More on Naltrexone

[mle_ii]

Ok how about this for strange. I recently brought up some information about taking a low dose naltrexone.

http://www.perskyfarms.com/phpBB2/viewt ... xone#44334

So I search here for the post that I recently wrote here and what else do I find?

http://www.perskyfarms.com/phpBB2/viewt ... xone#36967

Seems I tripped over but didn't pay any attention to it at the time.

Oh and here's why I was searching for the post. I wanted to reply with a response to a recent article that was talking about the relationship of food allergies (wheat and dairy specfically) with mercury.

Thanks for sharing this information Bernard. I found this article the most interesting:
http://www.flcv.com/autismgc.html

I found it interesting as I think that this has a tie in with Microscopic Colitis. I think that the mercury amalgams and other environmental/biological factors played a part in the manifestation of this disease in me. What I find even more curious is the mention
of naltrexone (sp). I had recently been told about taking a low dose naltrexone by an internal medicine Dr to help out with my GI issues. I just started taking it so I can't say much thus far. But I have also been chelating starting in January and noticed some improvement; this after having 11 amalgams for most of my almost 39 yo life recently removed.

Some things that I currently see as being suspect in Microscopic Colitis involve gut dysbiosis (mainly bacterial), somehow related to liver bile issues, motility issues and acid production. That along with intollerance of some sort to proteins in certain foods, mostly
gluten, dairy proteins, and possibly soy proteins. Microscopic Colitis demonstrates a TH1 mucosal cytokine profile. It's amazing that your article seems to put all of these into the perspective of mercury or other heavy metals being a part of the cause.

Thanks,
Mike

More wondering to do for sure. :)

Thanks,
Mike

[mle_ii]

I recently found a person in another group who says that their Lymphocytic Colitis wasn't helped by any drugs. But they started taking Naltrexone to help with something else which ended up helping her colitis.

I'm going to find out more information and perhaps get them to write their comments here.

Thanks,
Mike

[mle_ii]

For those interested hear's the thread thus far:
http://health.groups.yahoo.com/group/lo ... sage/62372

Though you'll need to be a member of the group to see it.

To summarize. She's had D for years, started taking LDN since March 1 and if she doesn't eat rich food she doesn't have D. She used to have to take Lotomil every day.

It sure would be interesting to see if this helps out anyone else who's having symptoms with it right now. I'm not sure I count as result since mine was very mild and the last colonoscopy showed no inflamation.

Thanks,
Mike

[tex]

Mike,

In that first "old" topic that you cited in your first post above, you said":

I remember some questions as to why smoking plays a role, I wonder if it's somehow related to why they think that low dose naltrexone can help folks with Crohn's Disease and some other autoimmune diseases.

You may have already seen this before, but "they" don't just "think" that LDN will help people with Crohn's disease. In the trial described in the link below, for example, eighty-nine percent of patients exhibited a response to LDN therapy and 67% achieved remission, (note that they used LDN concurrently with any prior treatment that they were already taking, (except that they withdrew all Remicade, (infliximab), eight weeks prior to the trial):

http://www.ncbi.nlm.nih.gov/pubmed/17222320

Since the most serious side effect of LDN that was noted during that particular trial was sleep disturbances, (which many/most of us have anyway, as a result of MC), I'm frankly kind of surprised that no one in the medical profession seems interested in recommending LDN for treatment of MC and UC. Of course, the article that I cited is less than a year old, so perhaps a few doctors will eventually notice it and try LDN with a few of their patients.

In cases where where remission is elusive, perhaps LDN should be added to treatment regimens that use "conventional" medications for IBDs, rather than trying to use it as a separate and sole treatment. It would appear to be safer to use LDN combined with one of the 5-ASA meds, or budesonide, for example, than to use meds such as prednisolone and methotrexate. Or am I overlooking something?

Incidentally, just out of curiosity, does "rich food" include bread, pizza, cakes, cookies, pies, etc. - IOW goods that contain gluten? LOL.

Tex

[mle_ii]

Yes, brain fart. Studies have indeed shown a good result with LDN with Crohn's Disease. And given it's similarities with MC I'm thinking it just might help.

I'll comment more when I get some more time. I gotta go home. :)