Observation

Discussions can be posted here about mediator release testing (MRT), as offered by Oxford Biological Technologies, in conjunction with the LEAP program, which is claimed to determine a relative level of sensitivity to various foods and chemicals by measuring an increase in the ratio of liquids to solids in a blood sample that has been exposed to a specific allergen.

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Polly
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Observation

Post by Polly »

Have you noticed that the first 4 of us to post MRT results (Mary Beth, Gloria, Kari, and I) all have the double DQ genetic pattern? Kari has double DQ 2, the rest of us double DQ1. Double DQ genes definitely are associated with multiple food sensitivities, no?

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harma
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Post by harma »

I have double DQ genes (I thouhgt 3 but not 100% sure) and yes I have multilple food intolerances, the full "dr Fine" package was all positive Also I fit perfectly in the category "gut takes a long time to heal" and 'takes a long time to full remission". But knowing that it took you Polly and double DQ geners also a long time to finally get there, helps me going. In this way we all can be a example and inspiration for each other. :lol: :lol:
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tex
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Post by tex »

Harma,

You are correct. You do have double DQ3 genes, and one of them is the celiac gene, DQ8.

Tex
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hoosier1
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Post by hoosier1 »

OK. It's been a while since I looked at my numbers. So do I have any significant "doubles"?

*********

A) Gluten Sensitivity Stool and Gene Panel Complete *Best test/best value
Fecal Anti-gliadin IgA 10 Units (Normal Range is less than 10 Units)

Fecal Anti-tissue Transglutaminase IgA 6 Units (Normal Range is less than 10 Units)

Quantitative Microscopic Fecal Fat Score Less than 300 Units (Normal Range is less than 300 Units)

Fecal Anti-casein (cow’s milk) IgA 9 Units (Normal Range is less than 10 Units)

HLA-DQB1 Molecular analysis, Allele 1 0301

HLA-DQB1 Molecular analysis, Allele 2 0602

Serologic equivalent: HLA-DQ 3,1 (Subtype 7,6)

******

Rich
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tex
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Post by tex »

Nope, you're heterozygous, (DQ3,1), with no celiac genes.

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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hoosier1
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Post by hoosier1 »

Bring on the gluten!!!! :) (kidding of course)
"It's not what I believe. It's what I can prove." - A Few Good Men
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tex
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Post by tex »

:lol: Unfortunately, you appear to have 2 non-celiac genes that predispose to gluten sensitivity. :sad:

Tex
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It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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