More thyroid stuff

[Deb]

I've been researching possible thyroid issues and stumbled upon this article. http://www.wjgnet.com/1007-9327/15/3122.pdf It may be old news for some of you (it is from 2009). Anyways, they showed an incidence of over 20% of thyroid disease among people with MC. One statement struck me as odd. "MC may evolve into IBD".

My "sensitive TSH" was 4.4 which, according to Mayo isn't an issue but I seem to have quite a few symptoms (except I'm not feeling cold anymore, though I did for years.) I've seen ranges over 3.0 could be an issue. My temp today in the middle of the afternoon was 97.9 so I'm going to watch that. Any thoughts?

[MBombardier]

That's a really good article, Deb, that I had not seen before. I have CC, so this was appropos for me:

Of the CC population identified, the most common endocrinopathies were as follows: hyperlipidemia (42.7%), diabetes (14%) and thyroid disease, including hyperthyroidism, hypothyroidism and Grave’s disease (21%). The three most common rheumatologic and other inflammatory disorders were rheumatoid arthritis (7%), fibromyalgia (3.5%) and Raynaud/CREST syndrome (2.9%). Other diseases diagnosed in these patients included giant cell/temporal arteritis (n = 3, 1.75%), polymyalgia rheumatica (n = 2, 1.16%), systemic
lupus erythematosus (n = 1, 0.58%) and scleroderma (n = 1, 0.58%). Only five patients in the CC group were diagnosed with celiac disease (2.92%). One of these patients had the diagnosis of celiac disease prior to the diagnosis of CC. Thirty patients were diagnosed with irritable bowel syndrome (IBS) prior to the diagnosis of CC, while only one patient was diagnosed with irritable bowel after the diagnosis of CC was made. We observed one patient with an established diagnosis of IBD prior to the diagnosis of CC. During a median follow up of 3 years, none of our CC patients have subsequently been diagnosed with IBD. Compared with the control group, patients with CC had higher rates of thyroid disease (P < 0.001). We also observed a higher rate of celiac disease (P < 0.01), IBS, (P < 0.001) rheumatoid arthritis (P < 0.001) and Rayanud/CREST syndrome (P < 0.01) in our patients with
CC.

Of course, they also talk about LC, and the results are similar.

Here's another one:

Indeed, we found a statistically higher occurrence of thyroid dysfunction in LC and CC patients when compared to the control group. The association between thyroid dysfunction, LC and CC is still unknown, although some suggest autoimmunity as a possible cause.

Ya think?

I went to a new PCP yesterday who had thyroid cancer and does not have a thyroid anymore. Nothing like having a doctor who has the same disease you do. She said that high cholesterol is strongly associated with thyroid disease, so it is interesting to me that this study shows a connection between CC and hyperlipidemia. Not that I agree that high cholesterol is a bad thing, of course.

Thanks for posting this!

[carolm]

Wow Deb, you don't know how timely this is. I see my PCP tomorrow and I'm taking this with me.

thanks
Carol