THought I'd post in case anyone is interested. As suspected, I am gluten, soy, & dairy intolerant. Now I feel I need to test yeast & egg, too. May as well! I don't fully understand the whole HLA genetic test bit, but I'll keep looking into that. It seemed significant that I have 2 copies of the gluten sensitive gene...and that my kids & siblings are a bit more likely to have these same issues than if maybe I'd had only one copy??
I'll keep avoiding gluten, dairy, soy, & corn as usual...
A) Gluten Sensitivity Stool and Gene Panel Complete *Best test/best value
Fecal Antigliadin IgA 15 (Normal Range <10 Units)
Fecal Antitissue Transglutaminase IgA 12 Units (Normal Range <10 Units)
Quantitative Microscopic Fecal Fat Score <300 Units (Normal Range <300 Units)
Fecal anti-casein (cow's milk) IgA antibody 11 Units (Normal Range <10 Units)
HLA-DQB1 Molecular analysis, Allele 1 0502
HLA-DQB1 Molecular analysis, Allele 2 0602
Serologic equivalent: HLA-DQ 1,1 (Subtype 5,6)
Soy Sensitivity Stool Test
Fecal Anti-Soy IgA 17 Units (Normal Range <10 Units)
Interpretation of Fecal Antigliadin IgA: Intestinal antigliadin IgA antibody was elevated, indicating that you have active dietary gluten sensitivity. For optimal health, resolution of symptoms (if you have them), and prevention of small intestinal damage and malnutrition, osteoporosis, and damage to other tissues (like nerves, brain, joints, muscles, thyroid, pancreas, other glands, skin, liver, spleen, among others), it is recommended that you follow a strict and permanent gluten free diet. As gluten sensitivity is a genetic syndrome, you may want to have your relatives screened as well.
Interpretation of Fecal Antitissue Transglutaminase IgA: You have an autoimmune reaction to the human enzyme tissue transglutaminase, secondary to dietary gluten sensitivity.
Interpretation of Quantitative Microscopic Fecal Fat Score: Provided that dietary fat is being ingested, a fecal fat score less than 300 indicates there is no malabsorbed dietary fat in stool indicating that digestion and absorption of nutrients is currently normal.
Interpretation of Fecal anti-casein (cow's milk) IgA antibody: Levels of fecal IgA antibody to a food antigen greater than or equal to 10 are indicative of an immune reaction, and hence immunologic "sensitivity" to that food. For any elevated fecal antibody level, it is recommended to remove that food from your diet. Values less than 10 indicate there currently is minimal or no reaction to that food and hence, no direct evidence of food sensitivity to that specific food. However, because 1 in 500 people cannot make IgA at all, and rarely, some people can still have clinically significant reactions to a food antigen despite the lack of a significant antibody reaction (because the reactions primarily involve T cells), if you have an immune syndrome or symptoms associated with food sensitivity, it is recommended that you try a strict removal of suspect foods from your diet for up to 12 months despite a negative test.
Interpretation Of HLA-DQ Testing: Although you do not possess the main HLA-DQB1 genes predisposing to celiac sprue (HLA-DQB1*0201 or HLA-DQB1*0302), HLA gene analysis reveals that you have two copies of a gene that predisposes to gluten sensitivity (any DQ1, DQ2 not by HLA-DQB1*0201, or DQ3 not by HLA-DQB1*0302). Having two copies of a gluten sensitive gene means that each of your parents and all of your children (if you have them) will possess at least one copy of the gene. Two copies also means there is an even stronger predisposition to gluten sensitivity than having one gene and the resultant immunologic gluten sensitivity may be more severe.
Interpretation of Fecal Anti-Soy IgA: Levels of fecal IgA antibody to a food antigen greater than or equal to 10 are indicative of an immune reaction, and hence immunologic "sensitivity" to that food. For any elevated fecal antibody level, it is recommended to remove that food from your diet. Values less than 10 indicate there currently is minimal or no reaction to that food and hence, no direct evidence of food sensitivity to that specific food. However, because 1 in 500 people cannot make IgA at all, and rarely, some people can still have clinically significant reactions to a food antigen despite the lack of a significant antibody reaction (because the reactions primarily involve T cells), if you have an immune syndrome or symptoms associated with food sensitivity, it is recommended that you try a strict removal of suspect foods from your diet for up to 12 months despite a negative test.
My Enterolab Results
Moderators: Rosie, Stanz, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh
My Enterolab Results
Kimberley
MC diagnosed 2004
Suspected Eosinophilic Gastroenteritis...??
Meds/Supplements: Probiotics, Prenatal Vitamins, Vitamin D3.
MC diagnosed 2004
Suspected Eosinophilic Gastroenteritis...??
Meds/Supplements: Probiotics, Prenatal Vitamins, Vitamin D3.
Hi Kimberley,
Yes, we are interested. Thanks for posting that information. We learn a lot by comparing each others genes, intolerances, and reactions.
You are now officially a member of what we refer to as the Double DQ 1 club - other members here include Polly, Gloria, Celia, and Carrie's DH Rick. I'm probably forgetting someone, but right now my mind draws a blank on other members. You obviously inherited a gluten-sensitive gene from each parent. MCers with Double DQ 1 genes always seem to have many intolerances, and they are very sensitive to their intolerances, and they usually take longer to achieve remission, (probably due to the extra time needed to discover all the food intolerances, and the extra healing time required, due to their heightened sensitivities). You can probably get a pretty good idea of the extent of your intolerances, by looking at the list that Polly has posted beneath her avatar in all her posts.
Do you mind if I add your gene test results to our collection of HLA-DQ Gene Molecular test results in this forum?
http://www.perskyfarms.com/phpBB2/viewtopic.php?t=2645
Thanks,
Tex
Yes, we are interested. Thanks for posting that information. We learn a lot by comparing each others genes, intolerances, and reactions.
You are now officially a member of what we refer to as the Double DQ 1 club - other members here include Polly, Gloria, Celia, and Carrie's DH Rick. I'm probably forgetting someone, but right now my mind draws a blank on other members. You obviously inherited a gluten-sensitive gene from each parent. MCers with Double DQ 1 genes always seem to have many intolerances, and they are very sensitive to their intolerances, and they usually take longer to achieve remission, (probably due to the extra time needed to discover all the food intolerances, and the extra healing time required, due to their heightened sensitivities). You can probably get a pretty good idea of the extent of your intolerances, by looking at the list that Polly has posted beneath her avatar in all her posts.
Do you mind if I add your gene test results to our collection of HLA-DQ Gene Molecular test results in this forum?
http://www.perskyfarms.com/phpBB2/viewtopic.php?t=2645
Thanks,
Tex
Yes, that definitely ups the odds, for all of them. Remember, though, that having a gene does not guarantee that any disease connected with the gene will become a reality. Certain other conditions have to be met before the disease will be "triggered".
Thanks, I'll go add that information.
Tex
Thanks, I'll go add that information.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.