Questran?

Discussions on the details of treatment programs using either diet, medications, or a combination of the two, can take place here.

Moderators: Rosie, Jean, CAMary, moremuscle, JFR, Dee, xet, Peggy, Matthew, Gabes-Apg, grannyh, Gloria, Mars, starfire, Polly, Joefnh

Post Reply
IDreamInColor
Adélie Penguin
Adélie Penguin
Posts: 167
Joined: Tue Sep 14, 2010 5:20 pm
Location: Ohio

Questran?

Post by IDreamInColor »

So the doc prescribed questran to treat the MC, has anyone had any experience with this medication? It's in powder form that I am suppose to mix with water twice a day.
Thanks for all the input :)
User avatar
tex
Site Admin
Site Admin
Posts: 35068
Joined: Tue May 24, 2005 9:00 am
Location: Central Texas

Post by tex »

Questran is a bile acid sequestrant. For some individuals, it tends to temporarily slow down diarrhea, but it does nothing to address the source of the inflammation which causes MC. Questran is often used to treat IBS, but it is only a band-aid, when used for an inflammatory bowel disease. It treats a symptom, not the disease.

That said, some other members use it, for temporary relief from diarrhea, but you really need a way to reduce the inflammation, also, if you are ever going to get the disease under control.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
IDreamInColor
Adélie Penguin
Adélie Penguin
Posts: 167
Joined: Tue Sep 14, 2010 5:20 pm
Location: Ohio

Post by IDreamInColor »

Thank you for that info. Having just been diagnosed today, I am clueless. How do you get the inflammation under control? My doctor talked as if the questran was the treatment for it. Are their better ways of dealing with this?
JLH
King Penguin
King Penguin
Posts: 4282
Joined: Tue Jun 17, 2008 9:34 pm

Post by JLH »

:welcome: Boy, you are really fast in finding us. Good for you. This is the best place in the world for information and support. Most docs, GIs or otherwise, do not have the experience that we do. Strange but true.

Read as much as you can here starting with the newbies section. Also, check out www.enterolab.com
DISCLAIMER: I am not a doctor and don't play one on TV.

LDN July 18, 2014

Joan
JLH
King Penguin
King Penguin
Posts: 4282
Joined: Tue Jun 17, 2008 9:34 pm

Post by JLH »

I forgot to say that I am a transplanted Buckeye.
DISCLAIMER: I am not a doctor and don't play one on TV.

LDN July 18, 2014

Joan
User avatar
Gabes-Apg
Emperor Penguin
Emperor Penguin
Posts: 8332
Joined: Mon Dec 21, 2009 3:12 pm
Location: Hunter Valley NSW Australia

Post by Gabes-Apg »

Hi there from Australia- welcome to the group


My GI specialist prescribed questran for me

at first he prescribed 8grams twice a day, when i got the script filled the pharmacist raised concerns about dosage, timings in relation to my other medications i was taking it was impossible to juggle that schedule with eating, sleeping and taking medications (you can not have other medications 4 hours before or 6 hours after having the questran)

i started with 8 grams 4 hours after the evening meal, over the period of 3 - 4 months i reduced this to 'as required'

as Tex said, this doesnt reduce inflammation it just slows down the process so there is more time for the body to absorb water

if i am having D symptoms i use questran instead of loperamide or lomotil, as it slows down the process rather than stopping it totally.


The GI specialist did prescribe an anti-inflammtory (Dipentum) - i found that this gave me chronic headaches and when i was researching the side effects one of the top 3 was diarrhea!! i only took this for about 3 weeks before i stopped it. the D was alot less once i did stop this medication


I use natural supplements and foods to help reduce the inflammation

boiling rice in extra water and not straining it/rincing it so having 'gooey rice' is very good as this liquid is a natural anti-inflammatory
i also used alot of natural gelatin as this is good for leaky gut etc

hope this helps
Gabes Ryan

"Anything that contradicts experience and logic should be abandoned"
Dalai Lama
User avatar
tex
Site Admin
Site Admin
Posts: 35068
Joined: Tue May 24, 2005 9:00 am
Location: Central Texas

Post by tex »

The inflammation is usually due to food sensitivities, but certain drugs can also cause MC, these include, but are not limited to, NSAIDs, PPIs, SSRIs, antibiotics, etc. For some people, just stopping the use of the drug that is causing the problem can bring remission, without further intervention. For the rest of us, we either have to use a drug such as mesalamine, or Entocort EC, or we have to modify our diet, in order to eliminate all traces of the foods that we are sensitive to, (usually gluten, all dairy products, and for about half of us, soy). Some of us have additional sensitivities, though, such as eggs, yeast, corn, carrageenan, etc. We are all different, and part of the difference, of course, is genetic.

The most effective medication available for treating MC is Entocort EC, while the safest treatment is the diet, of course. We all have to figure out our own treatment program, depending on our sensitivities, and our lifestyle. Be aware that most GI docs will argue that diet has nothing to do with MC, (because that's what they are taught in med school), but many members of this discussion board have had very good success controlling their symptoms that way.

Tex
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
User avatar
hoosier1
Rockhopper Penguin
Rockhopper Penguin
Posts: 764
Joined: Mon Sep 06, 2010 6:09 am
Location: Indiana

Post by hoosier1 »

I found that I had to cut the normal dosage of Questran in half or else it really bound me up. Also, you need to take really good care of your teeth when on Questran, i.e. brush immediately after drinking it because it is very aggressive to the enamel.

I found I had better luck with Colestid which is a pill form of Questran. Be sure to drink lots of water with either form because you don't want either lodging in your GI. Colestid, since it is a pill, does not harm your teeth and it is so much easier to carry when you are in a pinch.

But I agree with my friends on this board, it does nothing to reduce the inflammation. It does have a nice side effect. It lowers your cholesterol, if that is a problem for you.

Good luck with it but I would keep the dosage low for a while.
Post Reply

Return to “Discussions on Treatment Options Using Diet, and/or Medications”