Absorption of SSRIs & other drugs

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Darby
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Joined: Tue May 04, 2010 1:15 pm

Absorption of SSRIs & other drugs

Post by Darby »

My apologies if this has been discussed (I'm a newby). Has anyone here had this problem? I've been taking a very low dose of Effexor XR (37.5mg) for about 12 years and it has worked fine for me. However, several months ago I started feeling like I hadn't taken it. I'd wake up in the middle of the night with that kind of strobe light in the brain feeling. I called the prescribing doc who said that some people start having it pass through their liver more quickly so he told me to double the dose. (I mentioned my GI problems to him which are as of yet still undiagnosed but sound like I belong here). I've felt fine for the last six weeks but now I'm having the same problem again -- waking up at night and feeling like I haven't taken the med. By the way, Effexor XR has a very short half life and if you skip a dose the symptoms are not much fun. Has this happened to anyone else here? I have an appt with my GI doc in a week so I'll tell him but my prescribing doc just scratched his head and told me to find another doc in my new city. Is this a malabsorption problem?
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tex
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Post by tex »

Darby wrote:Is this a malabsorption problem?
Probably. The bad news is that SSRIs have been shown to be associated with causing MC, including Effexor, (venlafaxine):

http://www.ncbi.nlm.nih.gov/pubmed/18502544

Since you are experiencing suspicious GI symptoms, also, the most likely scenario is that you may be developing either celiac disease or MC, either one of which can cause a malabsorption problem.

Also, please be aware that SSRIs are associated with a loss of mineral density, (IOW, osteoporosis) of the hip bones.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Darby
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Joined: Tue May 04, 2010 1:15 pm

Post by Darby »

Thanks so much, Tex. I really did not know this. I'm off to do more research. I've gotten myself off Advil so I guess I can do Effexor too although I'm sure it will be no picnic.
--Darby
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tex
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Post by tex »

You're very welcome.

Please keep us updated.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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