Dr. Fine's results for Cristi

cludwig · Post by **cludwig** » Wed May 24, 2006 12:54 pm

Hi everyone,

I finally got the results and wanted toshare them with you.

MY fecal antigliadin IgA was 70.5 making me gluten intolerent and cow,s milk was 52 so diary is out too.......I was borderline for egg, soy and yeast. The acute colitis test was negative and my absorption is normal.

I have two genes for gluten sensitivity...but none for celiac disease.

Now here's the one i don't understand......the fecal antitissue transglutannase IgAis elevated. I have no idea what this means. Could someone clear this up for me?

Thank you,

Cristi

Post by **tex** » Wed May 24, 2006 1:50 pm

Hi Cristi,

Ok, now you have something to work with. It looks as though you caught it in time, and started the diet before you developed significant damage to your small intestine. That's certainly good.

An elevated fecal antitissue transglutannase IgA value means that your immune reaction to gliadin has resulted in an autoimmune reaction to the human enzyme tissue transglutaminase. This is the antibody that is believed to be responsible for all the autoimmune diseases associated with gluten sensitivity, and it could be causing, (or at least contributing to), the other problems that you are currently having.

Thanks for sharing this information. If you don't mind posting your specific gene test results, I'd be happy to add them to the thread on that topic.

Tex

Tessa · Post by **Tessa** » Wed May 24, 2006 1:58 pm

Thanks for sharing your results, Cludwig.
Now you have something to start with.

I am glad you now what´s going on and are able to start an appropriated diet.

Take care,
Love,
Tessa

cludwig · Post by **cludwig** » Wed May 24, 2006 4:46 pm

Hi,

So these are my specific gene test results.....which I don't understand except for the brief expaination on the lab report.

HLA-DQB1 molecular analysis allele 1 0301

HLA-DQB1 molecular analysis allele 2 0501

Serologic equivalent HLA-DQ 3, 1 ( subtype 7, 5 )

Any insights into the meaning of these would be wonderful.

Thanks so much

Cristi

thedell19 · Post by **thedell19** » Wed May 24, 2006 6:49 pm

My test results are almost identical to yours. The only difference is that you said you were borderline for eggs, yeast, and soy. I am not intolerant of egg yeast or soy (as shown by the tests). But at least you know what you need to do. I also caught it before there was any damage to my intestines and absorbtion.

When are you starting your diet? I am 8 days into mine. Tough so far because I really want some italian bread.

cludwig · Post by **cludwig** » Wed May 24, 2006 8:43 pm

Hi Thedell19,

I actually started a diet 4 months ago....unfortunately my blood work and small bowel biopsy were neg for glutin....so i was eating oatmeal twice a day. Then two months ago I added cheese quesideas(sp?) and got really sick. So i was confused until I stumbled on Dr. Fine's stuff online.

So to answer your question, I think I got all the gluten out about a month ago, although I was using a spice up until last week that I'm not sure about so I don't use that anymore. I've just started feeling better this week, but my husband said I was showing signs of getting better the week before. My stamina is better and the aches and weakness in my shoulders and arms is much better. The nausia finally let up this week and the gas pressure is improving as well.

As far as the D goes...I'm still having some....but not as loose and the quantity is getting less. Also I'm just not as sick as i was two weeks ago when i was having the episodes. It's just been baby steps but it's all going in the right direction.

I was also on entocort for 8 weeks but unfortunately I wasn't off the gluten because I wasn,t aware of the link. The entocort definitely helped the D when I was on it but not with the flu like symptoms that I was feeling. And then I went on to consume gluten so I unknowingly messed my system up again.

Now I'm dealing a lot with stress, because I've been so sick for so long(6 mos.) and because stress hormones have been affected because of the autoimmune responce to the gluten.

Sorry, this has gotten long, but even with still having symptoms...I'm feeling better than I have in 6 mos. I'm sure hoping to get even better and I'm sure it's due to getting the gluten out of my diet....this is all more than a coincidence.

As far as diet goes..I had gotten away from eating meat .....but thats what I've resorted to eating a lot of...and kind of enjoying it. I can share what else I've been eating if you want.

Best of luck,
Cristi

Post by **tex** » Wed May 24, 2006 10:13 pm

Cristi,

I added your gene test results to the "Genes" thread in the "Polls" forum.

As far as what they actually mean--I'm not sure that anyone really knows what they actually mean. Basically, all we know is that the two that you have, predispose you to gluten sensitivity, and microscopic colitis, but neither one of them is one of the known celiac genes.

Thanks for sharing your results

Tex

moremuscle · Post by **moremuscle** » Sun May 28, 2006 8:57 pm

I am so delighted to read that you are feeling a little better than you have been for 6 months. There is nothing quite like this disease - it is VERY difficult to live with and I think all of us here can relate to the feeling of being close to completely loosing it.

Your test results are tough to deal with too because of the massive amount of intolerances you are facing. It is a BIG mouthful for sure. The only positive is KNOWING it - that's it; it's a smack in your face but at least you kind of know what you have to deal with. Gluten and Casein (dairy) is bar far the most common intolerances for us with MC.

You are SO brave to take on this diet project - but you will thank yourself when you slowly but surely get a grip and start to see and feel the results. And you WILL get a grip - it is easier than you imagine. Have you read about the Paleolithic Diet yet? It may inspire you.

Love,
Karen

cludwig · Post by **cludwig** » Sun May 28, 2006 10:05 pm

Hi Karen,

I really don't know much about the Paleolithis Diet. I think it eliminates all grains though. The only grain I'm eating now is rice. I'm eating lots of chicken and cod , fruits and veggies , and cashew butter. ...also olive oil and flaxseed oil. If you have a good book on the subject I'd love to learn more.

BTY, I hear you run marathons. I am so impressed. It gives me such inspiration to know someone with MC has been able to accomplish such a physically demanding race. Very cool.

Thaanks, Cristi

Polly · Post by **Polly** » Mon May 29, 2006 7:58 am

Hi Cristi!

The paleo "bible" is by Loren Cordain, PhD, and is titled "The Paleo Diet". It is excellent and very well researched/scientific. Another book on the topic is called "Neanderthin" by Ray Audette.

I also found another book helpful - "The Allergy Self-Help Cookbook" by Marjorie Hurt Jones, R.N.

You will be able to be physically active again, so don't despair. Although I have never run a half-marathon like Karen did recently (isn't she AMAZING???), I do run 3 miles 4 or 5 times a week and also lift some light weights. So there IS hope!

Love,

Polly

cludwig · Post by **cludwig** » Mon May 29, 2006 10:08 am

Hi Polly,

Thanks....I will definitely look at these...the more informed the better. I'm so glad you've healed to the point where you can exercise that much. It seems unimaginable to me at this point....just cooking and cleaning up leaves me tired. It's a lot easier to keep at this diet when I hear how well you are doing.

Thanks,
Cristi