Polly, And All - What About The Risk Of Vitamin D3 Overdose?

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tex
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Polly, And All - What About The Risk Of Vitamin D3 Overdose?

Post by tex »

I spent most of the morning in the ER. When I got up this morning, I noticed that the fingers of my right hand were sort of "tingly", and kind of numb. I just figured they were "asleep", so I didn't pay much attention, until it started spreading up my arm, and the same thing started happening to the right side of my face. At that point I took an aspirin, and finished dressing, and got a few things together, in case I had to stay overnight in the hospital. Half an hour later, the "symptoms" were a bit worse, (my arm was weaker), so I took another aspirin, and hit the road. Half an hour later, I was sittin' in the ER, thankful that I wasn't in really bad shape, because the place seemed almost deserted, (compared with the usual congestion), and it appeared that no one was in any particular hurry to check me out. LOL.

Anyway, long story short - EKG, chest X-Rays, and blood tests, all seemed normal, as did my vital signs, (except for my blood pressure, of course), and no paralysis was evident, so they sent me home, and told me to call my GP on Monday. The symptoms are still going on, though they are not as bad as they were at the peak. The doc officially called it a TIA, since it improved on it's own, and he prescribed no treatment. Outside of feeling a little dizzy, and generally cruddy, I reckon I'm OK, for the moment.

The ER doc was surprised that my symptoms were somewhat consistent with a stroke, but there was no evidence of muscle weakness, (or paralysis), 2 hours after the onset of symptoms. His opinion that it was a TIA, was a default diagnosis, but I could tell that he wasn't happy with it. (IOW, there's always a chance that it might have been, so naturally we have to err on the side of caution, but I sensed that he felt that something else was going on. I've been home a few hours now, and had a chance to think about this a bit.

I've noticed that during the past week or two, I have experienced somewhat frequent periods of not really dizziness, so much as a feeling of light-headedness (and balance issues, at times). (Does that ring a bell)? Also, my blood pressure seems to be increasing. The diastolic level used to be around 115 to 120, but lately it's been consistently over 120, and often 140 or more, (at the doctor's office). This morning, in the ER, the alarm on the BP monitoring equipment was enough to drive someone crazy, because it went off, every time the dang thing measured my pressure. I assume that it was set at 160, because my pressure was pretty consistent around 165. After a couple of hours, it finally settled down to 157, so the dang alarm quit going off. One other thing that was especially noticeable this morning - as soon as I headed for the ER, my mouth, (and later my throat), became really dry. I was wishing that I had brought some water along, and I couldn't figure out why I was so thirsty. My kidneys seemed to be hyperactive while I was in the ER. Not only was the frequency way up, but so was the volume. I probably wouldn't have noticed the volume, except that they gave me a urinal, (bottle), to use, and I filled it up in about an hour and a half, (more or less), which really surprised me, since I hadn't had anything to drink since I had gone to bed the night before, and I had emptied my bladder before I left to go to the ER.

Okay - consider that I live in Central Texas, where sunshine is almost always plentiful, and it's especially prevalent this year, since we're having a bad drought. We've had an unusually high accumulation of "growing degree days" this year, due to the reduction in the number and density of clouds. Soooooo, I'm probably getting more than enough vitamin D, from sun exposure alone. I've been taking 4,000 IU of vitamin D3, daily, for about 6 or 7 months, now, I believe. I have a number of the symptoms that the Mayo Clinic lists for vitamin D overdose, (including itching skin):
Late symptoms of severe overdose (emerge after months or years of starting supplements)

High blood pressure
High fever
Irregular heartbeat
Stomach pain (severe)

Check with your doctor as soon as possible if any of the following side effects occur:

Early symptoms of overdose (emerge within days or weeks of starting vitamin D supplements)


Bone pain
Constipation (especially in children or adolescents)
Diarrhea
Drowsiness
Dryness of mouth
Headache (continuing)
Increased thirst
Increase in frequency of urination, especially at night, or in amount of urine
Irregular heartbeat
Itching skin
Loss of appetite
Metallic taste
Muscle pain
Nausea or vomiting (especially in children or adolescents)
Unusual tiredness or weakness

