"Why Most Published Research Findings Are False"

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tex
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"Why Most Published Research Findings Are False"

Post by tex »

That's the name of a very scholarly, (and very depressing), article by Dr. John Ioannidis, an epidemiologist who studies research methods at the University of Ioannina School of Medicine in Greece, and Tufts University in Medford, Massachusetts. The article is very analytical and quite detailed, and convincingly argues his point - namely, that "There is an increasing concern that in modern research, false findings may be the majority or even the vast majority of published research claims." (The red emphasis is mine).

Dr. Ioannidis bluntly states that "A new claim about a research finding is more likely to be false than true." (Again, my emphasis). If that doesn't shake your faith in modern medical research, you're a lot more trusting of the medical research industry than I am.

For example, Dr. Ioannidis and his colleagues analyzed 432 published research claims that were based on gender and genes. Close examination revealed that almost none of them were valid. In fact, only one of them was replicated. Is that incredible, or what? You can read his entire article at PLoS Medicine, which is a peer-reviewed, open-access journal, published by the Public Library of Science.

http://medicine.plosjournals.org/perlse ... ed.0020124

This article was published on August 30, 2005, so apparently it has successfully met the test of peer review, and can be considered to be generally valid.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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MaggieRedwings
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Post by MaggieRedwings »

Hi Tex,

Why does that not surprise me! I am sure you and I just might be equal on the trust in them issue.


My faith in the medical community has steadily gone down hill but am very happy that both my GP & Gastro docs are living in the real world.

This experience with the top rated Ear doc in our area has left me with the very definite impression that I was wheeled through a medical meat market. All of the energy was from me and all of the follow-up. Hate to sound bitter but that is the way it is.

Love, Maggie
Maggie Scarpone
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tex
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Post by tex »

I certainly can't argue with your observations. After all that you went through, the least they could have done would have been to inform you of the results, as soon as they had them. After all, they are the ones making the big bucks out of your test - it's not like they were doing you a favor by providing you with free testing.

"Medical meat market", (sad to say), is probably a pretty accurate description of the routine, in cases such as this.

Love,
Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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