Why H2 Histamine Blockers (Antacids) Reduce Mast Cell Issues

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Gloria
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Why H2 Histamine Blockers (Antacids) Reduce Mast Cell Issues

Post by Gloria »

I've never understood why an antacid would help a histamine problem. I found this explanation on Medicinenet.com:
BRAND NAME: Zantac
DRUG CLASS AND MECHANISM: Ranitidine is an oral drug that blocks the production of acid by acid-producing cells in the stomach. It belongs to a class of drugs called H2 (histamine-2) blockers that also includes cimetidine (Tagamet), nizatidine (Axid), and famotidine (Pepcid). Histamine is a naturally-occurring chemical that stimulates cells in the stomach (parietal cells) to produce acid. H2-blockers inhibit the action of histamine on the cells, thus reducing the production of acid by the stomach. Since excessive stomach acid can damage the esophagus, stomach, and duodenum and lead to inflammation and ulceration, reducing stomach acid prevents and heals acid-induced inflammation and ulcers. The FDA approved ranitidine in October 1984.
Red highlighting is mine.

Gloria
You never know what you can do until you have to do it.
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