Late symptoms of overdose (emerge within weeks or months of starting supplements)

Bone pain
Calcium deposits (hard lumps) in tissues outside of the bone
Cloudy urine
Drowsiness
Increased sensitivity of eyes to light or irritation of eyes
Itching of skin
Loss of appetite
Loss of sex drive
Mood or mental changes
Muscle pain
Nausea or vomiting
Protein in the urine
Redness or discharge of the eye, eyelid, or lining of the eyelid
Runny nose
Weight loss
I have quite a few of those symptoms, though certainly not all of them. For example, I don't seem to have any pain, (I'm not sure if stomach pain is a "required" symptom for vitamin D overdose). I feel tired, and very weak, in particular.

I found the following information in a blog, and I consider it to be very interesting, (the blog was written in December, 2008, so it's a fairly recent blog.)
The problem with milk fortification is that not only is there a wide range of sensitivity to vitamin D, there is also a wide range of intake. In my opinion, this data suggests that sensitive individuals develop vitamin D side effects from daily use of 1000 to 2000 IU of vitamin D. For example, my son drinks an average of 2 to 3 quarts of milk every day. This means he gets between 800 and 1200 IU of vitamin D from milk and then probably averages over the course of the year another 400 IU/day from sun exposure. The babies in Britain showing up with vitamin D side effect were probably getting plenty of sunshine and drinking plenty of fortified milk. My sense that 1000 to 2000 IU regularly causing side effects was reinforced by a thorough internet search for advice on vitamin D supplement programs from clinicians who help clients put together supplement programs. I found several clinician reports of 2000 IU/day doses leading to problems after months of use.

If you’ve been reading my column, and reading the information at the Vitamin D Council website, you’ll know that 1000 to 2000 IU/day is often not enough. So, the hard facts are that there is no known dose of vitamin D that provides everyone with full benefits without causing anyone side effects.
This information is from:

http://www.cforyourself.com/Blog/2008/1 ... fects.html

The symptoms are still present, which makes it a little inconvenient to do some things. For example, eating is like trying to chew food, when half your mouth is still about half-deadened, from a shot of novacaine. Nothing tastes very good, either, so I guess my tongue is partially numb. (Move over Barbara, 'cause I seem to have joined your club). I wasn't able to eat much for lunch, but that's probably a good thing, because I need to lose some weight, anyway. LOL. It's a little tricky typing with partially-numb fingers, too. I'm just glad they're still working as well as they are.

Does anyone have any thoughts on any of this?

Love,
Tex

P. S. Yes, I've stopped taking vitamin D supplements, until I can get a handle on what's going on.

P. P. S. I notice that the list of possible symptoms provided by the Mayo Clinic does not include numbness, nor certain other peripheral neurological effects, so here are some additional symptoms:

Certain nerve symptoms that could be included are particular sensations, pain, reflex issues, numbness, temperature sensitivity, taste symptoms, paresthesias (sensations such as tingling, burning, pins-and-needles, and prickling), hearing impairment, and some others.

From this site:

http://www.helium.com/items/1379631-vitamin-d-overdose
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by barbaranoela »

Galahad!!!!!!! and U be sure to get your GP tomorrow-----cus I shall be keeping my *eye* on U!! :smile:

Lou wants me to tell U---!!Wayne, U dont want Barbara on your case!!! :lol:

Luve and take care--and a good thought about stopping that amount of *D*

:bigbighug:
Mrs. Columbo~~~~~~

PSS. U know we are all react differently to the dosage/or even the meds/ vitamins/in itself~~~~ :drinkingmedicine:
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Post by tex »

Mrs. Columbo,

I definitely will call his office in the morning.
Lou wrote:!!Wayne, U dont want Barbara on your case!!! :lol:
I hear you Lou! And I don't doubt that for a second. Thanks for the heads up. :lol:
PSS. U know we are all react differently to the dosage/or even the meds/ vitamins/in itself~~~~ :drinkingmedicine:
Barbara, I think you have hit the nail right on the head, because that especially applies to vitamin D. We're all going to have to figure out what's best for ourselves, individually, based on where we live, and how we live.

