I've seen several references (here and other places) to an article written by Dr. Fine about Prevacid possibly causing MC. I searched and searched last night, but could find nothing about it.
Does anyone have a link to this documentation that I might take to my doctor. I don't want to take Prevacid anymore, but to get my insurance company to cover Protonix, I will need to file a waiver with my medical records, a letter from my doctor.
Thanks,
Lisa
Prevacid
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Hi, again, Lisa,
Polly is probably the person that will know about this. She is a pediatrician and may have gone in to work. We will hear from her before too long, however. She never lets a day (or an hour) go by without checking in here!!
Lots of love,
Sally
Polly is probably the person that will know about this. She is a pediatrician and may have gone in to work. We will hear from her before too long, however. She never lets a day (or an hour) go by without checking in here!!
Lots of love,
Sally
Mitakuye oyasin
(Lakota for "We are all related")
(Lakota for "We are all related")
I can't find Dr. Fine's article either - dang it! - but thought you might find these articles worth a read.
http://www.hhmi.org/news/merchant.html
http://www.selfgrowth.com/articles/Shipko1.html
Peggy
http://www.hhmi.org/news/merchant.html
http://www.selfgrowth.com/articles/Shipko1.html
Peggy
Hi Lisa,
I've been looking for the article you mentioned, but so far I've been unsuccessful. However, I have found a valid reference in the Journal of Clinical Gastroenterology. Though the article is about CC, the symptoms, causes, and treatment of CC, LC, and MC are all the same:
http://tinyurl.com/7dema
As I'm sure you are aware, Prevacid is a tradmarked brand of Lansoprazole. Unfortunately, a subscription is required to access the full text of the article, as is the case with many of the better trade publications. Perhaps your GI has a subscriptiopn, and can access it, if he needs more details.
Incidentally, the reason why the PPIs are a risk factor for colitis, is because of what they do so well, namely lowering stomach acidity. Stomach acid is effective in controling infectious organisms, and preventing them from continuing on through the digestive system. The quote below is from this site:
http://www.emedmag.com/html/pre/gic/consults/011505.asp
"In addition, proton pump inhibitors appear to increase the risk of acquiring CDC by reducing the acid concentration in the stomach and allowing the organism to pass unharmed into the intestine. Patient-to-patient transmission increases the risk of acquiring CDC. Patients with an infected roommate are more likely to get CDC than patients without an infected roommate. Transmission of infection by hospital personnel contaminated with C. difficile is possible but preventable by using disposable gloves and washing hands thoroughly after examining patients."
This is along the same line of thought as the first reference that Peggy cited. C. Difficile is another risk factor for MC, that is to say, a C. Diff infection can result in MC.
It follows that if the PPIs can contribute to the risk of acquiring C. Diff, they probably also contribute to the development of other forms of colitis.
I'll keep searching for other references.
Wayne
P S Sorry that my post requires horizontal scrolling, the link to that first reference is ridiculously long.
P P S Note that the first reference also suggests that your symptoms may resolve, after discontinuing the use of Prevacid. Let's hope that you are one of the lucky ones.
I've been looking for the article you mentioned, but so far I've been unsuccessful. However, I have found a valid reference in the Journal of Clinical Gastroenterology. Though the article is about CC, the symptoms, causes, and treatment of CC, LC, and MC are all the same:
http://tinyurl.com/7dema
As I'm sure you are aware, Prevacid is a tradmarked brand of Lansoprazole. Unfortunately, a subscription is required to access the full text of the article, as is the case with many of the better trade publications. Perhaps your GI has a subscriptiopn, and can access it, if he needs more details.
Incidentally, the reason why the PPIs are a risk factor for colitis, is because of what they do so well, namely lowering stomach acidity. Stomach acid is effective in controling infectious organisms, and preventing them from continuing on through the digestive system. The quote below is from this site:
http://www.emedmag.com/html/pre/gic/consults/011505.asp
"In addition, proton pump inhibitors appear to increase the risk of acquiring CDC by reducing the acid concentration in the stomach and allowing the organism to pass unharmed into the intestine. Patient-to-patient transmission increases the risk of acquiring CDC. Patients with an infected roommate are more likely to get CDC than patients without an infected roommate. Transmission of infection by hospital personnel contaminated with C. difficile is possible but preventable by using disposable gloves and washing hands thoroughly after examining patients."
This is along the same line of thought as the first reference that Peggy cited. C. Difficile is another risk factor for MC, that is to say, a C. Diff infection can result in MC.
It follows that if the PPIs can contribute to the risk of acquiring C. Diff, they probably also contribute to the development of other forms of colitis.
I'll keep searching for other references.
Wayne
P S Sorry that my post requires horizontal scrolling, the link to that first reference is ridiculously long.
P P S Note that the first reference also suggests that your symptoms may resolve, after discontinuing the use of Prevacid. Let's hope that you are one of the lucky ones.
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Lisa,
Here's a better reference:
http://tinyurl.com/9k77n
Or, if you prefer, here's the same information from another source, The American Journal of Gastroenterology:
http://tinyurl.com/cn3q2
I hope this helps:
Wayne
Here's a better reference:
http://tinyurl.com/9k77n
Or, if you prefer, here's the same information from another source, The American Journal of Gastroenterology:
http://tinyurl.com/cn3q2
I hope this helps:
Wayne
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Wayne! It does! Thank you. I'm going to print these out and send them to my doctor.tex wrote:Lisa,
Here's a better reference:
Or, if you prefer, here's the same information from another source, The American Journal of Gastroenterology:
I hope this helps:
Wayne
I will also send him the link to the subscription site and ask him to write me a letter for waiver.
<B>Thank you!</B>
BTW. If ever you want to link to something really long, without horizontal scrolling, you can go to one of these two places:
http://snurl.com/
http://tinyurl.com/
All you do is cut and paste the long URL into the space provided, and it will create a short one for you.
For instance: Here's the American Journal of Gastro link:
http://tinyurl.com/cn3q2
Thanks again. This is a <I>huge</I> help.
Lisa
Lisa,
You're very welcome.
Wow! That link shortening site works like a charm. I was totally unaware of that nifty trick. I added a link to my "Links" toolbar. Now all I have to do is click on that link, and the URL of the site being displayed on the monitor, is automatically shortened. That's about the niftiest thing since sliced bread.
Many thanks,
Wayne
You're very welcome.
Wow! That link shortening site works like a charm. I was totally unaware of that nifty trick. I added a link to my "Links" toolbar. Now all I have to do is click on that link, and the URL of the site being displayed on the monitor, is automatically shortened. That's about the niftiest thing since sliced bread.
Many thanks,
Wayne
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Sally,
I'll bet your browser contains a "Personal Toolbar Folder". If it does, by clicking on the tiny arrow at the lower left corner of your toolbar area at the top of your browser, you can open a "Link" Toolbar, where links in that Personal Toolbar Folder will be displayed for instant access. It's very handy for tools such as this URL "shortener".
Love,
Wayne
I'll bet your browser contains a "Personal Toolbar Folder". If it does, by clicking on the tiny arrow at the lower left corner of your toolbar area at the top of your browser, you can open a "Link" Toolbar, where links in that Personal Toolbar Folder will be displayed for instant access. It's very handy for tools such as this URL "shortener".
Love,
Wayne
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.