Minimizing salt for a day or two should tell tell you if salt is the primary problem.

Tex