Thanks a million for the phone call - you made my day. It's always a super experience, talking with you.

Much luve,
Galahad
:cowboy:

It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
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Post by JLH »

Hope you are feelin' better, Tex. Hope and pray it's nothing serious and will go away very soon. Let us know what the doc says, please.
DISCLAIMER: I am not a doctor and don't play one on TV.

LDN July 18, 2014

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Post by Lucy »

Hi Wayne,

Do you happen to have any diabetes in your family?
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Post by crranch »

What happened to you sounds very similar to what put Rick in the hospital up here a year ago...He was at work and his left arm didn't want to work correctly, then his legs and he was having trouble finding words, kind of like massive brain fog, but worse.

He did the same thing you did, went to the ER, they ended up keep him overnight, ran a bunch of test and found nothing. Sent him home the next afternoon with a diagnosis of a possible TIA...and told him to go see another Neurologist...Nothing like a night in the hospital and a bill for thousands of dollars and no real diagnosis to make you see red. :twisted:

This was before Rick was taking any vitamin D3, so I know that would not have been a factor for him...but we never did figure out what his was....

Take Care and take it easy, Rick's episode jerked a knot in his tail for days afterwards. Don't push yourself...

Hugs,
C
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Post by starfire »

Just read this and I join in the others... Go see your GP at least and I wish I knew who else to tell you to see. :shock:

Please, Please, Please take care............

Love, Shirley
When the eagles are silent, the parrots begin to jabber"
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Post by ant »

Dear Tex,

Just woken up here in Hong Kong to read your post. .... wishing you all the very, very best and hope you feel better soon.

Ant


PS. I doubt I can add anything useful accept to say when I get bad balance spells they have usually coincided with feeling very thirsty, passing a lot of urine and feeling tired.
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Post by mbeezie »

Hi Tex,

So sorry to hear you are having problems - hopefully your GP will figure it out quickly.

What tests did they run? Electrolytes and calcium came back normal? Did they check PTH?

Hypervitaminosis can certainly be a cause, but it doesn't seem like you were taking that high of a dose - sunshine can only account for bringing you to equilibrium, not excess. With high BP, excess urine output and numbness one of my thoughts was possibly an aldosterone problem - have you had hypertension in the past?

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Post by tex »

Joan,

Thanks - will do.


Luce,

No, no diabetes in the family, that I'm aware of.


Carrie,

That's why I'm glad they sent me home after a few hours. If they're not gonna find anything, why waste the money? The only thing that concerns me is the fact that my symptoms are all on my right side, but for all I know, that could be typical of neurological issues caused by excessive vitamin D buildup.

Yep, I'm still weak, and feeling cruddy, and my blood pressure is still 152/93, but at least my pulse is down to 73, now, (at 10 pm), it was still running in the 80 to 90 range, at mid-day. Anyway, I doubt I'll be doing much besides checking with the doc, tomorrow, (assuming he might be able to squeeze me into his schedule).


Shirley,

Thanks, I appreciate your concern, but as the tests showed, my heart, lungs, blood chemistry, etc., all seem to be sound, and my carotid arteries "sound good", according to the doc at the ER.


Ant,

Thanks. That's interesting about your symptoms. My dry mouth and kidney hyperactivity seemed to be gone, by the time I got back home, interestingly, enough.


Mary Beth,

I honestly don't know which items they checked for, but I would assume that they did a thorough job. I remember that after I mentioned that I take a thyroid supplement, (Armour), he said that they would check to make sure that everything was in order with my thyroid function, so I would assume that they would check out PTH, since that would seem to be important, in a situation such as that, (I'm thinking he mentioned parathyroid hormone, but I honestly don't remember for sure).

I thought it interesting that he had never heard of Armour - when I told him that it's made from dessicated pig hormone, he said, "Oh! You mean something like viagra?" I laughed, and shook my head, (to mean "no"), so he look it up on a PDA that he carries in a pocket. Anyway, he said all the blood work looked normal, the EKG was normal, nothing showed up in the lung X-rays.

