MRT 5000

[Polly]

Mary Beth mentioned this new, upcoming test in another post.

I am wondering who would be considered a candidate for it? Would it benefit some of us who are still having problems teasing out all of our sensitivities? How many things will be tested? (I can't imagine it will be 5000 different things LOL).

MB, I'd love to hear more about this test.

Polly xoxo

[mbeezie]

Polly,

I don't know much about the test - I am sure things are being kept quiet on purpse. From what I know though, it will be the only test to pick up basophil response, which will be helpful for those of us with histamine problems. Basophils, like mast cells, release histamine. Since basophils are in blood and mast cells are not, we will get a much better idea of foods that trigger histamine release.

I doubt there will be more foods tested, but some foods may change.

I am waiting for the new test to come out and will re-test, mostly out of curiosity. I know my profile has changed from my original one in 2009.

As soon as it becomes available I will post something.

Mary Beth

[tex]

Of course, that isn't all that basophils respond to, (food sensitivities). In addition, (according to Wikipedia),

Like eosinophils, basophils play a role in both parasitic infections and allergies[1]. They are found in tissues where allergic reactions are occurring and probably contribute to the severity of these reactions. Basophils have protein receptors on their cell surface that bind IgE, an immunoglobulin involved in macroparasite defense and allergy. It is the bound IgE antibody that confers a selective response of these cells to environmental substances, for example, pollen proteins or helminth antigens. Recent studies in mice suggest that basophils may also regulate the behavior of T cells and mediate the magnitude of the secondary immune response.

The red emphasis is mine, of course. So, IMO, (FWIW), while incorporating basophil response may "complicate" the issue somewhat, by also incorporating possible effects of parasitic infections, and ordinary allergies, their inclusion in the test results may indeed be useful, in view of their connection with the behavior of T cells, (since as we all know, MC is the result of a T cell-connected reaction).

Tex

[Polly]

Thanks for the info!

MB, what is the reason for your profile changing? Do you mean new sensitivities developing or old ones no longer present because of healing? Oh, don't forget to see if they will test for xanthan and guar gums. That was such a great idea.

Love,

Polly

[mbeezie]

I think profile could change if you avoid a food for a while. For example, I was red reactive to lettuce and avoided it for 18 months and recently tried some without incident. I think the potential reaction remains once it is red reactive, but if it is rotated in reasonable amounts it might not be a problem. Some food issues, like gluten, are permanent as we know, but some of these other sensitivities may not be. It may be gut healing or it may be simply the immune system calming down - not sure.

Mary Beth

[Gloria]

I was red reactive to lettuce and avoided it for 18 months and recently tried some without incident.

That's encouraging news, Mary Beth!

Gloria