Update on Imuran

Discussions on the details of treatment programs using either diet, medications, or a combination of the two, can take place here.

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Pat
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Update on Imuran

Post by Pat »

My doctor's assistant called today and said that my recent test to check if the Imuran (Azathioprine) was at a therapeutic dose for me said that it was not. So they are upping my dose from 50mg to 100 mg. From what I have read they try to get you to 1mg per lb of body weight. Since I am only at 102.5 lbs I guess 100mg will be about there. (I'd like to gain a few more lbs) Hopefully it will help with the D. I am better on 50mg and 9mg of Entocort (and 2 Lomotil) but nowhere near normal. I think when I am better he will wean me off the Entocort. It apparently isn't doing the job for me.

Pat
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tex
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Post by tex »

Pat,

I don't recall how long you've been using the Entocort, but I have to agree, it seems like a long enough time for it to work, if it were going to.

Good luck with the 100 mg dosage rate of Imuran.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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mini
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Post by mini »

Hi Pat

Wow sorry to read you are still having problems with the D regardless of the Entocort, I really don't know what to suggest. The Aza normally takes around 2-3 months to really have an affect on the body hopefully soon you will get some kind of remission.

Take care and sending you :flowersmiley:
Pat
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Post by Pat »

Tex and Mini,

Thanks for your words of encouragement!

I've been on the Entocort for 2 weeks and the Imuran 5 weeks. I feel like such a freak sometimes. I just knew the Prednisone would work but it didn't and also made me feel bad. I just want something to work.

Thanks again,
Pat
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Gloria
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Post by Gloria »

Sorry to hear this, Pat. Two weeks isn't that long for the Entocort; I think it took 3-4 weeks for me to see a difference. I hope this combo will eventually work for you.

Gloria
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Post by ErinD »

sorry to hear you aren't finding much relief with the Entocort/Imuran. I hope the increase in the dose will help. I agree the two weeks of Entocort is still short to decide yet, my doc said it takes a good 3-4 weeks to see the true difference so maybe between the two you will be better soon!
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Post by Dee »

I agree in reference to the Entocort taking longer than 2 weeks to show an improvement.
I know it's easier said than done, but don't give up hope...
I'm sending (((((((Norman Vibes))))))))) your way..

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mini
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Post by mini »

If it helps although after taking the predisone, the Entocort worked on the D from day 2 it has taken me a good 6 weeks to feel the full benefit of the med. I shall be keeping my fingers crossed for you this time in time I am sure they will find something that works for you x
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tex
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Post by tex »

Pat,

I have to agree with what everyone else is saying. For some reason or other, I was thinking that you had been taking Entocort for a couple of months. It seems logical to assume that it might not provide relief where Prednisone had failed, but that certainly isn't chiseled in stone. If you're able to achieve remission now, it will be impossible to say whether it was due to the Entocort, the Imuran, or the combination, but I suppose you'll be so glad to see relief that it probably won't matter to you.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Pat
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Post by Pat »

Tex,

Yeah, I asked the doctor how he was going to know which was helping and all he said was, "That's a good question". I think he assumes that since the Pred did not help (only a little) that the Entocort wasn't really going to help either. I think he is just using it ( because it helps some ) to help me until the Imuran really kicks in and to see if I will have side effects to the Imuran. I took Prednisone from Jan 25 until Mar 19. The last week was only 10 mg and the Entocort on top of it. I really thought the Pred would help and certainly hoped the Entocort would help since I am on the diet. I took Entocort Jan 07 but was not on the diet. I guess time will tell.

Thanks to all for your support!

Pat
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