Surely they would have mentioned low potassium, if that were the case. I eat 2 or 3 bananas virtually every day, because back before I healed, I was always low on potassium, every time they checked. I think the aldosterone situation is something that my doc and I will want to check out, though, just to be sure.

The blog that I quoted from above, mentions references to individuals who had problems after supplementing with as little as 2,000 IU of vitamin D for several months, (and that apparently included "natural" dietary sources, such as as "enriched" milk, and other "enriched" foods). If I were to include things like that, my dose is even higher. The point is, I don't believe that it's possible to overdose on vitamin D, by the natural process of the skin making it from sunlight, but apparently it is very possible to overdose, with supplements, especially if one is already getting plenty of vitamin D from sunlight.

As I think I mentioned in a previous post, my blood pressure, 6 months to a year ago, was usually in the 115 to 120 over 70 something range, but after I had been taking the vitamin D for a few months, it has typically been in the 130 to 140 over 80 range, (and sometimes slightly higher, especially when taken in the doc's office). I checked it a few minutes ago, and it's still 152/93, (it was 155/91, a few hours ago). I have no proof that the vitamin D supplementation caused the BP problem, but I haven't really changed anything else in my diet.

Thanks everyone,
Tex
:cowboy:

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Post by MaggieRedwings »

Morning Tex,

So sorry to hear of what you are going through and I am sure you will be at the GP's office stat. Do hope you are feeling a bit better. Can't add to what anyone else has said but do know that I am only taking 1000 mg of D3 per day since my GP felt that it was best that way.

Love, Maggie
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Post by kscolorado »

Sorry to hear of your problems Tex. Do you think you could have got some hidden gluten? During my challenge, the right side of my face started going numb and the fingers on my right hand. My sister of course thought I was going into a stroke, but this a gluten symptom for me. Hope you get to the bottom of it...{{{Hugs}}}
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Post by Rosie »

Tex, sorry to hear of your problems. Have you have your blood level of vitamin D checked? That seems like a good place to start. I had my levels checked just a few months ago, as my GP has been regularly checking for low vitamin D levels amongst her pateints with osteopenia. She said that there is a growing awareness amongst doctors that many people are low in vitamin D. My level was low normal, and she wanted me to take 1500 units a day and get a bit more sunshine.


Hopefully you will continue to improve and discover the cause.
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Post by tex »

Morning Maggie,

I am feeling a little better this morning, but very tired, and weak, and my BP is still 149/85 this morning, but at least my heart rate is down to 71. My BP seems to be coming down excruciatingly slowly, but at least it's slowly coming down. I have an appointment for 2:15, so hopefully we'll be able to start making some headway on figuring this out.


Kathy,

Thanks for mentioning those symptoms. I don't recall ever hearing someone describe that kind of gluten reaction before, but I have to admit that the thought did cross my mind, because of the fact that gluten can cross the blood/brain barrier, (which could explain the one-sided effects). l can't see how I could have eaten any gluten the day before, though, and obviously, I've never reacted this way before, either, (of course, there's always a first time for everything).


Rosie,

No I haven't, but 25(OH)D is at the top of my list of things that I'm going to ask my doc to check. I'm curious about B-12, too, since it's notorious for causing issues with numbness/tingling, etc. I haven't taken any supplemental B-12 in a long time, (other than a little in a multivitamin), because I assumed that my malabsorption problem has been corrected by now, but I could be wrong about that. When I was recovering, I used sublingual B-12 regularly.

I've got a long list of things I would like to see checked, (not negotiable, as far as I'm concerned :lol: ), and he can add whatever he wants, to the list.

Thanks everyone.

Tex

P. S. Heck, it was great just to wake up this morning, and realize that I wasn't any worse. :grin:
:cowboy:

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Post by Gayle »

That was a scary and unnerving event Tex :shock: , but since you went to the ER so well prepared, it doesn't sound like you panicked. :smile:

Don't let the Docs forget to consider MIGRAIN. A Neuro consult might be in order if this happens again. I think I recall you having some occasional "migrain auras" recently? When all else fails, go back and look at history.


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